134results about How to "Long-term storage stability" patented technology

An antibody-containing solution formulation comprising an organic acid and a surfactant as stabilizers; a method for suppressing the formation of visible insoluble matter and / or insoluble particles due to the presence of metal ions in an antibody-containing solution formulation, which comprises adding an organic acid to the solution; a method for suppressing the formation of visible insoluble matter and / or insoluble particles during shaking and freezing-thawing of an antibody-containing solution, which comprises adding a surfactant to the solution; and a method for stabilizing an antibody-containing solution, which comprises adding an organic acid and a surfactant.

Amine solubilizing agents are mixed with water insoluble defoamers and optionally a dispersant for cementitious compositions to provide an admixture for cementitious compositions that is stable over time. A cementitious composition is provided that includes cementitious material, water, a water insoluble defoamer, optionally a dispersant for cementitious compositions, and an amine solubilizing agent that solubilizes the water insoluble defoamer. A method is provided for making a cementitious composition that includes mixing cementitious material, water, a water insoluble defoamer, an amine solubilizing agent that solubilizes the water insoluble defoamer, and optionally a dispersant for cementitious compositions.

The invention relates to a cosmetic composition for application to the skin, having:a) 0.05 to 0.5% by weight of a quaternized polysaccharide, 0.05 to 5.0% by weight of a polyethylene glycol derivative or polypropylene glycol derivative and / or 0.05 to 3% by weight of a polymeric quaternized ammonium compound (“polyquaternium”),b) 10 to 40% by weight of oils and / or oil-like constituents, andc) 0.2 to 15% by weight of an ester quat and / or of a dialkyl quat.

The present invention aims to provide an ink for ink jet recording that is excellent in storage stability and discharge stability and attains high coloration on regular paper or gloss paper and high glossiness on gloss paper. The ink for ink jet recording of the invention includes: water; and a pigment dispersed by using a polymer which is obtained by polymerizing at least 50% by weight or more of benzylacrylate and 15% by weight or less of (meth)acrylic acid as components of the polymer and has an acid value of no less than 50 mgKOH / g and no more than 120 mgKOH / g and a weight average molecular weight of no less than 10000 and no more than 120000.

The present invention relates to a preparation method of film electrode component for protein exchange film fuel cell. The catalyst slurry prepared by using low boiling point and low viscosity alcohol as dispering agent and using high boiling point and high viscosity alcohol as stabilizing agent can be directly coated on the surface of conductive film. The proton conductive film premoistened by high boiling point and high viscosity alcohol can not be deformed, after the catalyst slurry is coated on it, and can form the invented film electrode component with uniform, continuous and high-activecatalyst layer.

Transdermal drug delivery patches and methods of their production are described. The patches can be made such that the accommodate highly plasticizing drugs such as selegiline and / or the use of protonated forms of various drugs.

Transdermal drug delivery patches and methods of their production are described. The patches can be made such that the accommodate highly plasticizing drugs such as selegiline and / or the use of protonated forms of various drugs.

The invention discloses a preparation method of a H-grade water-solubility silicon steel sheet paint, which comprises the following steps of: taking raw materials such as 10-20 parts of plant oil, 5-10 parts of polyatomic alcohol, 5 parts of binary acid, 3 parts of trimellitic anhydride, 5 parts of cosolvent, 3 parts of neutralizer, 0.5 part of coupling agent, 30 parts of alcohol, 25 parts of nanometer inorganic packing, 0.15 part of pigment, 5 parts of melamine resin, 0.1 part of flatting agent, 2 parts of dispersing moistening agent, 0.1 part of deforming agent and 10 parts of water according to a weight ratio, and preparing an environmental-friendly product with good combination properties for large generators through the synthesis of alkyd resins, the coupling treatment of the nanometer inorganic packing, the mixing and dispersion of materials such as the inorganic substances and the like in a paint, the grinding of the paint vehicle and the like. The preparation method has the advantages of solving the problems of sedimentation, aggregation and blocking of powder in paint liquid under the condition of high content of inorganic powder, obviously increasing the storage stability of the paint liquid and the hardness of a paint film, effectively reducing the discharge of poisonous and harmful gases in the production process and reducing the harm to the health of human bodies.

