Anti-inflammatory and antibacterial pharmaceutical composition as well as preparation method and application thereof

An anti-inflammatory and antibacterial and composition technology, applied in the field of traditional Chinese medicine preparations, can solve the problems of weak anti-inflammatory effect, gastrointestinal reactions, aggravating the decline of the patient's physique, etc. Effect

Inactive Publication Date: 2020-01-10
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Non-steroidal drugs mainly include: aspirin, acetaminophen, diclofenac, indomethacin (indomethacin), ibuprofen, etc. Non-steroidal anti-inflammatory effects are weak, and there are gastrointestinal reactions, liver toxicity, Nervous system toxicity, risk of cardiovascular disease and other side effects; steroidal anti-inflammatory drugs are glucocorticoids, and general hormone drugs have strong anti-inflammatory effects, but there are side effects such as osteoporosis, infection spread, central obesity, water and sodium retention
Although the two are widely used clinically, they have strong side effects. Long-term and repeated use of anti-inflammatory drugs can also negatively affect the immune function of the body, aggravate the decline in the patient's physical fitness due to the protracted course of the disease, and cause a vicious cycle of the disease.

Method used

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  • Anti-inflammatory and antibacterial pharmaceutical composition as well as preparation method and application thereof
  • Anti-inflammatory and antibacterial pharmaceutical composition as well as preparation method and application thereof
  • Anti-inflammatory and antibacterial pharmaceutical composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0039] This example provides an anti-inflammatory and antibacterial pharmaceutical composition, the medicinal ingredients of which include the following raw material extracts in parts by weight: 160 parts of pomegranate peel, 140 parts of Scutellaria baicalensis, 120 parts of Burnet ulca, and 120 parts of Cortex Phellodendri.

[0040] The preparation method of this anti-inflammatory antibacterial pharmaceutical composition, comprises the steps:

[0041](1) Take the pomegranate peel and crush it into a coarse powder, measure the pomegranate peel coarse powder according to the above prescription, add 60% ethanol of 6 times the amount of the pomegranate peel coarse powder for the first time, heat and reflux for 15 minutes, filter to obtain the filtrate, and add the filter residue Pomegranate peel coarse powder was extracted with 60% ethanol of 4 times the amount for 10 minutes, filtered to obtain a filtrate, and the two filtrates were combined for later use.

[0042] (2) Take by ...

Embodiment 2

[0046] This example provides an anti-inflammatory and antibacterial pharmaceutical composition, the medicinal ingredients of which include the following raw material extracts in parts by weight: 130 parts of pomegranate peel, 120 parts of Scutellaria baicalensis, 100 parts of Burnet ulca, and 100 parts of Cortex Phellodendri.

[0047] The preparation method of the anti-inflammatory and antibacterial pharmaceutical composition of this embodiment is the same as that of Example 1.

Embodiment 3

[0049] This example provides an anti-inflammatory and antibacterial pharmaceutical composition, the active ingredients of which include the following raw material extracts in parts by weight: 140 parts of pomegranate peel, 130 parts of Scutellaria baicalensis, 110 parts of Burnet ulca, and 110 parts of Cortex Phellodendri.

[0050] The preparation method of the anti-inflammatory and antibacterial pharmaceutical composition of this embodiment is the same as that of Example 1.

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Abstract

The invention provides an anti-inflammatory and antibacterial pharmaceutical composition. The pharmaceutical composition comprises the following active ingredients in parts by weight: 130-190 parts ofpomegranate rind, 120-160 parts of scutellaria baicalensis, 100-140 parts of sanguisorba officinalis and 100-140 parts of phellodendron amurense. In addition, the invention also provides a preparation method of the anti-inflammatory and antibacterial pharmaceutical composition. The anti-inflammatory and antibacterial pharmaceutical composition is a pure traditional Chinese medicine preparation, has good anti-inflammatory and antibacterial effects, is small in dosage, convenient to take, wide in application range, definite in curative effect, safe and reliable, free of relapse in curing, freeof drug property dependence and free of side effects, and can achieve the effect of treating both symptoms and root causes.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to an anti-inflammatory and antibacterial pharmaceutical composition and a preparation method and application thereof. Background technique [0002] Inflammation is a common and multiple disease. It is a preventive reaction of living tissue to inflammatory factors. Vascular reaction is the main link in the inflammatory process. The clinical manifestations are redness, swelling, heat, pain and dysfunction, accompanied by Systemic reactions such as fever, leukocytosis, and mononuclear-phagocyte system hyperplasia are a process mediated by inflammatory mediator molecules or cytokines. Most of the inflammatory mediator molecules are derivatives of arachidonic acid, mainly including prostaglandins (PGs), leukotrienes (LTs), thromboxane (thromboxane) and so on. Any factor that can cause tissue damage may cause inflammation, that is, inflammat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P1/00A61P11/00A61P13/02A61P29/00A61P31/04
CPCA61K36/185A61K36/539A61K36/739A61K36/756A61K2236/333A61K2236/39A61P1/00A61P11/00A61P13/02A61P29/00A61P31/04A61K2300/00
Inventor 向梅先苏汉文甘大莉师军凤
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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