1302 results about "Acetonitriles" patented technology

The invention relates to a preparation method and application of a porous material for preparing methanol through carbon dioxide adsorption and conversion. When the material is prepared, firstly, 4, 4 '4' '-(1, 3, 5-triazine-2, 4, 6-trimethylene) triphenylamine and 1, 2-acenaphthequinone are treated in a mixed solvent containing dioxane / acetonitrile / 6M acetic acid, and AT-COF is obtained; further synthesizing by adopting an impregnation method to obtain IrRu-COF; and finally, uniformly mixing the active gamma-aluminum oxide and the IrRu-COF material to form a carrier dispersion liquid, and then carrying out PEI loading, vacuum impregnation, washing and drying to obtain the PEI functionalized gamma-Al2O3 / COF composite catalyst. The technical closed loop from low-concentration CO2 capture to solar driven conversion is realized, the process flow is simple, and the energy consumption is low.

The invention relates to the field of pharmaceutical analytical chemistry, in particular to a method for determining tandospirone and salt intermediates thereof, high performance liquid chromatography is adopted, and chromatographic conditions include that a chromatographic column with octadecylsilane chemically bonded silica as a filler is adopted, and gradient elution is performed by a mobile phase A and a mobile phase B; wherein the mobile phase A consists of a first water phase and acetonitrile; the mobile phase B is composed of a second water phase and acetonitrile; the first water phase is a water solution containing monopotassium phosphate and sodium hexanesulfonate, and the pH value of the first water phase is 3.0-3.8; the second water phase is an aqueous solution containing monopotassium phosphate and sodium hexanesulfonate, and the pH value of the second water phase is 1.8-2.6. The testing method disclosed by the invention has good specificity, accuracy and repeatability, and can be used for monitoring the quality of the tandospirone raw material medicine.

The invention discloses a preparation method of a modified zinc-bromine flow battery carbon felt negative electrode and the carbon felt negative electrode prepared by the method, and belongs to the field of zinc-bromine flow batteries. According to the method, after the carbon felt is soaked in a mixed solution of cuprous sulfate, water and acetonitrile, the acetonitrile is gradually evaporated from the solution through heating, the cuprous sulfate is gradually subjected to disproportionation reaction, and the copper elementary substance generated by the disproportionation reaction of the cuprous sulfate is deposited on the surface of the carbon felt, so that the purpose of loading the modified carbon felt with the copper elementary substance is achieved. The copper elementary substance is relatively stable in chemical property and has good zinc affinity, and the copper elementary substance is loaded on the surface of the carbon felt, so that the overpotential of zinc nucleation can be reduced, and reaction active sites on the surface of the carbon felt are increased. Besides, relatively strong acting force exists between copper and zinc, so that uniform deposition / stripping of zinc in the charging and discharging process is facilitated, a more uniform zinc deposition layer is formed on the surface of the carbon felt, formation of zinc dendrites is reduced, and the electrochemical performance of the zinc-bromine flow battery is improved.

The invention discloses an ether polymerization inhibitor special for a butadiene extraction system and a preparation method of the ether polymerization inhibitor. The ether polymerization inhibitor comprises the following raw materials: a polymerization inhibitor intermediate, a solvent and a dispersing agent, the production process comprises the following steps: preparing a polymerization inhibitor intermediate, preparing a solvent, compounding, feeding and mixing, filtering, removing impurities and detecting. According to the method, firstly, a polymerization inhibitor 701 and diethylene glycol normal pressure etherification process is adopted, and beta-hydroxyethyl methyl ether is introduced to seal a terminal group, so that the power consumption is reduced, the generation of byproducts is inhibited, the solubility of an intermediate acetonitrile is improved to be greater than or equal to 30g / L, and the anti-interference performance is greatly enhanced; the solvent doped with a small amount of silane modified nano diatomite is prepared, impurities can be adsorbed, metal ions can be chelated, the dispersing agent can be assisted to be evenly distributed, the problems that a pure water solvent is single in function and the dispersing agent is prone to agglomeration are solved, and the polymerization inhibition efficiency and the stability of an extraction system are guaranteed.

