Beam shaping body for neutron capturing treatment

Abstract

The invention provides a beam shaping body which can be used in a neutron capturing system to change the irradiation range of neutron beams. The beam shaping body comprises a beam inlet, a target material, a deceleration body adjacent to the material body, a reflector surrounding the outside of the deceleration body, a thermal neutron absorber adjacent to the deceleration body, a radiation shieldarranged in the beam shaping body and a beam outlet. The target material makes nuclear reaction with a proton beam input via the beam inlet to generate neutrons, the neutrons form a neutron beam, theneutron beam limits one main axis, the deceleration body decelerates the neutrons generated from the target material to an epithermal neutron energy zone, the reflector guides neutrons deviated from the main axis back to the main axis to gather epithermal neutrons, the thermal neutron absorber absorbs thermal neutrons to avoid excessive dosage in normal superficial tissues during treatment, the radiation shield shields leaked neutrons and photons to reduce the normal tissue dosage in a non-irradiation area, and the beam shaping body further comprises a replacement member which can be mounted or dismounted in / from the shaping body to change the irradiation range of the neutron beam.

Description

technical field [0001] The invention relates to a beam shaping body, in particular to a beam shaping body for neutron capture therapy. Background technique [0002] With the development of atomic science, radiation therapy such as cobalt 60, linear accelerator, and electron beam has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment for more radioresistant malignant tumors (eg glioblastoma multiforme, melanoma) is often less effective. [0003] In order to reduce radiation damage to normal tissues around the tumor, the concept of target therapy in chemotherapy (chemotherapy) has been applied to radiation therapy; and for tumor cells with high ra...

AI Technical Summary

Problems solved by technology

[0005] Because the effectiveness of boron neutron capture therapy depends on the concentration of boron-containing drugs and the number of thermal neutrons at the tumor cell location, it is also called binary cancer therapy; the beam used in the existing AB-BNCT facility The shaper usually adopts various collimators with different apertures to adjust the size of the neutron beam. However, in the case of no collimator, the beam exit is composed of a reflector and a neutron shield, so only relying on The collimator restricts the beam exit, and the variable range of the beam exit is limited

For example, when the beam exit radius of the beam shaper without a collimator is 7 cm, and the tumor area is large, the tumor area cannot be completely irradiated due to the small irradiation range of the beam; The beam exit radius of the beam shaper of the beam shaping body is 10 cm, and when the tumor area is small, even if a collimator is added, the collimator is limited by its thickness, and the radiation range of the beam is too large to be effective. Limiting the beam irradiation area, resulting in unnecessary irradiation of surrounding normal tissues

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