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Degradable material for disposable uterine probe

A technology for degrading materials and probes, applied in medical science, surgery, etc., can solve problems such as damage to human health, large usage, inability to combine degradation, corrosion resistance and antibacterial at the same time, and achieve good compatibility and degradation performance. Good results

Active Publication Date: 2018-12-07
台州市中心医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, plastic disposable uterine probes are commonly used consumables in gynecology, and the amount of use is also very large, which will involve the problem of centralized disposal after use. It leads to environmental pollution and damage to human health, and in order to solve the problem of non-degradability, the existing one-time degradable materials are also used, such as a degradable disposable uterine probe disclosed in Chinese patent (authorized announcement number: 102727940B) Needles machined from polylactic acid, reinforcement and lubricant composite
However, it only considers the degradability of the material, and due to the influence of the application environment of the uterine probe, it may be affected by the environment such as uric acid during use, so it must have good corrosion resistance and material durability. Antibacterial properties, that is, the existing properties that cannot simultaneously degrade, corrosion resistance and antibacterial properties

Method used

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  • Degradable material for disposable uterine probe

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The degradable material used for the uterine probe in this embodiment includes parts by weight of the following components:

[0019] Glycidyl methacrylate grafted poly-L-lactic acid: 78; polycaprolactone: 25; lubricant ethylene bisstearamide: 3.0; modifier with core-shell structure: 4.0, the shell of the modifier It is a mixture of poly D-lactic acid and polyisoprene, here, the mass ratio of poly D-lactic acid and polyisoprene is 1:3, the core layer is sodium alginate and oligomeric chitosan, and alginic acid Sodium accounts for 4.0% of the mass of the modifier; oligochitosan accounts for 0.5% of the mass of the modifier, and the molecular weight of the oligochitosan is 5000Da.

[0020] The manufacturing method of the disposable uterine probe can be processed by conventional methods in the art, and the specific preparation method in this embodiment is as follows:

[0021] Select the raw materials according to the weight ratio of the ingredients in the above formula, ad...

Embodiment 2

[0023] The degradable material used for the uterine probe in this embodiment includes parts by weight of the following components:

[0024] Glycidyl methacrylate grafted poly-L-lactic acid: 75; polycaprolactone: 25; lubricant ethylene bisstearamide: 4.0; modifier with core-shell structure: 5.0, shell layer of modifier It is a mixture of poly D-lactic acid and polyisoprene, here, the mass ratio of poly D-lactic acid and polyisoprene is 1:3.5, the core layer is sodium alginate and oligomeric chitosan, and alginic acid Sodium accounts for 6.0% of the mass of the modifier; oligochitosan accounts for 0.8% of the mass of the modifier, and the molecular weight of the oligochitosan is 6000Da.

[0025] The manufacturing method of the disposable uterine probe is consistent with that of Embodiment 1, and will not be repeated here.

Embodiment 3

[0027] The degradable material used for the uterine probe in this embodiment includes parts by weight of the following components:

[0028] Glycidyl methacrylate grafted poly-L-lactic acid: 76; polycaprolactone: 23; lubricant ethylene bisstearamide: 35; modifier with core-shell structure: 4.5, the shell layer of the modifier It is a mixture of poly D-lactic acid and polyisoprene, here, the mass ratio of poly D-lactic acid and polyisoprene is 1:3, the core layer is sodium alginate and oligomeric chitosan, and alginic acid Sodium accounts for 5.0% of the mass of the modifier; oligochitosan accounts for 0.6% of the mass of the modifier, and the molecular weight of the oligochitosan is 5500Da.

[0029] The manufacturing method of the disposable uterine probe is consistent with that of Embodiment 1, and will not be repeated here.

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Abstract

The invention relates to a degradable material for a disposable uterine probe, and belongs to the technical field of degradable medicinal materials. In order to solve the problem that an existing material cannot both have functions of corrosion resistance and bacteria resistance, the degradable material for the disposable uterine probe is provided. The material is prepared from the following components in parts by weight: 75 to 78 of grafted poly L-lactate, 21 to 25 of polycaprolactone, 3.0 to 4.0 of lubricant, and 4.0 to 5.0 of modifying agent having a core-shell structure, wherein a shell layer of the modifying agent is a mixture of the poly D-lactate and polyisoprene, a core layer is sodium alginate and chitosan oligosaccharide, and the sodium alginate accounts for 4.0 percent to 6.0 percent of the mass of the modifying agent; the chitosan oligosaccharide accounts for 0.5 percent to 0.8 percent of the mass of the modifying agent; and the grafted poly L-lactate is formed by graftingmolecules containing epoxy groups. According to the degradable material, the performance effects of good degradation performance, high corrosion resistance and bacterial inhibition are achieved overall.

Description

technical field [0001] The invention relates to a degradable material used for a disposable uterine probe, belonging to the technical field of degradable medical materials. Background technique [0002] Uterine probe is a commonly used gynecological examination instrument in gynecological examination. With the continuous development of medical technology, the current use of uterine probe is basically a disposable uterine probe to prevent cross-infection and improve the safety and health requirements of use. . However, plastic disposable uterine probes are commonly used consumables in gynecology, and the amount of use is also very large, which will involve the problem of centralized disposal after use. It leads to environmental pollution and damage to human health, and in order to solve the problem of non-degradability, the existing one-time degradable materials are also used, such as a degradable disposable uterine probe disclosed in Chinese patent (authorized announcement ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/06A61L31/04A61L31/14A61L31/16
CPCA61L31/042A61L31/048A61L31/06A61L31/14A61L31/148A61L31/16A61L2300/232A61L2300/236A61L2300/404C08L67/04C08L47/00C08L5/04C08L5/08
Inventor 瞿向东
Owner 台州市中心医院
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