A body fluid pterin spectrum detection kit and its use

A kit and pterin spectrum technology are applied in chemical analysis and clinical medicine and medical fields, which can solve the problems of complex composition of pterin spectrum, difficult differential diagnosis, low sensitivity and specificity, etc.
CN109946412BActive Publication Date: 2021-10-15SHANGHAI IND TECH INST
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI IND TECH INST
Publication Date
2021-10-15

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Abstract

The invention discloses a body fluid pterin spectrum detection kit and its use. The kit includes pterin mixed standards and creatinine.
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Description

technical field

[0001] The invention relates to the field of chemical analysis and clinical medicine and medicine. In particular, it relates to a new combination marker of pterin metabolites and its application in the preparation of a kit for screening hyperphenylalaninemia subtypes. Background technique

[0002] Pterin compounds are derivatives of pteridine, which are widely distributed in blood, urine, cerebrospinal fluid and other body fluids in the human body, but the content is very small. Pterin compounds play an important auxiliary role in the process of cell metabolism. The content of pterin compounds in healthy human body fluid is low and stable. When the immune system is activated by certain diseases such as cancer (such as kidney cancer, breast cancer), the content of pterin compounds changes significantly. Hyperphenylalaninemia (HPA) is a common autosomal recessive metabolic disease that can lead to severe intellectual disability. Differences in genetic variat...

Claims

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