The invention relates to preparation of a crystalline allyl covalent organic framework material and application research of the crystalline allyl covalent organic framework material in benzamide cyclization green photocatalytic conversion. The SF-COF material is prepared by adopting a step-by-step synthesis method. The preparation method comprises the following steps: synthesizing a COF precursor by taking 1, 3-benzenetricarboxaldehyde and p-aminophenylacetonitrile as raw materials, and preparing the allylation covalent organic framework material with the electronic push-pull effect from the COF precursor and 5, 5 ', 5'-(benzene-1, 3, 5-triyl) tri (thiophene-2-formaldehyde) through a solvothermal method. The material is applied to the field of photocatalytic organic conversion, and benzamide cyclization and conversion of derivatives of benzamide are achieved under irradiation of a blue light LED. The prepared SF-COF has the advantages of efficient charge separation and electron conduction performance, good structural stability and chemical stability and the like. And a catalyzed organic reaction substrate has the advantages of wide universality range, good cycle stability and the like, and shows excellent photocatalytic conversion capability.

The invention relates to the technical field of adhesives, and discloses an imidazolium ionic liquid and a preparation method and application thereof, the preparation method comprises the following steps: reacting omega-bromoalcohol with 1-(methoxymethyl) imidazole in acetonitrile, and washing with methyl tert-butyl ether to obtain a target ionic liquid precursor; and dissolving the product in acetonitrile, adding 4-trifluoromethyl phenyl isocyanate, and washing with methyl tert-butyl ether after the reaction is finished, thereby obtaining the target imidazolium ionic liquid. The imidazolium ionic liquid disclosed by the invention is applied to a PVB (Polyvinyl Butyral) adhesive, and the PVB adhesive shows excellent adhesion strength in a macroscopic adhesion performance test on the basis of multiple interactions, and particularly has excellent adhesion strength on aluminum. The obtained adhesive can be universally adapted to various substrates such as metal substrates and macromolecule substrates, and finally high-strength and high-durability intelligent adhesion performance is achieved.

The application discloses an indium-based oxide catalyst, which is prepared by the following method: step one, adding indium nitrate, isophthalic acid, DMF, acetonitrile, imidazole and nitric acid into a reaction kettle, reacting at 80 DEG C for 12 hours, then heating to 100 DEG C and reacting for 24 hours, washing with DMF and anhydrous ethanol respectively, and vacuum drying for 12 hours to obtain an In-MOF precursor; step two, keeping the In-MOF precursor under the condition of nitrogen atmosphere and 200-600 DEG C for 4 hours, and naturally cooling to room temperature to obtain the indium-based oxide catalyst. Most of the prepared indium-based oxide catalysts still retain the corresponding three-dimensional hierarchical porous framework structure of the original MOF; the indium-based oxide catalyst contains highly dispersed metal active sites inside, effectively reduces the aggregation of metal oxides or metal elements, and thus exhibits more excellent catalytic activity; the organic ligand isophthalic acid generates a large amount of carbon material through pyrolysis under an inert atmosphere, greatly improving the conductivity of the indium-based oxide catalyst.

The invention discloses a preparation method and application of a multimode luminescent cesium yttrium chloride lead-free perovskite luminescent material. In the specific synthesis process, firstly, precursor materials-cesium carbonate, yttrium carbonate and cerium acetate are dissolved in a mixed solution of glacial acetic acid and hydrochloric acid, and a precursor solution is obtained; then dissolving a certain amount of antimony acetate with acetonitrile to form an anti-solvent solution; and finally, adding the precursor solution into the anti-solvent solution to obtain the Sb / Ce double-doped cesium yttrium chloride lead-free perovskite luminescent material. During application, the Cs3YCl6 Sb and the Cs3YCl6 Sb / Ce luminescent materials are combined for use to form a pattern, and protected information can be decrypted through a specific excitation wavelength. According to the invention, the cesium yttrium chloride lead-free perovskite luminescent material capable of realizing multimode luminescence can be prepared in a short time.

