Hypoxic cell irradiation device

Abstract

The invention discloses a hypoxic cell irradiation device. The hypoxic cell irradiation device comprises an irradiation box, an air control unit and a dosage monitoring unit, wherein the irradiation box adopts a box-shaped structure consisting of 6 irradiation box wall plates in a spiced combination manner, and an air inlet, an air outlet and a plurality of sockets are formed in the irradiation box side walls; the air control unit is connected with the irradiation box through the socket, and is used for controlling air in the irradiation box; and the dosage monitoring unit is connected with the irradiation box through the socket and is used for detecting the irradiation dosage in the irradiation box. According to the hypoxic cell irradiation device disclosed by the invention, the dosage ofdifferent positions in the irradiation box can be accurately monitored and measured, and accurate physical dosage data is provided for measurement of relative biological effects on the hypoxic cellsin different positions.

Description

technical field [0001] The present disclosure relates to the field of radioactivity detection, in particular to a hypoxic cell irradiation device. Background technique [0002] Cancer is a common and frequently-occurring disease that seriously endangers human life and health. The incidence of cancer in my country is severe, and the morbidity and mortality continue to rise. The number of new cases exceeds 4.3 million each year, and the number of deaths exceeds 2.8 million. The number one killer of national health in my country, it has become the biggest public health problem in my country (W.Chen, R.Zheng, P.D.Baade, et al. Cancer Statistics in China, 2015, CA Cancer J Clin., 2016.; 66( 2): 115-32). Radiation therapy, surgery and chemotherapy are the three conventional means of cancer treatment at present. In the current treatment of cancer patients, more than 70% of patients need different degrees of radiation therapy. [0003] Compared with γ-rays, X-rays and electron beams...

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Problems solved by technology

[0006] However, the existing technology can only maintain the stability of the oxygen partial pressure during the irradiation process, such as normoxia or a low oxygen or anoxic state with a fixed oxygen partial pressure concentration; due to the uneven physical dose of charged particles in the irradiation volume, it is necessary to Real-time tracking of the physical dose at different locations, and the need to simulate the situation at different locations inside the tumor to achieve real-time monitoring of the dose of hypoxic cells at different locations

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