Traditional Chinese medicine for treating sjogren syndrome

A technology for Sjögren's syndrome and traditional Chinese medicine, which is applied in the direction of drug combination, medical formula, medical preparations containing active ingredients, etc. It can solve the problem of destroying the compatibility of traditional Chinese medicine prescriptions, increasing efficiency and reducing toxicity, unsatisfactory treatment effects, and a wide variety of Chinese medicines, etc. problem, to achieve the effect of enhancing autoimmune function, low treatment cost and remarkable curative effect

Inactive Publication Date: 2018-11-20
ZHANGJIAGANG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although there are many drugs prepared by extracting individual components of traditional Chinese medicine on the market, the preparation process destroys the synergistic and attenuating effect of the compatibility of traditional Chinese medicine prescriptions. These drugs generally have disadvantages such a

Method used

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Examples

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Comparison scheme
Effect test

specific Embodiment 1

[0010] Weigh 20g of Ophiopogon japonicus, 15g of raw land, 10g of Adenophora, and 20g of Artemisia annua, and decoct in water twice a day orally;

[0011] The advantages of the present invention are: among the components of the traditional Chinese medicine, Shengdi clears heat and cools blood, nourishes yin and promotes body fluid; Radix Ophiopogon japonicus and Adenophora nourishes yin and moistens lungs, nourishes stomach and promotes body fluid; Artemisia annua can regulate specific transcription in Th1 / Th2 cell differentiation process The mRNA expression levels of factors T-bet and GATA-3 can increase the level of TGF-β1 and inhibit the expression of phosphorylation activity of p38 MAPK, so as to achieve the curative effect of inhibiting local inflammatory reactions, and have the functions of clearing deficiency heat, cooling blood and eliminating steam Playing the functions of clearing heat and cooling blood, nourishing yin, promoting body fluid and moistening dryness, it ...

specific Embodiment 2

[0022] Weigh 10g of Ophiopogon japonicus, 12g of raw land, 6g of sand ginseng, and 15g of Artemisia annua. Make tea and drink instead of water. During drinking, avoid wind and cold, soothe your emotions, avoid fat, sweet, greasy, and spicy food.

[0023] The advantages of the present invention are: the advantages of the present invention are: in the components of the traditional Chinese medicine, Shengdi clears heat and cools blood, nourishes yin and promotes body fluid; Ophiopogon japonicus and Adenophora nourishes yin and moistens lungs, nourishes stomach and promotes body fluid; Artemisia annua can regulate Th1 / Th2 cells During the differentiation process, the mRNA expression levels of specific transcription factors T-bet and GATA-3 can increase the level of TGF-β1 and inhibit the expression of phosphorylation activity of p38 MAPK, so as to achieve the curative effect of inhibiting the local inflammatory response, and has the effect of clearing deficiency heat, Cooling the b...

specific Embodiment 3

[0034] Weigh 18g of Ophiopogon japonicus, 18g of raw land, 9g of Adenophora, and 25g of Artemisia annua, decoct in water and take orally twice a day. During the period of taking the medicine, take shelter from the wind and cold, soothe the emotions, avoid fat, sweet, thick and greasy food, and avoid spicy and stimulating food.

[0035] The advantages of the present invention are: among the components of the traditional Chinese medicine, Shengdi clears heat and cools blood, nourishes yin and promotes body fluid; Radix Ophiopogon japonicus and Adenophora nourishes yin and moistens lungs, nourishes stomach and promotes body fluid; Artemisia annua can regulate specific transcription in Th1 / Th2 cell differentiation process The mRNA expression levels of factors T-bet and GATA-3 can increase the level of TGF-β1 and inhibit the expression of phosphorylation activity of p38 MAPK, so as to achieve the curative effect of inhibiting local inflammatory reactions, and have the functions of c...

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Abstract

The invention discloses a traditional Chinese medicine for treating a sjogren syndrome. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 8-30parts of radix ophiopogonis, 8-30 parts of radix rehmanniae, 5-15 parts of radix adenophorae and 5-35 parts of sweet wormwood herb. The traditional Chinese medicine has the advantages as follows: among the components of the traditional Chinese medicine, the radix rehmanniae has the effects of clearing away heat, cooling blood, nourishing Yin and promoting secretion of the body fluid; the radix ophiopogonis and the radix adenophorae have the effects of nourishing Yin, clearing away the lung heat, tonifying stomach and promoting secretion of the body fluid; the sweet wormwood herb has the effects of clearing away the deficiency heat, cooling blood and clearing hectic heat; the components jointly achieve the effects of clearing away heat, cooling blood, nourishing Yin, promoting secretion ofthe body fluid and moistening dryness, so that the traditional Chinese medicine can effectively enhance and adjust the autoimmune function; the traditional Chinese medicine is strict in compatibility, integrates Chinese and western medicines, treats both symptoms and root causes, prevents relapse and aggravation, has the effects of clearing away heat, cooling blood, nourishing Yin and promoting secretion of the body fluid, is high in using safety, significant in therapeutic effect, low in side effects, low in treatment cost and high in patient compliance, can be drunk as tea for a long term time, or can be orally taken by decocting, or can be carried about in form of granules.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine formulas, in particular to a traditional Chinese medicine for treating Sjogren's syndrome. Background technique [0002] Sjögren's syndrome (SS) is a chronic autoimmune disease mainly invading exocrine glands such as lacrimal glands and salivary glands. The pathogenesis includes the expression of anti-SS-A and anti-SS-B autoantibodies, the activation of B lymphocytes, Cytokines such as IL-1, IL-2, IL-6, IL-10, TNF-α, and TNF-β act to damage glandular function, inhibit Th-2 cells in the body, and cannot reach target organs to inhibit local inflammation reaction. The main manifestations of patients are obvious dry mouth, dry eyes, no tears, foreign body sensation, difficulty in entering dry food, etc. There are also systemic manifestations of lung, kidney and other multiple organ involvement. The onset of this disease is slow, and the course of the disease is long. At present, there is ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P37/02
CPCA61K36/23A61K36/282A61K36/34A61K36/342A61K36/804A61K36/8968A61P37/02A61K2300/00
Inventor 朱科达顾惠英陈双双刘风云吴怡
Owner ZHANGJIAGANG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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