The invention belongs to the technical field of organic synthesis, and provides a preparation method of a cationic lipid compound, which comprises the following steps: (1) reacting 1, 5-dihalopentane, 2-tert-butyl glycolate and alkali to obtain a product G; (2) hydrolyzing the product G under an acidic condition to obtain a product H; (3) carrying out esterification reaction on the product H, the raw material C, 4-dimethylaminopyridine and a condensing agent in dichloromethane to obtain a product J; and (4) carrying out amination reaction on the product J, the raw material L and alkali in acetonitrile to obtain the cationic lipid compound. Compared with the prior art, the method has the relatively remarkable advantages that when the first part of halogenated long-chain alkyl ester H is synthesized by the method, 1, 5-dihalopentane and 2-tert-butyl glycolate are used as raw materials, the halogenated long-chain alkyl ester J is synthesized by a simple method, the product is obtained at a higher yield in synthesis, and the method is suitable for kilogram-level production. The route synthesis only comprises four steps of chemical reactions, and is suitable for industrial production.

The invention provides an ultrathin aramid nanofiber-based composite solid electrolyte and a preparation method and application thereof, and belongs to the technical field of polymer electrolytes and metal secondary batteries, the method comprises the following steps: adding LLZTO into anhydrous acetonitrile, stirring, then carrying out ultrasonic dispersion, then adding PEO and LiTFSI, carrying out constant-temperature stirring treatment, and then carrying out vacuum drying to obtain the ultrathin aramid nanofiber-based composite solid electrolyte. A mixed electrolyte solution is obtained; a porous aramid nanofiber aerogel film is soaked in the mixed electrolyte solution, and a soaked aramid nanofiber-based composite solid electrolyte is obtained; and placing the impregnated aramid nanofiber-based composite solid electrolyte on a polytetrafluoroethylene film, and carrying out vacuum drying and stripping to obtain the ultrathin aramid nanofiber-based composite solid electrolyte. The problems that an existing solid electrolyte is poor in mechanical property, low in ionic conductivity and unstable in electrochemical performance can be solved.

The invention relates to the technical field of environmental monitoring, in particular to a method for determining two organophosphate compounds in water. The two organic phosphate ester compounds are tri-(2, 3-dibromopropyl)-phosphate ester and xylenol phosphate ester; the method comprises the following steps: 1, putting a water sample to be detected into a centrifugal tube, adding sodium chloride, uniformly mixing, adding acetonitrile as an extracting agent, uniformly mixing by vortex, standing for layering, and filtering supernatant liquid by a needle filter to obtain liquid to be detected; 2, mixing the prepared tri-(2, 3-dibromopropyl)-phosphate standard intermediate solution with the prepared xylenol phosphate standard intermediate solution, and diluting with acetone to obtain a standard working solution; the to-be-detected liquid obtained in the first step is placed in a liquid chromatography-triple quadrupole mass spectrometry combined system to be analyzed; the method provided by the invention can realize simultaneous determination of tri-(2, 3-dibromopropyl)-phosphate and xylenol phosphate, and fills the blank of combined detection of two specific organophosphate compounds in the prior art.

The invention discloses application of a carbon steel corrosion inhibitor based on combination of physical adsorption, chemical adsorption and hydrophobic barrier, and relates to the technical field of metal corrosion inhibition. The technical problem that a corrosion inhibitor in the prior art is low in corrosion inhibition efficiency in a high-temperature strong-acid environment is solved. The preparation method of the carbon steel corrosion inhibitor comprises the following steps: firstly, ultrasonically dissolving 4-aminopyridine to obtain a solution I; then, dropwise adding an isopropanol solution of 2, 3-epoxypropyltrimethylammonium chloride into the solution I according to a molar ratio of 1: 1, removing a solvent through a rotary evaporation method, washing with ethanol, centrifuging to obtain quaternized 4-aminopyridine, and drying the quaternized 4-aminopyridine; and finally, the dried quaternized 4-aminopyridine and bromododecane are added into acetonitrile for a reaction, diethyl ether is dropwise added into obtained reaction liquid for precipitation, and the quaternized 4-aminopyridine-bromododecane carbon steel corrosion inhibitor is obtained after drying. The prepared carbon steel corrosion inhibitor is high in corrosion inhibition efficiency in a high-temperature and strong-acid environment.

