Peony seed shell wood vinegar liquid and preparation method and application of carrier thereof
A technology of peony seed shell and wood vinegar, which is applied in the manufacture of pyrolignoic acid, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc. Liquid damage and other problems, to achieve the effect of long release and good sustained release effect
Active Publication Date: 2019-10-22
SHANDONG ANALYSIS & TEST CENT
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Problems solved by technology
However, the inventors have found that the above-mentioned application methods have the following problems: the wood vinegar has a low antioxidant capacity, and the wood vinegar is released quickly in a short period of time, so that the wood vinegar cannot be kept in a long period of time. The effective concentration, and the direct application of wood vinegar will make the wood vinegar easy to be destroyed by the external environment
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[0039] It should be noted that the following detailed description is exemplary and intended to provide further explanation of the present invention. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
[0040]It should be noted that the terminology used here is only for describing specific embodiments, and is not intended to limit exemplary embodiments according to the present invention. For example, as used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should also be understood that when the terms "comprising" and / or "comprising" are used in this specification, their Indicates the presence of features, steps, operations, means, components and / or combinations thereof.
[0041] As mentioned above, the existing method of directly applying wood vinegar withou...
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Abstract
The invention relates to the technical field of wood vinegar preparation, and in particular relates to a preparation method and application of peony seed shell wood vinegar liquid and a carrier thereof. The method comprises the following steps: removing impurities from peony seed shells, pyrolyzing and retorting to obtain crude peony seed wood vinegar liquid, standing, taking supernatant to obtainrefined peony seed wood vinegar liquid, and freeze drying to obtain peony seed wood vinegar solid powder; mixing the wood vinegar solid powder with water to obtain a wood vinegar solution; dissolvingTween 65, Span 40 and polyethylene glycol-12-hydroxystearate in a solvent; then distilling under reduced pressure to remove the solvent to obtain a mixture film; injecting the mixture film into the wood vinegar solution to obtain the wood vinegar vesicle drug carrier. According to the invention, the peony seed wood vinegar solid powder obtained by freeze-drying treatment is encapsulated in vesicles, so that the problems of low antioxidant capacity of the wood vinegar liquid, quick release of the wood vinegar liquid in a short time and the like caused by a mode of directly applying the wood vinegar liquid without the carrier are effectively overcome.
Description
technical field [0001] The invention relates to the technical field of wood vinegar preparation, in particular to a preparation method and application of peony seed shell wood vinegar and its carrier. Background technique [0002] The information disclosed in the Background of the Invention is only intended to increase the understanding of the general background of the invention, and is not necessarily to be taken as an acknowledgment or any form of suggestion that the information constitutes the prior art that is already known to those skilled in the art. [0003] Peony is a plant belonging to Paeoniaceae and Paeoniae genus. It is a perennial deciduous shrub and has good utilization value. The flowers, roots and stems of peony can be used as medicine, and the seeds of peony can be made into oil, which has been fully utilized by people for further processing. Peony seed husk is a by-product of peony seed kernel extraction, which is hard in texture and is generally used as w...
Claims
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IPC IPC(8): C10C5/00A61K47/26A61K47/14A61K9/127A61K36/71A61K36/65A61P39/06
CPCA61K9/1272A61K9/1273A61K36/65A61K36/71A61K47/14A61K47/26A61P39/06C10C5/00Y02E50/10
Inventor 刘峰刘金鹏程冉冉王金英刘伟耿岩玲王晓
Owner SHANDONG ANALYSIS & TEST CENT