45 results about "Callicarpa kwangtungensis" patented technology

The invention discloses a multicomponent simultaneous assay method and a fingerprint spectrum construction method of callicarpa kwangtungensis and applications thereof. The assay method includes the steps of performing ultrafast liquid chromatographic detection and high-separation-degree fast liquid chromatographic detection or ultra-high performance liquid chromatographic method to a sample solution of the callicarpa kwangtungensis. The fingerprint spectrum construction method of the callicarpa kwangtungensis includes the steps of (1) detecting the callicarpa kwangtungensis with the detection method, and (2) generating a fingerprint spectrum of the callicarpa kwangtungensis with similarity evaluation software. The assay method of the callicarpa kwangtungensis is simple in operation, is excellent in stability, precision and repeatability, is good in chromatographic peak separation degree of the callicarpa kwangtungensis and is short in analysis time. The obtained fingerprint spectrum of the callicarpa kwangtungensis can be used for controlling the quality of the callicarpa kwangtungensis comprehensively so that quality controlling of the callicarpa kwangtungensis is more comprehensive and scientific.

The invention discloses a rapid artificial cultivation method for Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine to solve the problem of lack of a rapid artificial cultivation method for Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine. The method is to cut a strong 1 to 2 year old lignified twig of Callicarpa kwangtungensis Chun into a 10 to 15 centimeter cutting, plant the cutting in a sandy soil with organic fertilizer and a pH value of from 4 to 7, spray foliage application during young shoot stages in summer and fall, keep the height of the seedling within 100 centimeters to shorten and strengthen the seedling and transplant the seedling 7 to 8 months after planting. The method is used for rapid artificial cultivation of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine and has advantages of small character variation, large propagation coefficient, high working efficiency, low seedling raising cost, working efficiency increased by 300 percent compared with vegetative propagation and propagation by grafiting and so on, 98 percent survival rate, 30,000 seedlings for each mu, an income of 8,000 for each mu and good market prospect.

The invention discloses a quality inspection method of anti-hysteritis soft capsules. The quality inspection method comprises the following steps: determining the content of linderane and stachydrine hydrochloride in the anti-hysteritis soft capsules by a high performance liquid chromatography, wherein the content of radix lindera in each capsule is not less than 0.23mg according to the weight of linderane; carrying out thin-layer chromatography on leonurus, and authenticating Guangdong callicarpa bodinieri and radix lindera simultaneously. The quality inspection method disclosed by the invention is high in determination efficiency, high in accuracy, accurate in determination content, and capable of effectively detecting and controlling product quality.

The invention discloses a rapid artificial propagation method for seeds of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine to solve the problem of lack of a rapid artificial propagation method for seeds of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine. The method is to store mature fruit of Callicarpa kwangtungensis Chun in an environment at a temperature of 2 to 8 DEG C, remove the fruit peel and pulp before seeding, sowing seeds in nutritious soil on a seedling bed at a temperature of more than 8 DEG C, transplant a seedling in to a sandy soil when the seedling grows 15 to 20 centimeters long and cultivate the seedling for 5 to 8 month humidity maintenance of the soil, waterlogging prevention, fertilization, weeding and insect control, and transplant the seedling during a period from December or February of the following year. The method is used for rapid artificial propagation of seeds of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine and has advantages of practicality and simpleness, large propagation coefficient, rapid seedling emergency, more than 95 percent emergency and survival rate and good market prospect.