The purpose of the present invention is to provide a foam-forming aerosol product that can be applied with a high degree of safety regardless of the usage environment, that has excellent storage stability, and that is capable of easily forming a satisfactory foam. This foam-forming aerosol product is characterized by being provided with a double-structure container provided with a discharge mechanism having a propellant filling space and two stock liquid filling spaces, the discharge mechanism for simultaneously discharging contents filled into the two stock liquid filling spaces, a propellant comprising a compressed gas being filled into the propellant filling space, a first stock liquid composition containing 0.5-15.0% by mass of an organic acid being filled into a first stock liquid filling space, a second stock liquid composition containing 0.5-15.0% by mass of a bicarbonate substance being filled into a second stock liquid filling space, and a foam being formed by mixing of the first stock liquid composition discharged from the first stock liquid filling space and the second stock liquid composition discharged from the second stock liquid filling space.

The invention provides a dealcoholization type double-component silica gel. The dealcoholization type double-component silica gel comprises a component A and a component B at the mass ratio of 100:(0.01-2); the component A comprises 100 parts by weight of polydimethylsiloxane, 0-10 parts by weight of a hardness regulator, 0.3-12 parts by weight of a crosslinking agent, and 0.01-0.5 parts by weightof a tackifier; the component B comprises 0.01-2 parts by weight of a catalyst; the crosslinking agent is chosen from an organosilicon compound with a general formula as shown in a formula (I), a lowpolymer of the organosilicon compound with the general formula as shown in the formula (I), or an organosilicon compound as shown in a formula (II), R1, R2, R3, R4, R6 and R7 in the formula are independently chosen from monovalent hydrocarbon radical; R5 is bivalent hydrocarbon radical, the number of carbon atoms of the bivalent hydrocarbon radical is 2-20; a is equal to 0 or 1, b is equal to 0 or 1, and c is equal to 0 or 1. The dealcoholization type double-component silica gel uses the components at the specific contents, the relatively good interaction is achieved; the adhesive property, the durability, the airtightness and the long-term storage stability of a product are excellent at the same time; and the deep solidifying performance is excellent.

Compositions and methods are provided for treatment growth hormone and / or insulin-like growth factor 1 deficiency in a patient in need of such treatment. Compositions and methods include novel vaccines that provide immunogenicity for somatostatin and result in the increased release of endogenously produced growth hormone and / or insulin-like growth factor 1.

A dispersion which contains a dispersant and particles selected from among metal particles and metal oxide particles, and which is characterized in that: the dispersant has a chemical structure that is able to be bonded or adsorbed to the particles; and the dispersant contains a low-molecular-weight dispersant that has at least one peak within a molecular weight region of 31 or more but less than 1,000 in the molecular weight distribution curve in terms of polyethylene glycol as determined by gel permeation chromatography and a high-molecular-weight dispersant that has at least one peak within a molecular weight region of 1,000 or more but 40,000 or less in the above-described molecular weight distribution curve.

The invention discloses carboxymethyl dextrin / chitosan composite nanogel as well as a preparation method and application thereof. The preparation method of the carboxymethyl dextrin / chitosan compositenanogel comprises the following steps: electrostatically complexing carboxymethyl dextrin and chitosan to form the carboxymethyl dextrin and chitosan composite nanogel. The preparation method of O / Wpickering emulsion comprises the following steps: uniformly mixing an oil phase and the carboxymethyl dextrin / chitosan composite nanogel by adopting a high pressure homogenization technique to obtainthe O / W pickering emulsion. The pickering emulsion prepared by the invention has good emulsification performance, and colloidal particles can be irreversibly absorbed and anchored on an oil / water interface to form a compact layer, so that the steric-hinerance effect is improved, thereby improving the stability of the emulsion, significantly improving the agglomeration resistance and Ostwald curingcapability of the emulsion, having long-term storage stability, and having wide application in the fields of food, medicine, cosmetics and the like.

