High sensitivity biosensor and preparation method thereof

Abstract

The invention discloses a high sensitivity biosensor and a preparation method thereof. The high sensitivity biosensor comprises the following parts of an integrated light source configured to generatean optical signal; a filtering unit comprising an annular resonance unit and configured to receive an input light source signal and generate a detection input optical signal with narrow bandwidth; asensing unit comprising an annular array and a Mach-Zehnder interferometer array and configured to receive the input optical signal and generate a sensing optical signal, wherein the wavelength and light intensity of the sensing optical signal change according to information such as the concentration of the substance to be detected; and a detecting unit configured to analyze the presence and concentration information of each substance component in the measured mixture according to the output sensing optical signal.

Description

technical field [0001] The invention relates to a high-sensitivity biosensor and a preparation method thereof, belonging to the field of optical sensors. Background technique [0002] As a new type of sensor, optical sensor is widely used in biomedicine, environmental monitoring, food safety, chemical detection and so on. [0003] At present, optical sensors based on ring resonators have been widely studied, but the sensitivity and accuracy of ring resonator optical sensors are determined by the Q value of the ring resonator, although increasing the size of the resonator and reducing the loss can increase the Q value, Improve the sensitivity of the sensor, but increasing the size of the resonator conflicts with the measurement range, and reducing the loss requires a high-tech manufacturing process, and the current ring resonator-type optical sensor is mainly based on a specific substance for sensing and measurement, and cannot measure multiple substances at the same time. T...

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Problems solved by technology

[0003] At present, optical sensors based on ring resonators have been widely studied, but the sensitivity and accuracy of ring resonator optical sensors are determined by the Q value of the ring resonator, although increasing the size of the resonator and reducing the loss can increase the Q value, Improve the sensitivity of the sensor, but increasing the size of the resonator conflicts with the measurement range, and reducing the loss requires a high-tech manufacturing process, and the current ring resonator-type optical sensor is mainly based on a specific substance for sensing and measurement, and cannot measure multiple substances at the same time. The cascaded ring resonant cavity structure is also to extract light of different resonant wavelengths or use the cascaded vernier effect to improve sensor sensitivity

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