The invention discloses a traditional Chinese medicine decoction for treating osteoarthritis and a preparation method thereof. The traditional Chinese medicine decoction is prepared from, by weight, 17-35 parts of radix achyranthis bidentatae, 12-29 parts of astragalus membranaceus, 8-16 parts of abrus herbs, 11-24 parts of snakegourd seeds, 10-18 parts of cistanche deserticola, 5-12 parts of immature fruits of terminalia chebula, 15-28 parts of pacria fe-te-tarrae, 7-16 parts of tinospora sinensis merr, 3-9 parts of kwangtung beautyberry, 5-15 arts of rhizoma gastrodiae, 4-16 parts of corydalis bungeana, 5-21 parts of fructus aurantii immaturus, 9-23 parts of alocasia cucullata, 10-19 parts of rhiaoma iridis tectori and 12-28 parts of bark of eucommia. The traditional Chinese medicine has the effects of tonifying the kidneys and benefiting essence, tonifying both qi and blood, activating blood and removing blood stasis, dredging the channels and strengthening the muscles and bones, dispelling wind evil and removing dampness, and stopping pain and removing paralysis and has a remarkable treatment effect on osteoarthritis caused by various causes. The materials selected for the traditional Chinese medicine decoction are all traditional Chinese medicine materials, medicine sources are easy to obtain, the curative effect is remarkable, and the traditional Chinese medicine decoction has no toxic and side effects.

The invention relates to a preparation method for acquiring effective substance groups with anti-ulcerative-colitis activity by separation from callicarpa kwangtungensis and compound extract thereof and application of the effective substance groups to preparation of medicines for treating immune inflammations. Particularly, the effective substance groups are acquired by adoption of a membrane separation focused separation technology and used for preparation of medicines for treating immune inflammations including ulcerative colitis.

The present invention discloses a method for separating total flavonoid glucuronide and total phenylethanoid glycoside in Callicarpa kwangtungensis Chun. The method is as below: 1) mixing Callicarpa kwangtungensis Chun powder with water or aqueous ethanol, extracting and concentrating to obtain a concentrated liquid; 2) passing the concentrated liquid through a macroporous resin column, wherein the sampling volume is 1 / 5-2 times of the column volume, removing impurities by water of 4-6 times of the column volume, and eluting the macroporous adsorption resin column with 15-25% ethanol aqueous solution in the volume 3-5 times of the column volume to obtain total flavonoid glucuronide; 3) eluting the macroporous resin column with 35-45% ethanol aqueous solution in the volume 3-5 times of the column volume to obtain a total phenylethanoid glycoside crude product; and 4) passing the total phenylethanoid glycoside crude product through a polyamide resin column, wherein the maximum sampling volume is 1g / mL, and eluting with 5-30% ethanol aqueous solution in the volume 3-6 times of the column volume to obtain the total phenylethanoid glycoside. The separation method can effectively separate total flavonoid glucuronide and total phenylethanoid glycoside, and is simple, practical and applicable to industrial production.

The invention discloses a Chinese herbal medicine extract composition for preventing diaper dermatitis and an application method of the composition. The composition consists of the following components in parts by weight: 2-6 parts of comfrey extract, 4-5 parts of aloe extract, 2-5 parts of callicarpa kwangtungensis extract, 3-7 parts of salvia extract and 2-8 parts of coptis chinensis extract. The application method comprises the following steps: uniformly blending and mixing the components, preparing the obtained mixture into a 45-55% solution by using 80-95% ethanol, uniformly spraying the solution on a paper diaper or diaper upper layer by using an ultrasonic atomizer, so that 5-10g of Chinese herbal medicine extract composition is contained in the material per square meter. According to the produced paper diaper or diaper, diaper dermatitis in infants can be prevented, and fungal and bacterial infestations caused by the reason that urine stains and excrements are not timely cleaned are avoided.

The invention discloses callicarpa kwangtungensis polysaccharide as well as an extraction method and an application thereof. The callicarpa kwangtungensis homogeneous polysaccharide extracted and separated from callicarpa kwangtungensis comprises mannose, rhamnose, glucuronic acid, galacturonic acid, glucose, galactose and arabinose in the molar ratio of 1:19.14:1.02:3.28:24.16:4.68:1.62; the relative molecular mass is 42.02 KDa; the polysaccharide content is 85% or higher, and the acidic sugar content is 10% or higher; and glucosidic bond types comprise T-alpha-arabinose, ->4-beta-galactose-(1->,->2,4-alpha-rhamnose-(1->,->4-alpha-galacturonic acid-(1->and->->4,6-alpah-glucose-(1->. The callicarpa kwangtungensis polysaccharide CKP-1 has good application prospects in preparation of procoagulant-related drugs.

