Pure-plant starch capsule and preparation method thereof

A pure plant and starch technology, applied in the field of biomedicine, can solve problems such as unsatisfactory mechanical strength, and achieve the effect of excellent disintegration time limit and high mechanical strength

Active Publication Date: 2018-11-30
上海国创医药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are still relatively few studies on starch empty sacs. Although there have been some patent reports, the formula still needs to be improved and perfected, mainly because of the unsatisfactory mechanical strength.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A pure plant starch empty capsule comprises the following raw materials by weight: 32 parts of soluble starch, 12 parts of honeysuckle extract, 4 parts of pale bamboo leaves, 5 parts of sucrose, 0.7 part of gelling agent and 0.7 part of plasticizer.

[0026] The soluble starch is prepared from sweet potato starch; the gelling agent is carrageenan; and the plasticizer is glycerol.

[0027] The preparation method of honeysuckle extract: placing fresh honeysuckle in a blast drying oven to dry to constant weight, pulverizing, and passing through a 100-mesh sieve to obtain honeysuckle powder; adding ethanol solution to the honeysuckle powder, refluxing for multiple extractions, and combining the extracts; The extract is cooled, filtered, and then concentrated to half of the original volume to obtain the honeysuckle extract.

[0028] The preparation method of the starch empty capsule of pure plant described in the present embodiment, comprises the following steps:

[0029] 1...

Embodiment 2

[0036] A pure plant starch empty capsule, comprising the following raw materials according to parts by weight: 37 parts of soluble starch, 15 parts of honeysuckle extract, 6 parts of pale bamboo leaves, 7 parts of sucrose, 0.9 part of gelling agent, and 0.9 part of plasticizer.

[0037] The soluble starch is prepared from sweet potato starch; the gelling agent is konjac gum; the plasticizer is polyethylene glycol 200.

[0038] The preparation method of honeysuckle extract: placing fresh honeysuckle in a blast drying oven to dry to constant weight, pulverizing, and passing through a 100-mesh sieve to obtain honeysuckle powder; adding ethanol solution to the honeysuckle powder, refluxing for multiple extractions, and combining the extracts; The extract is cooled, filtered, and then concentrated to half of the original volume to obtain the honeysuckle extract.

[0039] The preparation method of the starch empty capsule of pure plant described in the present embodiment, comprises ...

Embodiment 3

[0047] A pure plant starch empty capsule comprises the following raw materials by weight: 40 parts of soluble starch, 18 parts of honeysuckle extract, 8 parts of pale bamboo leaves, 8 parts of sucrose, 1.2 parts of gelling agent and 1.2 parts of plasticizer.

[0048] The soluble starch is prepared from sweet potato starch; the gelling agent is gellan gum; and the plasticizer is polyethylene glycol 400.

[0049] The preparation method of honeysuckle extract: placing fresh honeysuckle in a blast drying oven to dry to constant weight, pulverizing, and passing through a 100-mesh sieve to obtain honeysuckle powder; adding ethanol solution to the honeysuckle powder, refluxing for multiple extractions, and combining the extracts; The extract is cooled, filtered, and then concentrated to half of the original volume to obtain the honeysuckle extract.

[0050] The preparation method of the starch empty capsule of pure plant described in the present embodiment, comprises the following st...

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PUM

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Abstract

The invention discloses a pure-plant starch capsule. The pure-plant starch capsule comprises the following raw materials by weight: 32 to 47 parts of soluble starch, 12-23 parts of honeysuckle flowerextract, 4-12 parts of Herba Lopatheri, 5-11 parts of sucrose, 0.7-1.6 parts of a gelata and 0.7-1.6 parts of a plasticizer. The pure-plant starch capsule of the invention is prepared according to a pure plant recipe and is safe and reliable to use; and the pure-plant starch capsule has high mechanical strength under the synergistic action of the synergistic components consisting of the honeysuckle flower extract and Herba Lopatheri; and a reasonable preparation method is used so as to allow the starch capsule to be excellent in disintegration time.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a pure plant starch empty capsule and a preparation method thereof. Background technique [0002] Drugs in capsules are generally powders or granules that are irritating to the esophagus and gastric mucosa, or drugs that have a bad taste, are easily volatile, are easily decomposed by saliva in the oral cavity, and are easily inhaled into the trachea. These medicines are packed into capsules, which not only protect the medicinal properties of the medicines from being destroyed, but also protect the digestive organs and respiratory tract. Removing the capsule shell may result in drug loss, drug waste, and reduced efficacy. In addition, some drugs need to be dissolved and absorbed in the intestine, and the capsule protects the drug from being destroyed by stomach acid. In medicine, it refers to a capsule made of special film-forming materials (such as gelatin, cellulose, polysaccharide,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/36A61K47/46
CPCA61K9/4816
Inventor 刘会
Owner 上海国创医药股份有限公司
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