Natural enemy mew audio induction anxiety animal model construction method and application

A technology of animal models and construction methods, applied in animal husbandry, etc., can solve problems such as difficulty in achieving control levels, difficulties in rodent experiments, and easy influence on other experiments, achieving high accuracy, significant effects, and solving the effects of cumbersome production
CN109258573AInactive Publication Date: 2019-01-25WUZHOU UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
WUZHOU UNIV
Publication Date
2019-01-25
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a natural enemy mew audio induction anxiety animal model construction method. Natural enemy mew audio frequencies are broadcast within the hearing domain of an experiment mousethrough an audio player, and an anxiety animal model is induced; while the natural enemy mew audio frequencies are played or within follow-up seven days, animal behavior testing is performed on the experiment mouse to evaluate the anxiety behavior. The invention further discloses application of the anxiety animal model obtained through the construction method for screening anti-anxiety drugs. Thenatural enemy mew audio induction anxiety animal model is remarkable in effect, convenient to use and safe, the obtained experiment result is high in accuracy, and the method can be used for screening the anxiety drugs and evaluating and treating the anxiety disorder.
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Description

technical field

[0001] The invention belongs to a construction method and application of an animal model, in particular to a construction method and application of an anxiety animal model induced by a natural enemy meowing audio. Background technique

[0002] Anxiety disorders are a type of mental illness characterized by episodic or persistent emotional anxiety, accompanied by symptoms such as autonomic disturbance, muscle tension, and restlessness in movement. In recent years, with the increasingly fierce social competition and the increasing pressure of life, the incidence of anxiety disorders has increased year by year, and has become one of the main mental diseases that affect people's quality of life, bringing a heavy burden to patients' families and society. The etiology of anxiety disorders is still unclear, and anxiolytic drugs are limited in clinical practice due to many adverse reactions. Therefore, anxiety disorders and new anti-anxiety drugs have become the foc...

Claims

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