The invention discloses a method for determining bedaquiline fumarate clean verification target residues, and relates to the technical field of instrument analysis of chemical pharmacy. The method comprises the following steps: preparing a sample wiping solution; determining the content of bedaquiline fumarate in the sample wiping solution by adopting a liquid chromatography; chromatographic conditions are as follows: a chromatographic column is a VP-ODS C18 column; mobile phases: a potassium hexafluorophosphate aqueous solution and acetonitrile, wherein the concentration of the potassium hexafluorophosphate aqueous solution is 0.01-0.03 mol / L; the elution mode is isocratic elution; the flow rate is 1 ml / min to 2 ml / min; the column temperature is 28-32 DEG C; the method has good specificity and sensitivity for determination of bedaquiline fumarate cleaning verification target residues, is simple and convenient to operate, rapid in determination, simple and easy to implement, and overcomes the defects that TOC, chemical titration methods, conductivity methods, pH methods and the like which are commonly used at present do not have specificity.

The invention provides a method for measuring gamma-aminobutyric acid in tableted candies, which comprises the following steps: measuring gamma-aminobutyric acid in tableted candies by using HPLC-ELSD (High Performance Liquid Chromatography-Evaporative Light Scattering Detector) according to a volume ratio of acetonitrile to water of (50-70): (30-50) as a mobile phase; a chromatographic column is an amino column; a detector is ELSD, the temperature of a drift tube is 80-85 DEG C, and carrier gas is air. The detection method disclosed by the invention is strong in specificity, high in accuracy, strong in stability, good in repeatability and high in sensitivity, and compared with an existing derivation method, the method disclosed by the invention is simple, green and efficient, and can be used for effectively detecting the content of gamma-aminobutyric acid in the tabletted candies.

The invention relates to the technical field of chemical separation and purification, and discloses a method for separation and purification of taxadiene from tobacco and GC-MSMS quantitative detection.The method for separation and purification of taxadiene from tobacco comprises the following steps that S1, tobacco leaves are made into powder, an extracting agent is added, ultrasonic extraction is conducted for multiple times, and extract liquor is obtained; s2, evaporating the extract to dryness, adding an organic solvent, and dissolving to form a concentrated solution; s3, the concentrated solution is added into a silica gel column for gradient elution, and an extraction sample is obtained; and S4, evaporating the extracted sample to dryness, adding acetonitrile for dissolving, and carrying out secondary recrystallization to obtain purified taxadiene. According to the method, the efficiency and purity of separating the taxadiene from the tobacco are improved, and the taxadiene is accurately quantified.

The cooling crystallization production system comprises a crystallization unit, a product storage tank, a pipeline and a switching unit, the crystallization unit is composed of at least two parallel crystallizers, feeding ports of the crystallizers are connected with a discharging port of a distribution tank, and a discharging port of the distribution tank is connected with a discharging port of the product storage tank. Each crystallizer is a double-pipe heat exchanger, the shell pass of each crystallizer is a material flow path, and the tube pass of each crystallizer is a cold / hot medium flow path; the pipeline and switching unit is configured to selectively enable any crystallizer to be connected into a circulation loop, and in the circulation loop, materials circularly flow in the shell pass of the crystallizer through a circulation pump so as to achieve cooling crystallization. The crystallizer completing crystallization can be selectively switched to a discharging pipeline, and a heating medium is introduced into the tube pass of the crystallizer to melt crystals and then output the crystals into the product storage tank; compared with the prior art, a semi-continuous production mode is constructed, and the production cycle of unit products is shortened.

