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Pharmaceutical composition for preventing and treating dry socket

A dry socket and drug technology, applied in the field of medicine, can solve the problems of easy corruption, increased infection probability, and iodoform has no obvious analgesic effect, so as to prevent entering the cavity, improve the quality of life, and improve the effect of oral infection

Inactive Publication Date: 2019-03-15
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The local iodoform gauze packing method is the most commonly used method. Under local anesthesia, 3% hydrogen peroxide cotton balls are used to wipe the tooth extraction socket for debridement, rinsed with 0.9% sodium chloride solution, and the iodoform gauze is packed into the tooth extraction wound. Take it out after 10 days, and wait for granulation The tissue grows and heals naturally. However, iodoform has no obvious analgesic effect and cannot relieve the patient's severe pain symptoms. Analgesics are needed for auxiliary treatment. Moreover, iodoform itself has a pungent taste, which is more obvious when it is placed in the mouth. In addition, iodoform is toxic to a certain extent and has potential risks when used in the oral cavity; gelatin sponges soaked in painkillers or anti-infective drugs are also used in dry baths in clinical practice. However, its main component is protein, which is easily corrupted in the environment of bacteria in the oral cavity, leading to infection, and the gelatin sponge has poor viscosity and is easy to fall off, which affects the plumpness of blood clots; metronidazole, dexamethasone, zinc oxide, etc. The drug paste made with eugenol needs to be prepared in strict accordance with the powder-liquid ratio every time, and the operation is complicated, and the frequent application of antibiotics and glucocorticoids also has certain adverse effects on the human body

Method used

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  • Pharmaceutical composition for preventing and treating dry socket
  • Pharmaceutical composition for preventing and treating dry socket
  • Pharmaceutical composition for preventing and treating dry socket

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The medicine for preventing and treating dry socket of the present embodiment, the ratio of each raw material is as follows: dog spine hair: 8.0g, clove oil: 4.0g, guaiacol: 4.0g, Peruvian balsam: 83.0g, chlorobutanol: 1.0g.

[0033] The medicine preparation method is:

[0034] 1) Take the dog spine hair, wash, dry and sieve for later use;

[0035] 2) Mix clove oil, guaiacol, peru balsam and chlorobutanol, and stir evenly at room temperature to obtain a mixed solution;

[0036] 3) Immerse the dog spine hair obtained in step 1) into the mixed solution in step 2) to make it completely infiltrated.

[0037] An embodiment of the drug is a dog spine dressing.

Embodiment 2

[0039] The medicine for preventing and treating dry socket of the present embodiment, each raw material ratio is as follows: dog spine hair is 8.25g, clove oil is 4.25g, guaiacol is 4.25g, Peru balsam is 82.0g, chlorobutanol is 1.25g.

[0040] Its preparation method is the same as that of Example 1, and the specific embodiment of the medicine is dog spine hair dressing.

Embodiment 3

[0042] The medicine of preventing and treating dry socket of the present embodiment, each component distribution ratio is as follows: dog spine hair is 8.5g, clove oil is 4.5g, guaiacol is 4.5g, Peru balsam is 81.0g, chlorobutanol is 1.5g.

[0043] Its preparation method is the same as that of Example 1, and the specific embodiment of the medicine is dog spine hair dressing.

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Abstract

The invention discloses a medicine for preventing and treating dry socket. The prepared medicine is prepared from the following raw materials in percentage by mass: 7 to 9 percent of dog ridge hairs,3 to 5 percent of clove oil, 3 to 5 percent of guaiacol, 70 to 90 percent of peru balsam and 5 to 2.0 percent of chlorobutanol, wherein the sum of mass percentages of the raw materials is 100 percent.The medicine can quickly stop bleeding, effectively relieve pain, improve oral infection and improve the life quality of patients, is safe to use and has no obvious toxic or side effects.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a medicine for preventing and treating dry socket. Background technique [0002] Dry socket is one of the more serious complications after tooth extraction, also known as alveolar osteoosteitis, localized osteomyelitis, etc. It is more common in mandibular posterior teeth, especially after extraction of impacted mandibular third molars , other teeth are rare, and the incidence rate of anterior teeth is the lowest. The main manifestation is severe pain 2 to 3 days after tooth extraction, which radiates to the ear-temporal region, submandibular region or the top of the head, which cannot be relieved by general analgesic drugs. Clinical examination shows that the alveolar socket is empty, or there are corrupted blood clots, which are grayish white. The dead matter covering the wall of the alveolar socket has an odor, and the bone surface can be directly touched with a probe and ...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K9/00A61K47/46A61P1/02A61P7/04A61P31/02A61P31/04A61K31/045A61K31/085
CPCA61K9/0024A61K31/045A61K31/085A61K36/12A61K36/48A61K36/61A61K47/46A61P1/02A61P7/04A61P31/02A61P31/04A61K2300/00
Inventor 王晓娟王济冯斌赵慧雯王莹雷丸
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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