The invention relates to an anti-cervicitis preparation prepared by 167 parts of callicarpa kwangtungensis chun dry extracts, 44 parts of motherwort dry extracts, 39 parts of radix linderae dry extracts, 3-14 parts of micro silica gel and 2-10 parts of water by weight. The invention also relates to a preparation method of the anti-cervicitis preparation. The preparation of the invention has novelcomposition and production technology and strong practicability. By selecting appropriate auxiliary materials and adopting new granulation method, the production cycle is shortened, the labor intensity is lowered and the problems of difficult granulation by the original technology, low granule yield, poor granule quality, high cost, potential safety hazards and the like are overcome.

The invention provides an extraction method of parts of total flavonoids of callicarpa kwangtungensis chun. The invention is designed against that the Chinese herbal medicine callicarpa kwangtungensis chun is lack of direct extraction method of the parts of the total flavonoids with the good effects. The extraction method adopts 50 percent to 60 percent of alcohol to carry out the reflux extraction of the callicarpa kwangtungensis chun, so the extraction method is not only simple and easy to be operated, but can also achieve the good extraction effects.

The invention discloses a preparation method of a soft capsule for treating hysteritis, including the following steps: three medicines, namely, 167 parts of callicarpa kwangtungensis dry extract, 44 parts of motherwort dry extract and 39 parts of radix linderae dry extract are ground into fine powder and evenly blended to obtain dry extract powder; the dry extract powder is added with the mixture of polyethylene glycol 400 and polyethylene glycol 4,000 which accounts for 8% of the total weight of finished products, the proportion of the dry extract to the mixture of polyethylene glycol 400 and 8% polyethylene glycol 4,000 is 1:1.5 to 2; the preparation of a capsule shell is as follows: gelatin liquid is prepared according to the proportion that gelatin: water: glycerin is 1:1:0.4, put into a gelatin dissolving tank and the temperature is set to be 70-80 DEG C; when the gelatin liquid is completely melted, the temperature is set to be 55-65 DEG C and is maintained for about 8 hours. Then pelleting, shaping, drying and packaging are carried out. The soft capsule can prevent air oxidation and moisture absorption and has the advantages of short disintegration time, no leakage of medicine, good stability, high utilization rate and good curative effect.

The invention provides a Callicarpa kwangtungensis chun. low-polarity ingredient extract, which is characterized by comprising 15-28% of aliphatic acid compound, 30-45% of hydrocarbon compound and 2-8% of terpene component. The invention also provides a preparation method for a Callicarpa kwangtungensis chun. essential oil extract, a pharmaceutical composition containing the Callicarpa kwangtungensis chun. essential oil extract, and an application.

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating hemorrhoids and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight as follows: 2-6 parts of callicarpa kwangtungensis, 0.5-1.5 parts of combined spicebush roots, 0.5-2 parts of herba leonuri and 0.5-1.5 parts of sophora flower buds. The formula has good therapeutic effects, can relieve pain quickly and can greatly relieve pain of a patient when treating the hemorrhoids. The traditional Chinese medicine components of the formula are convenient to use, take effects quickly, cause no sequelae and have no toxic or side effects. The traditional Chinese medicine composition only comprises four raw materials, is simple to produce, can be applied to focuses directly and has significant effects.

The invention provides a purifying and enriching method of parts of total flavonoids of callicarpa kwangtungensis chun. The invention is designed against that the Chinese herbal medicine callicarpa kwangtungensis chun is lack of the purifying and enriching method of the parts of the total flavonoids with the good effects. The purifying and enriching method of the invention changes the absorption performances of the parts of the total flavonoids of the callicarpa kwangtungensis chun by regulating pH value of extract liquid of the callicarpa kwangtungensis chun and adopts the static absorption mode, and the method can effectively improve the enrichment efficiency of the parts of the total flavonoids of the callicarpa kwangtungensis chun. In addition, the method only uses small amount of water after the absorption on the column of the extract liquid to achieve the effect of removing impurities, thus being the purifying method which saves resources and time.