The invention discloses a bifunctional starch-based composite nanoparticle as well as a preparation method and an application thereof. The preparation method comprises the following steps: hydrolyzingstarch to form linear dextrin, and grading the linear dextrin by adopting an alcohol-alcohol gradient precipitation method to obtain linear dextrin with uniform molecular weight distribution; carrying out oxidation treatment on the linear dextrin through an oxidation system to obtain oxidized dextrin; carrying out complexation reaction on the oxidized dextrin and curcumin to form an oxidized dextrin-curcumin complex, so that the oxidized dextrin-curcumin / chitosan hydrochloride composite nanoparticles and chitosan hydrochloride form the oxidized dextrin-curcumin / chitosan hydrochloride composite nanoparticles. According to the method, the aqueous phase solution of the bifunctional starch-based composite nanoparticles containing the gellan is uniformly mixed with the primary emulsion, the obtained double emulsion is subjected to calcium ion induction treatment to obtain the double emulsion gel, and the double emulsion gel has good oxidation resistance and long-term storage stability andcan be applied to the fields of protection of nutritional ingredients, drug delivery, preparation of cosmetics and the like.

Production of solid medicaments (A) containing vardenafil hydrochoride (I) in the form of the trihydrate involves using (I) of any water content in the production of (A) and converting (I) into the trihydrate form at an intermediate processing stage or in the final product. An independent claim is included for the medicaments (A) (specifically in coated tablet form) obtained by the process. - ACTIVITY : Vasotropic. - MECHANISM OF ACTION : None given in the source material.

An MMA (methyl methacrylate)-based colored anti-slip thin-layer paving material is prepared from, by mass, 28-42% of modified methyl methacrylate, 6-12% of n-butyl methacrylate, 2.5-5% of isooctyl acrylate, 3.2-5.5% of fumed silica, 1.5-3.2% of styrene, 1.2-2.3% of high-boiling-point paraffin, 2.1-3.6% of a two-functional-group ethylene-propenyl composite dispersing agent, 8-10% of calcium or magnesium filler, 15-24% of high-hardness natural mineral filler, 0.5-0.85% of N-N-dimethyl p-hydroxyaniline, 0.8-2.8% of a cross-linking agent BPO and 2.5-4.5% of resin based color paste, wherein N-N-dimethyl p-hydroxyaniline and the cross-linking agent BPO are reaction excitation substances. The invention provides a preparation process of the MMA-based colored anti-slip thin-layer paving material. The material is long in stable storage period, quick, convenient and simple in construction, high in adhesion with base planes, environmental friendly, safe, resistant to pollution and chemical corrosion, easy to clean and excellent in physical and chemical performance, has a rich color system and realizes better combination of comfort and slip resistance.

A method of treating an individual with a condition which condition is one wherein the individual with the condition benefits from the administration of GnRH and / or a GnRH analogue, the method comprising administering to the individual GnRH and / or a GnRH analogue and an inhibitor of prostaglandin synthesis and / or a prostaglandin receptor antagonist. The methods of the invention also include combating a sex-hormone dependent disease in an individual, and regulating fertility in an individual.

A fabric conditioning composition comprises (a) from 7.5 to 80% by weight of a ester-linked quaternary ammonium fabric softening material comprising at least one mono-ester linked component and at least one tri-ester linked component, (b) an inorganic electrolyte and a (c) fatty complexing agent wherein the parent fatty acids or fatty acyl compounds from which component (a) is formed have an iodine value of from 0 to 4.

The invention discloses a composition, rigid polyurethane foam and a refrigeration device. The composition comprises combined polyether and isocyanate, wherein the combined polyether contains polyol, a foaming agent and a catalyst composition, wherein the foaming agent contains trans-1-chloro-3, 3, 3-trifluoropropene, and the catalyst composition contains N-methyldicyclohexylamine, N, N-dimethylcyclohexylamine and (2-hydroxypropyl) trimethylammonium formate. The composition has long-term storage stability; and furthermore, the foam material obtained by adopting the composition has the characteristics of low heat conduction coefficient, high strength, short curing time and the like, so that an obtained product has a relatively good energy-saving effect.

The invention belongs to the technical field of energy storage fuel and particularly relates to high-energy nano energy storage fuel capable of meeting the use of a missile weapon and a preparation method thereof. The energy storage fuel comprises the following components in percentage by weight: 3-30 percent of nano Al powder, 5-90 percent of liquid hydrocarbon fuel and 7-90 percent of carborane,wherein the nano Al powder is spherical and has an average particle size of less than 150 nm and an active Al content of higher than 90 percent; the liquid hydrocarbon fuel is a petroleum rectification product or synthetic hydrocarbon or two types of compositions. The nano energy storage fuel provided by the invention is high in energy, excellent ignition and combustion performances, simple in preparation method and excellent in sedimentation resistance.

