Vibrio parahaemolyticus phage VP-HYP2 and application thereof

A VP-HYP2, Vibrio hemolyticus technology, applied in the direction of bacteriophage, virus/phage, application, etc., can solve problems such as the environment that does not meet the sustainable development of fishery, pollution, drug resistance problems, etc., to reduce the number of bacteria and tolerate Wide-ranging, thermally stable effects
CN110317792AActive Publication Date: 2019-10-11TAIZHOU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
TAIZHOU UNIV
Publication Date
2019-10-11

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Abstract

The invention discloses a vibrio parahaemolyticus phage VP-HYP2 and application of the vibrio parahaemolyticus phage VP-HYP2 in prevention and control over pathogenic vibrio parahaemolyticus infectionof whiteleg shrimps, and belongs to the field of biotechnology. According to the vibrio parahaemolyticus phage VP-HYP2 and the application of the vibrio parahaemolyticus phage VP-HYP2, a double-layeragar plate method is utilized for separating a bacteriophage strain named the vibrio parahaemolyticus phage VP-HYP2 from wastewater generated from breeding of the whiteleg shrimps in Taizhou, and thepreservation number is CCTCCNO:M2019227. The provided vibrio parahaemolyticus phage VP-HYP2 is wide in pH tolerance range and high in thermostability, after the vibrio parahaemolyticus phage VP-HYP2is used for treating pathogenic vibrio parahaemolyticus causing acute hepatopancreatic necrosis of the shrimps, the number of bacteria is significantly reduced in a short time, and therefore the provided vibrio parahaemolyticus phage VP-HYP2 has a good application prospect in prevention and control over the pathogenic vibrio parahaemolyticus causing acute hepatopancreatic necrosis of the shrimps.
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Description

technical field

[0001] The invention relates to the field of biological technology, in particular to Vibrio parahaemolyticus phage VP-HYP2 and its application in preventing and treating pathogenic Vibrio parahaemolyticus infection of Penaeus vannamei. Background technique

[0002] Penaeus vannamei is one of the main aquaculture species in my country and occupies an important position in the fishery economy. In recent years, the vannamei industry is facing severe acute hepatopancreas necrosis disease (AHPND), which has caused huge economic losses to the vannamei aquaculture industry. Studies have shown that the pathogenic bacteria of acute hepatopancreatic necrosis of Penaeus vannamei is mainly Vibrio parahaemolyticus with virulence genes pirA and pirB.

[0003] Antibiotics are currently more effective drugs for the prevention and treatment of acute hepatopancreatic necrosis of prawns, but the large and frequent use of antibiotics will cause problems of drug resistance and e...

Claims

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