The invention provides a purifying and enriching method of parts of total flavonoids of callicarpa kwangtungensis chun. The invention is designed against that the Chinese herbal medicine callicarpa kwangtungensis chun is lack of the purifying and enriching method of the parts of the total flavonoids with the good effects. The purifying and enriching method of the invention changes the absorption performances of the parts of the total flavonoids of the callicarpa kwangtungensis chun by regulating pH value of extract liquid of the callicarpa kwangtungensis chun and adopts the static absorption mode, and the method can effectively improve the enrichment efficiency of the parts of the total flavonoids of the callicarpa kwangtungensis chun. In addition, the method only uses small amount of water after the absorption on the column of the extract liquid to achieve the effect of removing impurities, thus being the purifying method which saves resources and time.

The invention belongs to the field of traditional Chinese medicines, and relates to a composition for treating haemorrhoids and an application thereof, and the Chinese herbal medicine composition comprises the following components in parts by weight: 2-6 parts of callicarpa kwangtungensis, 0.5-2 parts of lindera aggregata, 0.5-2 parts of motherwort, 0.5-2 parts of sophora flower, 0.2-0.7 part of borneol and 0.2-0.7 part of musk. When used for treating haemorrhoids, the composition has the effects of promoting blood circulation, stopping bleeding, removing heat, detoxifying, guiding qi downward, relieving pain, warming kidney, dispelling cold, clearing liver-fire, inducing resuscitation, clearing heat, diminishing swelling and relieving pain. The pain of a patient can be greatly relieved, and the traditional Chinese medicine composition is safe, effective and high in cure rate.

The invention discloses application of callicarpa kwangtungensis and an extract thereof in preparation of anti-peptic ulcer medicaments. Peptic ulcer diseases include a gastric ulcer and a duodenal ulcer. When the callicarpa kwangtungensis is applied to preparation of the medicaments for treating peptic ulcer diseases, the contents of forsythiaside B and poliumoside in the callicarpa kwangtungensis extract at least reach up to either 1.2% or 0.6%. The callicarpa kwangtungensis and the extract thereof have the treatment effects on the peptic ulcer caused by various factors, can obviously promote the ulcer healing, and can prepare the anti-peptic ulcer medicaments.

The invention discloses a rapid artificial propagation method for seeds of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine to solve the problem of lack of a rapid artificial propagation method for seeds of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine. The method is to store mature fruit of Callicarpa kwangtungensis Chun in an environment at a temperature of 2 to 8 DEG C, remove the fruit peel and pulp before seeding, sowing seeds in nutritious soil on a seedling bed at a temperature of more than 8 DEG C, transplant aseedling in to a sandy soil when the seedling grows 15 to 20 centimeters long and cultivate the seedling for 5 to 8 month humidity maintenance of the soil, waterlogging prevention, fertilization, weeding and insect control, and transplant the seedling during a period from December or February of the following year. The method is used for rapid artificial propagation of seeds of Callicarpa kwangtungensis Chun which is a plant used in traditional Chinese medicine and has advantages of practicality and simpleness, large propagation coefficient, rapid seedling emergency, more than 95 percent emergency and survival rate and good market prospect.

The invention discloses a traditional Chinese medicine preparation for treating diabetes and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw materials: astragalus, folium turpiniae, gynostemma, callicarpa kwangtungensis, medulla stachyuri, hairy euphorbia, grass, henbane, rhizoma anemarrhenae, fructus schisandrae, avicennia pricklyash root, centipeda minima, anemone hupehensis and liquorice. The traditional Chinese medicine is reasonable in formula, rich in raw material, simple in preparation method, low in price, and convenient to take by patients; the clinical observation for many years indicates that the traditional Chinese medicine can obviously improve symptoms of polydipsia, diuresis, polyphagia, emaciation and fatigue and lack of strength caused by diabetes, and significantly reduce blood glucose.

