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Chemical sensor

A technology of chemical sensors and oxides, which is applied in the field of chemical sensors, can solve problems such as the inability to obtain high detection accuracy, and achieve the effect of high detection accuracy

Active Publication Date: 2018-11-23
TDK CORPARATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

More specifically, there is a problem that the resistance value (or the change amount of the resistance value) of a magnetoresistance effect element when one magnetic bead is arranged on the magnetoresistance effect element is different from that between adjacent magnetoresistance effect elements. The resistance value (or the change amount of the resistance value) of the magnetoresistance effect element is different when it is on the area of ​​the magnetoresistance effect element (on the surrounding area of ​​the magnetoresistance effect element). As a result, when the magnetic beads are arranged on the magnetoresistance effect element and adjacent In both areas between the magnetoresistance effect elements (in the area around the magnetoresistance effect element), even if the number of magnetic beads accumulated on the protective film is the same, the resistance value of the magnetoresistance effect element will vary depending on the magnetic field. High detection accuracy cannot be obtained due to changes in bead configuration

Method used

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Embodiment Construction

[0054] Preferred modes for carrying out the present invention will be described in detail with reference to the drawings. The present invention is not limited by the contents described in the following embodiments. In addition, the constituent elements described below include elements within the substantially same and equal ranges that can be easily conceived by those skilled in the art. Furthermore, the constituent elements described below can be combined as appropriate. In addition, various omissions, substitutions, or changes of constituent elements can be made without departing from the gist of the present invention.

[0055]

[0056] figure 1 is a perspective view of the main part of the chemical sensor 100 of the first embodiment, figure 2 is along figure 1 The sectional view of line II-II. The chemical sensor 100 detects a substance to be detected 40 in a sample. The chemical sensor 100 has a substrate 1 , a magnetoresistance effect element 3 arranged on the su...

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Abstract

The invention discloses a chemical sensor that can achieve high detection precision. A chemical sensor (100) that is characterized by having a substrate (1), a magnetoresistance effect element (3) that is arranged above the substrate (1), a first film (10) that is arranged above the magnetoresistance effect element (3), and a second film (20) that is arranged in a region that surrounds the magnetoresistance effect element (3) or above the region that surrounds the magnetoresistance effect element (3), the solubility of the second film (20) with respect to a specific liquid being greater than that of the first film (10).

Description

technical field [0001] The present invention relates to a chemical sensor for detecting a substance to be detected in a sample. Background technique [0002] In recent years, for the purpose of identifying, preventing, and diagnosing diseases, the development of devices (sensors) that detect the concentration or presence of biomarkers such as proteins, bacteria, viruses, and nucleic acids in a subject is advancing (for example, see Patent Documents 1, 2). [0003] In Patent Document 2, as a sensor for detecting target molecules (biomolecules) in a sample, it is shown that there are a plurality of GMR sensor bars (magnetoresistive effect elements), and the surface of the magnetoresistance effect element is covered with an insulating layer ( protective film) covered sensor. In addition, Patent Document 2 describes a method for detecting target molecules (biomolecules) using such a sensor having a magnetoresistance effect element as follows: Molecule binding receptors (affin...

Claims

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Application Information

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IPC IPC(8): G01N27/72G01N33/543
CPCG01N33/54373G01N33/54393B82Y25/00G01N27/745G01R33/098G01R33/093G01N15/0656B82Y15/00G01N15/01G01N27/72G01N33/543G01R33/1269C12Q1/6825B01L3/502715C12Q2565/629G01N27/00
Inventor 坪池祥生原谷进北川寿美子菊川隆柚贺春希
Owner TDK CORPARATION
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