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A kind of mucous membrane protective agent for artificial insemination of livestock and its preparation method
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A mucosal protection, livestock technology, applied in medical science, surgery, etc., can solve the problems of vaginal or uterine mucosal damage, bacterial infection, and artificial insemination.
Active Publication Date: 2021-05-14
郑州乐迪生物科技有限公司
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Abstract
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Problems solved by technology
[0004] However, in the above-mentioned prior art, the lubricant for artificial insemination is gel-like, which cannot be evenly distributed on the surface of the vaginal mucosa during the insertion of the vas deferens into the vagina, which often causes damage to the vaginal mucosa or uterine mucosa, and is easy to cause the vaginal mucosa or uterus to be drawn by the female livestock. The mucous membrane is subject to mechanical damage or bacterial infection, and this lubricant does not have antibacterial effect, so it is easy to cause infection and inflammation of the vagina or uterus of female livestock
In addition, the existing lubricants can easily inactivate livestock sperm and cannot meet the needs of artificial insemination
Method used
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Examples
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Effect test
Embodiment 1
[0020] A mucosal protective agent for artificial insemination of livestock, characterized in that it comprises the following raw materials in parts by mass: 30 parts of pharmaceutical grade white oil, 30 parts of pharmaceutical grade liquid paraffin, 30 parts of pharmaceutical grade ethyl oleate; 1 part of nepeta volatile oil, 1 part of nepeta volatile oil, 1 part of zedoary volatile oil, 1 part of coriander volatile oil, 1 part of basil volatile oil, 1 part of calamus volatile oil; 10 parts of lauroyl polyoxyethylene (12) glyceride, sorbitan trioleate Pan 85) 10 parts; vitamin E 0.2 parts, ascorbyl palmitate 0.2 parts.
[0021] The preparation method of Nepeta volatile oil is as follows: decoct Nepeta nepeta in purified water with 6 times the mass for 1 hour, decoct the filtered medicinal residues with purified water with 4 times the mass of medicinal residues for 1 hour; combine two decoctions The final filtrate is filtered and concentrated to the weight of the original medi...
Embodiment 2
[0028] A mucosal protective agent for artificial insemination of livestock, characterized in that it comprises the following raw materials in parts by mass: 30 parts of pharmaceutical grade white oil, 30 parts of pharmaceutical grade liquid paraffin, 30 parts of pharmaceutical grade ethyl oleate; 1 part of nepeta volatile oil, 1 part of zedoary volatile oil, 1 part of coriander volatile oil, 1 part of basil volatile oil, 1 part of calamus volatile oil; 10 parts of soybean lecithin, 10 parts of egg yolk lecithin; 0.2 parts of butyl hydroxytoluene.
[0029] The preparation method is the same as in Example 1.
Embodiment 3
[0031] A mucosal protective agent for artificial insemination of livestock, characterized in that it comprises the following raw materials in parts by mass: 30 parts of pharmaceutical grade white oil, 30 parts of pharmaceutical grade liquid paraffin, 30 parts of pharmaceutical grade ethyl oleate; 1 part of oil, 1 part of nepeta volatile oil, 1 part of zedoary volatile oil, 1 part of coriander volatile oil, 1 part of basil volatile oil, 1 part of calamus volatile oil; 20 parts of aluminum distearate; 0.4 part of ascorbyl palmitate.
[0032] The preparation method is the same as in Example 1.
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PUM
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Abstract
The invention relates to the technical field of artificial insemination of livestock, in particular to a mucosal protective agent for artificial insemination of livestock and a preparation method thereof, comprising 90-150 parts of a base, 1-15 parts of a bacteriostatic agent, and 10-30 parts of an emulsifying thickener , 0.1-0.5 parts of antioxidant; the present invention is in a liquid state, has good lubricity, can be easily poured into the vagina and cervix of female livestock, and adheres to the vagina and cervical mucous membrane. It plays the role of lubrication, antibacterial and mucous membrane protection. The raw materials used in the present invention are pharmaceutical-grade excipients without any toxic and side effects, nor will it cause changes in the properties of artificial insemination semen, do not affect the vitality of sperm, and have a certain Antibacterial ability, to avoid damage and infection of female vaginal mucosa and cervix.
Description
technical field [0001] The invention relates to the technical field of artificial insemination of livestock, in particular to a mucosal protective agent for artificial insemination of livestock and a preparation method thereof. Background technique [0002] With the rapid development of animal husbandry, female livestock, as a key link in the breeding production process, plays a decisive role in breeding efficiency. In order to improve production efficiency, most modern intensive farms use artificial insemination for livestock breeding. During artificial insemination, it is necessary to insert the vas deferens into the vagina of the female livestock, and then inject the semen prepared in advance into the female livestock. The vas deferens are divided into multi-use and disposable. On the one hand, the sponge head of the vas deferens has a certain friction force. On the other hand, the disinfection and sterility assurance measures of the vas deferens itself are not perfect. I...
Claims
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Application Information
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