The invention relates to the technical field of plant extraction and analysis, in particular to an extraction method of callicarpa kwangtungensis polysaccharides, which comprises the following steps: extracting effective components from callicarpa kwangtungensis by a microwave alcohol extraction method, separating macromolecules, continuing high-performance counter-current chromatography separation, and finally obtaining the callicarpa kwangtungensis polysaccharides by a column chromatography elution separation technique. The method comprises the following steps: extracting effective components to obtain an extract, removing colloid unstable components such as tannin, protein, resin, wax paper and the like in the extract, carrying out high performance countercurrent chromatography treatment, and removing water-insoluble organic matters, so that the retained water-soluble substances contain water-soluble polysaccharides, water-soluble amino acids and polypeptides; and finally, effectively separating the callicarpa kwangtungensis polysaccharide by adopting a column chromatography elution separation technology to obtain the callicarpa kwangtungensis polysaccharide with high purity.

The invention discloses a method for preparing high-purity poliumoside. The method comprises the following steps of: smashing callicarpa kwangtungensis serving as a medicinal material; adding a 50-70 percent acetone solution in an amount which is 5-7 times that of the medicinal material for performing ultrasonic extraction for 2-3 times; filtering the extracting solution to recover a solvent; adding a concentrated solution into water-saturated n-butyl alcohol for extracting; making the extraction liquid pass through a short aluminum oxide column; recovering a reagent from the column passing liquid; separating the obtained extract by adopting a high-speed counter-flow chromatography; detecting with an ultraviolet detector; collecting a target component; and drying under reduced pressure to obtain a poliumoside monomer. The method for preparing the high-purity poliumoside has simple process steps, large preparation amount and a short period, and the purity of the obtained product is not less than 98 percent.

The invention relates to a feed additive capable of improving sow productivity and preparation and using methods thereof, which belong to the technical field of feed additives. The feed additive capable of improving sow productivity consists of the following components in parts by weight: 16-25 parts of dry callicarpa Kwangtungensis extract, 4-8 parts of dry leonurus japonicus extract, 2-5 parts of dry rhizoma cyperi extract, and 2-4 parts of dry scutellaria baicalensis extract. The feed additive capable of improving sow productivity is prepared by the following steps: grinding natural plant extracts of callicarpa Kwangtungensis, leonurus japonicas, rhizoma cyperi and scutellaria baicalensis oin a mass ratio into fine powder, and adding proper amount of an auxiliary material to obtain a powder agent. The feed additive is capable of effectively improving sow immunity and sow productivity, and promoting healthy growth of piglets.

The invention discloses a traditional Chinese medicine composition for anti-uterus inflammation and a preparing method thereof. The composition comprises callicarpa kwangtungensis dry extract, leonurus dry extract and combined spicebush root dry extract, which are prepared by steps of cutting up callicarpa kwangtungensis, leonurus and combined spicebush root respectively, decocting the materials twice with water added respectively, concentrating and drying the materials under reduced pressure respectively. The composition is prepared by steps of smashing the dried dry extracts into fine powders respectively, mixing the powders evenly in accordance to a ratio and drying the powders. The traditional Chinese medicine composition for anti-uterus inflammation has high contents of forsythiaside B and poliumoside, and has the functions of clearing heat and expelling damp, and dispersing blood stasis and arresting leucorrhea, and can be used for treating diseases of morbid leucorrhea, leucorrhea with reddish discharge, profuse and smelly leucorrhea and erosion of cervix and the like which are caused by downward flow of damp-heat. With only the traditional Chinese medicine composition for anti-uterus inflammation, the diseases can be treated; in addition, the composition has good therapeutic effect, no toxic and side effects, simple preparation and low cost.

