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Dielectric microsphere-assisted detection film and its preparation method and super-resolution detection method

An auxiliary detection and super-resolution imaging technology, which is applied in the field of micro-optical detection, can solve the problems of difficult manipulation of imaging quality, etc., and achieve the effects of insignificant loss, improved resolution, and difficult manipulation

Active Publication Date: 2020-07-28
XI AN JIAOTONG UNIV
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Problems solved by technology

[0006] In order to overcome the shortcomings of the existing microsphere super-resolution detection technology, such as difficult manipulation and poor imaging quality, a dielectric microsphere-assisted microscope super-resolution detection method based on template-induced self-assembly technology is provided, which can achieve a large field of view that is easy to adjust , far-field super-resolution detection

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  • Dielectric microsphere-assisted detection film and its preparation method and super-resolution detection method
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  • Dielectric microsphere-assisted detection film and its preparation method and super-resolution detection method

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[0040] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0041]In describing the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", " The orientations or positional relationships indicated by "vertical", "horizontal", "top", "bottom", "inner" and "outer" are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and Simplified descriptions, rather than indicating or implying that the device or element referred to must have a particular orientation, be constructed and operate in a particular orientation, and thus should not be construed as limiting the invention. In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importa...

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Abstract

The invention discloses a medium microsphere assisted detection thin film and a preparation method thereof, and a super-resolution detection method. The medium microsphere assisted detection thin filmcomprises a plurality of tightly connected chambers, each chamber is filled with a medium microsphere, the chambers and medium microspheres are encapsulated in a shell body, the uniform periodic arrangement of the microspheres is easy to realize, and the problem of the uniform periodic arrangement of the medium microspheres is solved; localized super-resolution detection of an object is realizedby changing positions of the medium microspheres; spatial morphologies of the medium microspheres are changed by extending a PDMS thin film, and the micro-manipulation of object monitoring performanceis realized; and the problem that the medium microspheres must depend on the liquid infiltration method to change the super-resolution in the microspheres and at the microsphere boundary is solved.

Description

technical field [0001] The invention belongs to the technical field of micro-optical detection, and relates to the field of micro-nano manufacturing, silicon dioxide (SiO 2 ) microspheres and polydimethylsiloxane (PDMS) films, and also involves the analysis of physical optics and geometric optics for detection methods. Specifically, it relates to a dielectric microsphere-assisted detection film based on template-induced self-assembly, a preparation method thereof, and a super-resolution detection method. Background technique [0002] In the field of nanophotonics, biochips, communication chips, sensor chips, and memory chips all have high integration and super-resolution requirements for nano-optical and photonic devices. [0003] Among the existing super-resolution techniques, there are super-resolution fluorescence microscopy, structured illumination microscopy, and surface plasmon super-resolution techniques. Super-resolution fluorescence microscopy technology uses fluo...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/01G01N21/84
Inventor 王兰兰谷同凯刘红忠
Owner XI AN JIAOTONG UNIV
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