an n-b 18 h 22 Preparation method and application of inclusion complex with cyclodextrin
A technology of n-b18h22 and cyclodextrin, which is applied in the field of preparation of inclusion compounds, can solve the problems of low solubility, influence property research and related applications, unstable properties, etc., and achieve the effect of improving stability
Inactive Publication Date: 2020-04-07
SOUTH CHINA NORMAL UNIVERSITY
View PDF2 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
But n-B 18 h 22 The solubility in aqueous solution is small and easy to hydrolyze, and its properties are unstable, which seriously affects its property research and related applications in aqueous solution.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1n-B18H22
[0034] Example 1n-B 18 h 22 Preparation method of inclusion compound with cyclodextrin
[0035] 1, the preparation method of the present invention comprises the following steps:
[0036] 1) Respectively call n-B 18 h 22 and cyclodextrin; weighed n-B 18 h 22 The molar ratio with cyclodextrin is 1:1;
[0037] 2) Mix n-B with solvent 18 h 22 Dissolved to obtain n-B 18 h 22 solution;
[0038] 3) preparing a saturated aqueous solution of cyclodextrin;
[0039] 4) the n-B prepared in step 2) 18 h 22 Add the solution into a saturated solution of cyclodextrin and stir until uniform, refrigerate for 12 hours, a turbid yellow solid appears; dry it in vacuum to obtain the inclusion product.
[0040] In some embodiments, in step 1), the cyclodextrin includes β-cyclodextrin or γ-cyclodextrin.
[0041] In some embodiments, in step 2), the solvent is acetonitrile.
[0042] In some embodiments, in step 2), acetonitrile and n-B 18 h 22 The dosage is: Dissolve 0.0388g of n-B p...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention relates to the technical field of preparation of coated chemical materials, in particular to a preparation method and application of an inclusion complex of n-B18H22 and cyclodextrin. The method comprises the following steps: weighing the n-B18H22 and cyclodextrin; preparing an n-B18H22 acetonitrile solution; preparing a cyclodextrin saturated aqueous solution; adding the n-B18H22 acetonitrile solution into the cyclodextrin saturated aqueous solution, stirring until the solution is uniform, and refrigerating the solution for 12 hours till a turbid yellow solid appears; and performing suction filtering and drying in vacuum to obtain the inclusion complex product. The saturated product of the invention can be applied to transferring in the aqueous solution, fluorescent labelingand related reactions (such as preparation of derivatives thereof) and the like. The inclusion complex disclosed by the invention inhibits the hydrolysis of n-B18H22, and the stability in the aqueoussolution is greatly improved. When beta-CD and n-B18H22 coexist, light absorption of n-B18H22 is not interfered. A new way is developed for research and application of the n-B18H22 in the aqueous solution.
Description
technical field [0001] The invention relates to the technical field of preparation of packaged chemical materials, in particular to a n-B 18 h 22 Preparation method and application of clathrate with cyclodextrin. Background technique [0002] In 1912, German chemist Stock used vacuum technology to synthesize butaborane during the preparation process, which laid the foundation for the development of borane chemistry. Due to the special physical and chemical properties of borane materials, more and more researchers have devoted themselves to the research on the preparation and performance of new functional borane materials. In recent years, octadecaborane has received a lot of attention as a new type of borane material. Octadecaborane has two isomers, namely n-B 18 h 22 and i-B 18 h 22 , due to their unique symmetric structure ( figure 1 ) and high boron content make it have many potential applications in medicine and new materials. In February 2015, Czech scientists ...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/16
CPCC08B37/0015
Inventor 谭春华张宝凯张林娜陈洁
Owner SOUTH CHINA NORMAL UNIVERSITY