The invention relates to a Callicarpa kwangtungensis Chun extract. The invention discloses that a total extract of Callicarpa kwangtungensis Chun and a phenylethanol glycoside compound enriched from the total extract of Callicarpa kwangtungensis Chun through a macroporous resin column have an anti-myocardial ischemia effect. This part can always play a role in protecting rat myocardial damage by reducing the content of LDH, CK and MDA in serum, increasing the content of GSH in myocardial tissue, increasing the activity of Na<+> / K<+>-ATPase in myocardial tissue and reducing the level of inflammation and apoptosis. Total phenylethanoid glycoside of Callicarpa kwangtungensis Chun exerts the myocardial protection effect through Na<+> / K<+>-ATPase / Src / ERK1 / 2 signaling pathway.

The invention relates to an anti-cervicitis tablet and a preparation technology thereof. The preparation technology comprises the following steps: providing raw materials: 300 to 310 parts by weight of callicarpae caulis et folium dry extract, 80 to 85 parts by weight of herba leonuri dry extract, 70 to 75 parts by weight of radix linderae dry extract, 60 to 65 parts by weight of a filler, 2 to 3parts by weight of magnesium stearate and proper amount of a wetting agent; crushing, uniformly mixing and sieving the callicarpae caulis et folium dry extract, the radix linderae dry extract, the herba leonuri dry extract and the filler to obtain a first mixture; mixing the first mixture with the wetting agent, carrying out spraying granulation and drying to obtain dry particles; granulating thedry particles, adding the magnesium stearate while granulating and tabletting to obtain the anti-cervicitis tablet. The preparation technology can obviously improve the humidity resistance of a product.

The invention discloses a traditional Chinese medicine composition for treating chronic gastritis. The traditional Chinese medicine composition is prepared from, by weight, 15-29 parts of picria fel-terrae lour, 9-21 parts of callicarpa kwangtungensis, 4-17 parts of bunge corydalis herbs, 5-17 parts of flos lonicerae, 9-25 parts of rhizoma dioscoreae hypoglaucae, 10-24 parts of natural borneol, 8-19 parts of snake gall, 6-18 parts of glabrous sarcandra herbs, 9-20 parts of andrographis paniculata and 5-20 parts of hedyotis hedyotidea. The traditional Chinese medicine composition is capable of tonifying middle-jiao and qi, smoothing the liver, regulating vital energy, tonifying the spleen, nourishing the stomach, dispelling dampness and hotness and restoring gastric mucosa, and thereby chronic gastritis is cured fundamentally.

The invention provides a Callicarpa kwangtungensis chun. essential oil extract, which is characterized by comprising 1.2-2.9% of aliphatic acid compound and 45.0-55.0% terpene component. The invention also provides a preparation method of the Callicarpa kwangtungensis chun. essential oil extract, a pharmaceutical composition containing the Callicarpa kwangtungensis chun. essential oil extract, and an application.

The present invention discloses a callicarpa kwangtungensis extract-containing medicine for treating sphagitis and relates to the field of medicines. The callicarpa kwangtungensis extract-containing medicine for treating the sphagitis comprises the following components in parts by weight: 5-8 parts of a callicarpa kwangtungensis extract, 45-60 parts of pregelatinized starch, 8-12 parts of sodium carboxymethyl cellulose and 15-25 parts of magnesium stearate. The callicarpa kwangtungensis extract-containing medicine can act directly on lesions, has a synergistic effect on viruses and bacteria, treats both cause and symptoms, has a good effect on treatment of the sphagitis, and is free of toxic and side effects.

The invention discloses a traditional Chinese medicine for treating diabetes mellitus and a preparation method thereof. The traditional Chinese medicine is prepared from Indian adenosma herb, medulla helwingiae, folium turpiniae, callicarpa kwangtungensis, zedoary, polygonum sinense, malva verticillata, glechoma longituba and deep-fried atractylodes macrocephala koidz. The traditional Chinese medicine is reasonable in recipe, safe and convenient to take, free of toxic or side effect, and definite and remarkable in curative effect through clinical verifications. As indicated by clinical observation for many years, the traditional Chinese medicine prepared through the preparation method disclosed by the invention can obviously improve the symptoms of polydipsia, dieresis, polyphagia, emaciation and fatigue and lack of strength caused by diabetes mellitus and has a remarkable effect on reducing blood glucose.