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Yellow fluorescent graphene quantum dot, method for preparing same and application of yellow fluorescent graphene quantum dot

A graphene quantum dot and yellow fluorescence technology, applied in the field of nanomaterials, can solve problems such as nausea and adverse reactions, and achieve the effects of easy operation, low price and simple preparation method

Active Publication Date: 2019-05-10
SHANGHAI INST OF TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As an emerging drug recently developed to alleviate and treat the calcification defense of the human body, its excellent therapeutic performance and low toxicity are significantly better than the traditional treatment methods in the past, but excessive sodium thiosulfate in the human body will cause Nausea, nausea, loss of appetite, and even cause a series of adverse reactions

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  • Yellow fluorescent graphene quantum dot, method for preparing same and application of yellow fluorescent graphene quantum dot
  • Yellow fluorescent graphene quantum dot, method for preparing same and application of yellow fluorescent graphene quantum dot
  • Yellow fluorescent graphene quantum dot, method for preparing same and application of yellow fluorescent graphene quantum dot

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Embodiment 1

[0040] A preparation method for yellow fluorescent graphene quantum dots, comprising the steps of:

[0041] S1: According to the feed ratio of 0.1g: 30mL: 2mL, mix the julolidin solid, absolute ethanol liquid and acetic acid liquid, and then sonicate at room temperature for 10 minutes;

[0042] S2: Put the ultrasonicated reaction solution in a high-pressure reactor, and prepare graphene quantum dots by solvothermal method;

[0043] S3: The reaction solution is purified by dialysis, and the dialysate is concentrated and freeze-dried to obtain yellow fluorescent graphene quantum dots.

[0044] The application of the yellow fluorescent graphene quantum dot prepared by the above preparation method as a fluorescent probe in the detection of thiosulfate and hydrogen peroxide in water samples and human serum comprises the following steps:

[0045] S1: Take 1 mg of a yellow fluorescent graphene quantum dot prepared by the above preparation method at room temperature and dissolve it i...

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Abstract

The invention discloses a yellow fluorescent graphene quantum dot, a method for preparing the same and application of the yellow fluorescent graphene quantum dot. The method includes steps of S1, mixing Julolidine solid, absolute ethyl alcohol liquid and acetic acid liquid with one another according to a feed ratio of 0.1 g:30 mL:2 mL and then carrying out ultrasonic treatment under the room-temperature condition for 10 minutes; S2, placing reaction liquid in high-pressure reaction kettles after the ultrasonic treatment is carried out on the reaction liquid, and preparing graphene quantum dotsby the aid of solvothermal processes; S3, purifying reaction liquid by the aid of dialysis processes and concentrating, freezing and drying dialysate to obtain the yellow fluorescent graphene quantumdot. The yellow fluorescent graphene quantum dot, the method and the application have the advantages that the method includes simple technologies and is low in cost, the yellow fluorescent graphene quantum dot prepared by the aid of the method has uniform particle sizes, is nontoxic, can be used as a fluorescent probe to be directly applied to detecting thiosulfuric acid radicals and hydrogen peroxide in water samples and serum from human bodies and can be conveniently and quickly operated, and accurate detection results can be obtained.

Description

technical field [0001] The invention relates to the technical field of nanomaterials, in particular to a yellow fluorescent graphene quantum dot and its preparation method and application. Background technique [0002] Graphene quantum dots are a new type of fluorescent nanomaterial developed in the last ten years. In 2004, Geim et al. discovered graphene nanosheets with a single-atom thickness. Then graphene was developed and utilized by a large number of researchers. Then people discovered graphene quantum dots. , and shows excellent near-infrared optical properties, and has a wide range of applications in fluorescent acceptors, its energy resonance transfer can reach 30nm, and it shows excellent biocompatibility in a variety of cells, and because carbon is The basic constituent elements of life give it unparalleled advantages in the field of biomedicine. [0003] Sodium thiosulfate has been used to rescue cyanide drug poisoning in the past. In recent years, scholars at h...

Claims

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Application Information

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IPC IPC(8): C09K11/65C01B32/184B82Y20/00B82Y40/00G01N21/64
Inventor 徐虎翁维阳李涵洋王宇红
Owner SHANGHAI INST OF TECH
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