Preparation method for supercritical extraction of effective components of antiviral oral liquid

Abstract

The invention discloses a preparation method for supercritical extraction of effective components of an antiviral oral liquid. The method comprises the steps of weighing nine herbal materials including radix isatidis, rhizoma phragmitis and the like in proportion, mixing fructus forsythiae, radix curcumae and the like for pulverizing, and conducting supercritical extraction on volatile oil and herbal residues through carbon dioxide; mixing the rest herbal materials, then performing pulverizing, extracting powdered effective components by means of a supercritical approach, and adding water andthe herbal residues for boiling into a concentrated liquid; finally, fully mixing the concentrated liquid diluted by absolute ethyl alcohol with the volatile oil coated with cyclodextrin, performing filtering at a constant volume, and conducting filling and sterilizing to prepare the antiviral oral liquid. The method adopts supercritical extraction of the nine effective components including the radix isatidis, the fructus forsythiae and the like, and has the advantages that the stability of the volatile oil can be greatly improved, the rate of extracting micromolecular antiviral effective components in the nine herbal materials is increased by 10-30% in comparison with a traditional water boiling method, macromolecular components which are poor in effect or have no effect are left in the residues obtained by supercritical extraction and do not participate in a water boiling degradation stage, and therefore the antiviral effective components are increased / enriched.

Description

technical field [0001] The invention relates to a preparation method of a Chinese patent medicine, in particular to a preparation method of supercritical extraction of active ingredients of a traditional Chinese medicine antiviral oral liquid and various modified products thereof. Background technique [0002] Antiviral oral liquid is a well-known and well-known product that has been approved by the state for many years. It is mainly used for the treatment of wind-heat cold and flu. According to the theory of traditional Chinese medicine, among the active ingredients that make up the antiviral composition of the present invention, Radix Radix is ​​cold in nature and bitter in taste, and has the functions of clearing away heat, detoxification, and cooling blood; Forsythia is clearing away heat and detoxifying, and has antibacterial and antiviral effects , can also enhance the immune function of the body; raw gypsum is sweet, pungent, and severe cold in nature, has the effects...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the deficiencies of the prior art, and provide a preparation method for supercritical extraction of active ingredients in an antiviral oral liquid, so as to solve the shortcomings of direct use of Radix Radix, Anemarrhena, Rehmannia, etc. for cooking in the prior art Such as low extraction rate of active ingredients of small molecule drugs, high temperature leads to reaction denaturation and inactivation, etc.

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