The invention relates to the field of lithium battery polyether-based electrolyte. The invention provides a polyether-based lithium battery electrolyte and a preparation method thereof. According to the preparation method, polyethylene oxide and bis (fluorosulfonyl) lithium imide are taken as main bodies, a dynamic polyether prepolymer and polyether shell layer aluminum oxide nano powder are combined, and the imine bond conversion rate, the median particle size D50, the content of an organic shell layer and the unit molar ratio of lithium salt to ethylene oxide are controlled; the method comprises the following steps: preparing slurry by using an anhydrous acetonitrile system, casting, drying in stages and post-curing to obtain a film-shaped or coating-shaped electrolyte, so that the water content is not higher than 500mg / kg, the total residual organic solvent content is not higher than 1000mg / kg, the viscosity and the thickness are controllable, and the residual epoxy value is promoted to be reduced; the problem that the viscosity and the purity are difficult to consider in film casting is solved; the method is suitable for large-scale preparation of the lithium battery electrolyte membrane.

The invention discloses a construction method and application of a protein fingerprint spectrum of Tilletia foetida teliospore. The method comprises the following steps: firstly, preparing immunomagnetic beads by using a monoclonal antibody for resisting Tilletia foetida teliospore, wherein the immunomagnetic beads are used for specifically enriching target teliospore in a wheat sample; then, the captured magnetic bead-teliospore compound is placed in a formic acid-acetonitrile solution and subjected to efficient cracking through steel ball grinding, and internal protein of the teliospore is released. The released protein is subjected to MALDI-TOF-MS analysis, so that a protein fingerprint spectrum of the protein is obtained, and a characteristic protein fingerprint spectrum database of the fungal spores is constructed. The rapid identification of the Tilletia foetida teliospore is realized by comparing and analyzing the mass spectrum of the sample to be detected and the self-established database. The detection time is shortened to be within 1 h, the sensitivity reaches up to 105 spores per gram of samples, and the method has the advantages of being simple, convenient, accurate and efficient and is particularly suitable for on-site rapid screening in the field of food quality safety.

The invention particularly relates to a phosphotungstic acid / amino-functionalized UiO-66 bifunctional catalyst as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving zircon salt, terephthalic acid and 2-aminoterephthalic acid in an organic solvent; adding a regulator acetic acid, and activating to prepare amino-functionalized UiO-66; and slowly dropwise adding a phosphotungstic acid acetonitrile solution into the amino-functionalized UiO-66 acetonitrile dispersion liquid, stirring and reacting at room temperature, and separating and drying to obtain the catalyst HPW at amino-functionalized UiO-66. The bifunctional catalyst (phosphotungstic acid / amino-functionalized UiO-66) is coordinated through an acid-base site at a lower temperature (170 DEG C vsgt; according to the present invention, the reaction is performed at the temperature of 200 DEG C, the formation of carbon deposition can be substantially inhibited at the low temperature, and the catalyst has characteristics of high catalytic activity after five cycles, extraordinary hydrothermal stability and chemical stability, can maintain the stability of the catalyst in the reaction environment with the existence of a small amount of water, and has good and broad application prospects.

The preparation method comprises the following steps: dissolving a compound 1 and a compound 2 in a certain volume of acetonitrile, adding HATU, and generating a crude product solution of the lefanacin at a certain temperature; and purifying the crude product solution of the lehanakine to obtain the high-purity lehanakine. The ratio of the volume of acetonitrile to the mass of the compound 1 is preferably (15-30) ml: 1g, the reaction temperature is preferably 25-35 DEG C, and the reaction time is longer than or equal to 2 hours. According to the present invention, the reaction solvent, the reaction temperature and the reaction time are optimized, and the amide condensation catalyst with the high activity is selected, such that the reaction efficiency of the compound 1 and the compound 2 is high, the lefanacin yield is significantly improved, and the high-purity lefanacin is obtained after purification.

The invention relates to the technical field of analysis and detection, and discloses a construction method of a fingerprint spectrum of relevant characteristic peaks of rhizoma coptidis paste and radix rehmanniae recen, and the construction method comprises the following steps: S1, preparing a reference solution and a test solution; and S2, injecting the reference substance solution and the test solution into a high performance liquid chromatograph, adopting a chromatographic column with octadecylsilane chemically bonded silica as a filler, taking acetonitrile as a mobile phase A, taking a 0.0125 mol / L monopotassium phosphate solution as a mobile phase B, eluting according to a specified gradient program, and detecting by adopting an ultraviolet detector to obtain the fingerprint spectrum. By means of the provided construction method of the fingerprint spectrum of the relevant characteristic peaks of the coptis chinensis paste and the radix rehmanniae recen, the sequence and the mutual relation of the characteristic peaks can be indicated, and the effect of the fingerprint spectrum of the relevant characteristic peaks of the coptis chinensis paste and the radix rehmanniae recen is effectively represented.

