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A kind of colchicine oral solution and its prescription composition

A technology of colchicine and oral solution, which is applied in the field of colchicine oral solution and its preparation, and can solve problems such as inability to sterilize and filter

Active Publication Date: 2021-11-26
HANGZHOU BIO SINCERITY PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Another object of the present invention is to solve the problem of inability to sterilize and filter in the production process of the prior art

Method used

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  • A kind of colchicine oral solution and its prescription composition
  • A kind of colchicine oral solution and its prescription composition
  • A kind of colchicine oral solution and its prescription composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Autumn water 0.005％ Hydroxypropylmethylcellulose 2％ Hydroxyenyl ester 0.18％ Hydroxybenzyl 0.02％ Propanediol 10％ Waterless citrate 0.2％ Sodium hydrogen phosphate · twelve hydrate 1.6％ Sucralose 0.15％ Tempting red pigment 0.01％ Strawberry flavor 0.15％

Embodiment 2

[0027]

[0028]

Embodiment 3

[0030] Autumn water 0.012％ Hydroxypropylmethylcellulose 0.35％ Hydroxyenyl ester 0.18％ Hydroxybenzyl 0.02％ Propanediol 10％ Waterless citrate 0.2％ Sodium hydrogen phosphate · twelve hydrate 1.6％ Sucralose 0.15％ Tempting red pigment 0.01％ Strawberry flavor 0.15％

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PUM

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Abstract

The invention specifically relates to a colchicine oral solution and its prescription composition. It contains: colchicine, thickener, pH adjuster, bacteriostatic agent, solvent, flavoring agent, coloring agent, essence and water. The weight and volume percentages (w / v%) of each component accounting for the total volume of the solution are: 0.005% to 0.02% of colchicine, 0.1% to 2% of thickener, 0.1% to 2% of pH regulator, and bacteriostat 0.02%-0.2%, solvent 2%-10%, flavoring agent 0.1%-0.2%, pigment 0.005%-0.02%, essence 0.01%-0.2%. The colchicine oral solution provided by the invention solves the problem of sterilization and filtration in the production process under the condition of ensuring the stability of the colchicine.

Description

Technical field [0001] The present invention provides an autumn water fairy alkali oral solution and a preparation method thereof Background technique: [0002] Autumn water fairy, a biologically alkali, because it was originally extracted from Qikai Shui Xian in Qiao, the name, also known as autumn water. Pure autumn decapulsatine is yellow-shaped crystal, melting point 157 ° C. Soluble in water, ethanol and chloroform. Moon, toxic. The autumn water fairy base can inhibit mitosis, destroy the spindle, and stagnate the chromosome in the mid-range. This abnormal split caused by autumn water fairychi is called the mitosis of autumn water. In such a mitosis, although the chromosomes have fallen, the cells are not divided, and two sub-cells cannot be formed, and the chromosome is doubled. Since 1937 American scholarkslee, the number of staining numbers and other plants such as autumn water fairy, autumn, the autumn, the alkali is widely used in cytology, genetics research and plant b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K47/38A61K47/14A61K31/165A61P29/00A61P19/02A61P19/06
CPCA61K9/0095A61K31/165A61K47/14A61K47/38A61P19/02A61P19/06A61P29/00
Inventor 楼金芳金勇彪降雪周娜
Owner HANGZHOU BIO SINCERITY PHARMA TECH CO LTD