Hepatitis B HBsAg, HBeAb, and HBcAb test positive low replication phase pregnant and childbirth period reactivation monitoring equipment

Abstract

The invention discloses a hepatitis B HBsAg, HBeAb, and HBcAb test positive low replication phase pregnant and childbirth period reactivation monitoring equipment, and belongs to the technical field of medical equipment. The hepatitis B HBsAg, HBeAb, and HBcAb test positive low replication phase pregnant and childbirth period reactivation monitoring equipment is a flexible, safe, standard HBV infection reactivation monitoring equipment, is capable of reducing adverse pregnancy caused because of delayed discovery of reactivation states. The hepatitis B HBsAg, HBeAb, and HBcAb test positive lowreplication phase pregnant and childbirth period reactivation monitoring equipment comprises a prediction index detection device used for detecting hepatitis B HBsAg, HBeAb, and HBcAb test positive low replication phase pregnant and childbirth period reactivation prediction index series, and a data analysis device used for obtaining a nomograph taking prediction index detection data as variables based on the detection data obtained using the prediction index detection device. The hepatitis B HBsAg, HBeAb, and HBcAb test positive low replication phase pregnant and childbirth period reactivationmonitoring equipment is used for monitoring hepatitis B HBsAg, HBeAb, and HBcAb test positive low replication phase pregnant and lying-in woman reactivation states.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to a monitoring device for reactivation during pregnancy and childbirth during low replication of hepatitis B small three yang. Background technique [0002] The chronic HBV (hepatitis B virus, hepatitis B virus) infection process generally includes: immune tolerance period, immune clearance period and low replication period. Patients with chronic HBV in the low-replication stage are what we commonly call "small three yang patients". Patients in the low replication phase account for 70-80%. It is characterized by HBeAg (hepatitis B E antigen) disappearance, anti-HBe (hepatitis B e antibody) appears, ALT (alanine aminotransferase, alanine aminotransferase) remains normal, and HBV DNA (hepatitis B virus deoxyribonucleic acid, Hepatitis B virus DNA) remains low It can't even be detected at 2000copies / mL (PCR method). Therefore, it is generally considered that patients in t...

AI Technical Summary

Problems solved by technology

However, for pregnant women with chronic HBV infection, this kind of immune tolerance and immunosuppression is likely to lead to increased maternal reactivation during the low replication phase of chronic HBV infection

The large increase of estrogen and progesterone during pregnancy increases the burden on the mother’s liver, which may also be the triggering factor for the increase of reactivation during pregnancy, but there is no relevant clinical prospective study

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