The invention provides a preparation method and application of an air-stable sulfide composite electrolyte, and the method comprises the following steps: S1, weighing an M source (M = Cd, Mn and Zn), P2S5 and S powder according to a ratio of 1: 1: 3, adding iodine for catalysis, carrying out heat preservation at 700-720 DEG C for 6-7 days, and carrying out K + insertion, Li + exchange and ultrasonic centrifugation to prepare a LiMyPS3 nanosheet dispersion liquid; s2, dissolving PEO and LiTFSI in acetonitrile to form a film, drying to obtain a pure PEO film, immersing the pure PEO film into a dopamine Tris buffer solution with the concentration of 2 mg / ml and the pH value of 8.5, oscillating for 12-24 hours in an oxygen environment, and washing and drying to obtain a PDA-coated PEO film; and S3, carrying out suction filtration on the LiMyPS3 dispersion liquid to obtain a self-supporting membrane, stacking according to the sequence of "PDA-coated PEO membrane-sulfide membrane-PDA-coated PEO membrane", carrying out isostatic pressing at 10-20 MPa, and then carrying out vertical cutting at 0 DEG C to obtain the 20-30 [mu] m composite membrane. The film has the advantages of good air stability, almost no loss of conductivity after 30 days, room temperature conductivity of 9.2-10.2 ms / cm, excellent interface bonding force and mechanical strength, and stable window of 4.3-4.5 V, is adaptive to a high-voltage positive electrode, and can be used for a high-energy-density solid-state lithium battery.

This present disclosure relates to the technical field of lithium-ion batteries, and particularly to a composite solid electrolyte, along with its methods of preparation and application. The preparation method comprises the following steps: mixing PEO, lithium bis(trifluoromethanesulfonyl)imide, and acetonitrile, subsequently adding the Prussian blue analogues, followed by stirring and ultrasonicating to obtain a mixed solution; the mixed solution is then formed into the composite solid electrolyte using the electrospinning technique. This present disclosure utilizes the Prussian blue analogues with a three-dimensional nanochannel structure and high specific surface area as a raw material. After preparation of the composite solid electrolyte, the pores of the composite solid electrolyte are larger and uniformly distributed, and the special pore structure establishes more stable and efficient ion transport channels, enabling smoother ion conduction and leading to enhanced electrochemical performance.

This invention discloses an analytical method for benzothiazole contaminants, comprising the following steps: detection by high performance liquid chromatography (HPLC), with the following chromatographic conditions: a phenylhexyl column as the stationary phase, mobile phase A being water, mobile phase B being acetonitrile, and gradient elution; wherein the benzothiazole contaminants are at least one of 2-aminobenzothiazole, 2-hydroxybenzothiazole, benzothiazole, 2-methylbenzothiazole, 2-mercaptobenzothiazole, 2,5-dimethylbenzothiazole, 2-cyanobenzothiazole, ethyl 2-carboxylate benzothiazole, 2-chlorobenzothiazole, 2-bromobenzothiazole, 2-methylthiobenzothiazole, phenylthiocyanate, N-tert-butyl-2-benzothiazole sulfenamide, 2-(2-hydroxyphenyl)-benzothiazole, N-cyclohexyl-2-benzothiazole sulfinamide, dibenzothiazole disulfide, and N,N-dicyclohexyl-2-benzothiazole sulfonamide.