A particulate lipid pharmaceutical composition comprises a particulate solid non-lipid carrier and an oil-in-water emulsion on the carrier. The emulsion comprises a dissolved or dispersed pharmacologically active agent. The oil-in-water emulsion is released from the carrier on contact with an aqueous media to form an oil-in-water emulsion in the media. Also disclosed is a method of producing the composition and a tablet containing it; sachets and capsules filled with the composition; use of the composition and the tablet as a medicine; a method of administering the composition to a patient.

The invention provides particulate detergent compositions containing alkaline peroxide salts and organic peracid precursors, methods of treating stains with these compositions and methods of making the compositions. The compositions have long term storage stability imparted by a coating to the alkaline peroxide salt. The methods of formulating the compositions to include this coating are relatively easy and inexpensive.

The invention discloses a plant oil emulsifying emulsifier composition. In percent by weight, the plant oil emulsifying emulsifier composition comprises 5-25% of fatty acid ester or alkyl benzenesulfonic acid and 75-95% of maleic anhydride modified plant oil or a reaction product of the maleic anhydride modified plant oil and polyether. The invention further discloses a preparation method of the plant oil emulsifying emulsifier composition. The plant oil emulsifying emulsifier composition has a good plant oil emulsifying effect, and obtained self-emulsified plant oil has long-term storage stability and excellent emulsifying performance; meanwhile, as a tank mixing aid, the self-emulsified plant oil formed by mixing the plant oil emulsifying emulsifier composition and the plant oil can increase the fogdrop particle size, reduce spray drift, dissolve wax layers on the surfaces of a target and a target crop, improve the penetration rate of a pesticide on the target or a target plant, enhance the bactericidal effect and increase the cation density, and facilitates deposition of the pesticide on the target.

The invention discloses a method for preparing efficient and stable inorganic perovskite quantum dots by using a double-layer ligand. The method comprises the following steps of: adding lead halide, didodecyl dimethyl ammonium bromide, organic amine, octadecene, tert-butylbenzene and cesium 4-dodecylbenzene sulfonate into a hydrothermal reaction kettle under high temperature and high pressure, carrying out hydrothermal reaction to obtain an inorganic perovskite quantum dot solution, adding ethyl acetate into the perovskite quantum dot solution, performing purifying, conducting centrifuging toremove the supernatant, and dispersing the precipitate in methylbenzene, and collecting a methylbenzene solution of the perovskite quantum dots to obtain a high-stability inorganic perovskite quantumdot methylbenzene solution. According to the invention, a double-shell layer is formed on the surface of the perovskite nanocrystal to serve as a protective layer by utilizing a double-ligand synergistic effect, so that the storage and humidity stability of the perovskite nanocrystal can be improved, and the prepared perovskite quantum dots are high in quantum efficiency, high in stability and suitable for the field of nuclear batteries.

A stable G-CSF formulation containing one or more amino acids selected from the group consisting of lysine, histidine, arginine, aspartic acid, glutamic acid, threonine and asparagine; one or more amino acids selected from hydrophobic amino acids; and methionine. A method for inhibiting the formation of the methionine residue-oxidized derivative of a physiologically active protein having methionine residues characterized by adding methionine to a composition containing this protein.

The invention provides a dealcoholized silicone rubber sealant. The dealcoholized silicone rubber sealant comprises the following components: 100 parts of polydimethylsiloxane, 20 to 200 parts of calcium carbonate, 2 to 12 parts of a silicone crosslinking agent, 0.05 to 8 parts of a catalyst, and 0. 05 part to 5 parts of a tackifier all in parts by weight; the tackifier is prepared from an amino coupling agent, an epoxy coupling agent, and a polyisocyanate compound. Compared with the prior art, the dealcoholized silicone rubber sealant provided by the invention adopts the specific tackifier, and cooperates with other specific content components to achieve better interaction, so that the product has better greenhouse curing performances, long-term storage stability, excellent adhesion and good adhesion durability. Experimental results show that the dealcoholized silicone rubber sealant provided by the invention has good adhesion to all materials of metal, various plastic, ceramic, glassand the like, and can be used for sealing photovoltaic components, buildings, automobiles, electronic appliances and the like.