Flexible recording electrode and preparation method and implantation method thereof

Abstract

The invention provides a flexible recording electrode. The flexible recording electrode comprises an adapter, a plurality of pin headers, and a plurality of electrode wires, the plurality of pin headers are arranged on the adapter at intervals, one ends of the plurality of electrode wires are in corresponding connection with the plurality of pin headers, one ends, away from the plurality of pin headers, of the plurality of electrode wires are bonded by a tissue glue, and a portion, not covered with the tissue glue, of the electrode wires is covered with a protective glue. The flexible recording electrode has a small volume, so that the electrical activity of a target brain area with a small area can be recorded, and the load on the animal's head can be reduced. The flexible recording electrode has good flexibility, the wound electrode wires are fixed by the tissue glue, the tissue glue can be degraded in the brain tissue, the electrode wires recover the flexibility, and can follow themovement of the brain tissue, and thereby the damage to the brain tissue is reduced. The structure is simple, and the cost is low. The invention also provides a preparation method and an implantationmethod of the flexible recording electrode.

Description

technical field [0001] The invention belongs to the technical field of recording electrodes, and in particular relates to a flexible recording electrode, a preparation method and an implantation method thereof. Background technique [0002] In the nervous system, a large number of neurons continuously generate and transmit electrophysiological signals to achieve information exchange between different brain regions and neurons. Electrophysiological technology has become a very important tool for us to study neuron activity and then neural circuit function due to its high temporal and spatial resolution recording advantages. In the past few decades, the development of recording electrodes has achieved a series of major breakthroughs, which have directly had a profound impact on neuroscience research, and quickly led to the development of four-electrode devices that can better distinguish neuron types. The development of various new electrode arrays such as Michigan microelect...

AI Technical Summary

Problems solved by technology

[0004] However, most of the commonly used metal electrodes are relatively hard, and their Young's modulus is very different from that of brain tissue, which is easy to cause mechanical damage to...

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