The utility model discloses a tail gas treatment device for acetonitrile production, which comprises a tail gas absorption tower, the tail gas absorption tower comprises a first adsorption cavity, the bottom of the first adsorption cavity is provided with a first tail gas inlet pipe, the upper end in the first adsorption cavity is provided with a concentric-square-shaped bent pipe, and the lower end of the concentric-square-shaped bent pipe is uniformly provided with a plurality of nozzles; a first water blocking device and a second water blocking device which are arranged up and down are arranged in the middle of the first adsorption cavity, liquid smoothing plates which are obliquely arranged at intervals are arranged in the first water blocking device and the second water blocking device, and the inclination directions of the liquid smoothing plates of the first water blocking device and the liquid smoothing plates of the second water blocking device are opposite. The contact time of the tail gas and the absorption liquid can be prolonged, the tail gas and the absorption liquid are fully fused, and the tail gas treatment effect is improved.

The invention belongs to the technical field of pharmaceutical analysis, and particularly relates to a method for separating and determining nafamostat mesylate SM2 and related impurities thereof. The method is a high performance liquid chromatography, and comprises the following steps: by taking octadecylsilane chemically bonded silica as a chromatographic column filler, a potassium hexafluorophosphate solution as a mobile phase A and acetonitrile as a mobile phase B, separating nafamostat mesylate SM2 and related impurities thereof through linear gradient elution; and detecting by using detection wavelengths of 200 nm to 240 nm and 250 nm to 280 nm to obtain a chromatogram, so that effective determination of the nafamostat mesylate SM2 and the related impurities thereof is realized. The method provided by the invention adopts common buffer salt as a mobile phase, and has the characteristics of short analysis time, strong specificity, high sensitivity and good reproducibility.

This invention relates to a trifluoromethyl-substituted pyrene-phenylacetonitrile derivative, its preparation method, and its application. A trifluoromethyl-substituted pyrene-phenylacetonitrile derivative has the structural formula: [formula omitted]. The preparation method involves dissolving 1-pyrene formaldehyde, the corresponding trifluoromethylphenylacetonitrile, and an alkaline catalyst in an organic solvent, and carrying out a Knoevenagel condensation reaction under heating conditions. The reaction product is then post-treated to obtain the pyrene-phenylacetonitrile derivative. The application of a trifluoromethyl-substituted pyrene-phenylacetonitrile derivative in electrical storage devices is also discussed. This invention achieves precise control of storage performance by introducing trifluoromethyl groups at different positions on the benzene ring of the pyrene-phenylacetonitrile backbone, providing a novel design approach for developing new multi-level electrical storage materials. The synthesis route is concise and has broad application prospects in the field of high-density non-volatile memory.

The invention relates to a kit for quantitative detection of IGF-1 (Insulin-like Growth Factor-1) and a preparation and detection method thereof. The kit comprises a calibrator, a quality control product, an internal standard solution, an immune enrichment solution, a dissociation solution, a leacheate, an eluent, a mobile phase 1 and a mobile phase 2. The complete IGF-1 protein can be fully automatically detected from top to bottom, and the sample treatment efficiency is remarkably improved; wherein the matrix liquid used for preparing the kit adopts human serum without endogenous IGF-1, so that the in-vivo environment can be simulated to the greatest extent, and the detection deviation caused by different matrixes is reduced; an eluent of the kit adopts a formic acid-hydrochloric acid mixed acid-acetonitrile system, the system can provide a mild ionization environment through formic acid, and hydrochloric acid synergistically stabilizes the synergistic effect of the pH value of the solution, so that the ion inhibition effect is reduced, the response signal of IGF-1 is improved, and the signal-to-noise ratio of detection is further improved.

The application provides a method for inkjet printing of oligonucleotides, and belongs to the technical field of in-situ synthesis of oligonucleotides.The method comprises the following steps: modifying the surface of a solid carrier with a chemically active functional group; depositing oligonucleotide synthesis reagents onto the surface of the modified solid carrier by inkjet to perform in-situ synthesis; and the solvent in the oligonucleotide synthesis reagents comprises one or two of glutaronitrile, acetonitrile and propylene carbonate.The application uses a new type of difficult-to-vaporize solvent, greatly reduces the volatilization of reagents during inkjet synthesis and the generation of organic vapors during synthesis, and thus maintains a high in-situ synthesis reaction efficiency of oligonucleotides.