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Composition and use thereof in treatment of anal fissure

A technology of composition and application, which is applied in the field of anal fissure treatment, and can solve problems such as side effects of overdose and reduction of sphincter pressure

Pending Publication Date: 2019-06-11
THD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These lead to a decrease in maximal sphincter pressure at rest, with serious overdose side effects in cardiac and diabetic patients

Method used

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  • Composition and use thereof in treatment of anal fissure
  • Composition and use thereof in treatment of anal fissure
  • Composition and use thereof in treatment of anal fissure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0097] Process for producing a composition in the form of a gel-cream according to the invention

[0098]The ingredients are introduced into the mixer according to the program and the contents provided in the recipe. The raw materials to be melted prior to mixing with the other ingredients of the formulation are melted in the melting unit at a temperature in the range of 75-80°C.

[0099] Subsequently, the temperature of the mixture was lowered to 50-55°C, and Myoxinol dissolved in hot pure water (50-55°C) was added, and then β-glucan (2% solution) and The other ingredients are added together. At a temperature below 35°C, these ingredients are added to the mixture and mixing is continued until a ready-to-use / package semi-processed product is obtained.

[0100] Preparation Example

[0101] Examples of compositions of the invention formulated as gels / creams and functionalized for said use are given in Table 1 below.

[0102] Table 1

[0103]

[0104]

[0105] Rec...

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PUM

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Abstract

The present invention relates to a composition comprising at least one protein extract of a plant of the genus Hibiscus and / or at least one beta-glucan or a salt thereof. Furthermore, the present invention relates to the use of the composition in the treatment of anal fissure.

Description

[0001] The present invention is a divisional application of Chinese patent application 201280068454.1 filed on January 30, 2012. The title of the original application is "a composition and its use in the treatment of anal fissure". field of invention [0002] The present invention relates to a composition comprising at least one protein extract of hibiscus and / or at least one beta glucan. Furthermore, the invention relates to the use of said composition for the treatment of anal fissures. Background of the invention [0003] An anal fissure is an ulceration of the epithelium of the inferior anal canal, usually at the level of the retrocanal commissure and accompanied by contracture of the internal sphincter. [0004] Tears in the anal mucosa at the site of chapping cause light bleeding, which occurs during defecation. The condition of internal sphincter contracture results in high tension of the anal canal, which is the cause of pain (the main symptom). The pain is so inte...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P17/02A61K131/00A61K38/01A61K31/716
CPCA61K31/716A61K36/185A61K9/0031A61K47/10A61K47/36A61P1/00A61P1/04A61P13/00A61P17/02A61P9/14A61K2300/00A61K9/00A61K38/011A61K38/168
Inventor F·巴斯蒂亚M·萨克曼诺
Owner THD