Chromatograph device

Abstract

Provided is a chromatograph device capable of correct measurement even if the retention times of target components change. This chromatograph device is provided with: a storage unit 41 for storing measurement parameters for a plurality of target components, measurement conditions including measurement parameter switching times for each of two target components eluted in succession, and formulas for determining the switching times from predetermined retention times for the target components; a measurement data accumulation unit 42; a preceding-measurement-data determination unit 43 for determining, at the time of sample measurement, whether there is preceding measurement data for the same column 13 type, mobile phase type, and flow velocity; and a measurement execution unit 44 for carryingout measurement on the basis of the measurement conditions if there is no preceding measurement data and, if there is preceding measurement data, determining the retention times of the target components on the basis of the most recent preceding measurement data, determining updated switching times on the basis of the retention times and formulas, and carrying out measurement with the switching times changed to the updated switching times.

Description

technical field [0001] The present invention relates to a chromatograph device for separating and measuring a plurality of components contained in a sample according to time. In particular, it relates to a chromatograph device which can preferably be used for quantification of known components contained in a sample. Background technique [0002] In a chromatograph device such as a liquid chromatograph or a gas chromatograph, various components contained in a sample are separated over time in a column and sequentially detected by a detector such as a mass analyzer or an absorbance detector. A chromatograph device that uses a mass analyzer as a detector is called a chromatograph mass analyzer. In a chromatograph mass spectrometer, components separated in a column and eluted together with a mobile phase are sequentially ionized, separated by mass, and only ions originating from components in a sample are detected. [0003] In the mass separation described above, there are gen...

AI Technical Summary

Problems solved by technology

As mentioned above, since the timing of switching the holding parameters is determined in advance based on the holding time obtained from the measurement of the standard sample, if the holding time of the target component changes, there is a problem that the next target will be changed before the measurement parameters are switched. Components are eluted from the column, conversely after switching to the measurement parameters of the next eluted target component, the previous target component is eluted from the column, so that the target component cannot be measured correctly

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