The invention relates to a chemical fiber grade polyester resin with health care function and a manufacturing method thereof, which is a high molecular polymer made from the following formula (parts by weight): dimethyl terephthalate 100, ethylene dicarboxylate Alcohol 70, negative ion powder 2-5, far-infrared powder 0-5, inorganic antibacterial powder 0-5, transesterification catalyst 0.03-0.04, polycondensation catalyst 0.03-0.04, stabilizer 0.05, its manufacturing method includes esterification reaction, function Process steps such as powder slurrying, pre-batching, decompression, polycondensation reaction, and discharging. Compared with the prior art, the product of the invention has various health care functions such as negative ions, far infrared, antibacterial, electromagnetic wave absorption, etc. The method of the invention is reasonable, and the product obtained by the method has good spinnability.