92 results about "Severe complication" patented technology

The present invention involves new interventional methods and devices for reconfiguring a portion of the gastrointestinal tract. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged, approximated and fastened to create one or more tissue folds forming one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications.

The present invention involves new interventional methods and devices for reducing gastric volume, and thereby treating obesity. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged and approximated to create one or more tissue folds that are then secured by placing one or more tissue fasteners to produce one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications. Minimally invasive devices for approximating and fastening soft tissues are disclosed that enable these new interventional methods to be carried out safely, efficiently and quickly. Methods for reversing the procedure are also disclosed.

The present invention involves new interventional methods and devices for reducing gastric volume, and thereby treating obesity. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged and approximated to create one or more tissue folds that are then secured to produce one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications. Methods for reversing the procedure are also disclosed.

The invention provides mesenchymal stem cell injection, as well as a preparation method and application in preparing a medicament for treating children dilated cardiomyopathy. The mesenchymal stem cell injection comprises 2*10<5>-1*10<7> mesenchymal stem cells in every milliliter, clinical grade DMSO (dimethylsulfoxide) with volume ratio of 5 to 8 percent, human albumin with mass volume ratio of 1 to 6 percent, and multi-electrolyte liquid. The mesenchymal stem cell injection is prepared from placenta and umbilical cord, has the advantages of being high in yield, and being easy to realize industrialization, the preparation system quality is easy to control; the injection can be directly frozen through program-controlled freezing procedure and directly used in clinical injection after being recovered, and is safe and reliable. According to the injection, the dilated cardial structure can be changed, the function of heart can be recovered, the water supply state of each tissue in the whole body can be improved, the living quality of a patient can be improved, and the dilated cardiomyopathy can be treated fundamentally, so that the patient can get rid of serious complications caused by massive medicine administration, living action limitation and poor disease control.

The invention relates to the technical field of medical plastic surgery, in particular to the technical field of facial filling and anti-wrinkle, in particular, it is an injection filling cosmetic modification anti-aging, skin beautification and facial rejuvenation material. The preparation formula of the present invention includes hyaluronic acid, collagen, vitamin E and PLGA. The preparation method comprises: 1) preparing high-viscosity gel; 2) preparing PLGA nano-microspheres; 3) fully mixing high-viscosity gel and PLGA nano-microspheres; 4) sterilizing and filling. Compared with the prior art, the present invention has the beneficial effect that: the combined use of collagen and hyaluronic acid reduces skin erythema, swelling, hardening or itching, muscle pain, urticaria or Other symptoms such as rash. It reduces the probability of severe complications such as peripheral blood circulation embolism, skin necrosis, retinal artery embolism, and cardiocerebral artery embolism that may be caused by simple hyaluronic acid injection, and the safety of product use is improved.

The present invention involves new interventional methods for reducing gastric volume, and thereby treating obesity. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged, approximated and fastened to create one or more tissue folds forming one or more plications projecting into the gastrointestinal space. The serosal tissue may optionally be treated during the procedure to promote the formation of a strong serosa-to-serosa bond that ensures the long-term stability of the tissue plication. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications.

The invention discloses a disposable thrombus filter connector. The disposable thrombus filter connector comprises a first connector body, a rotary piston and a second connector body which are communicated. The rotary piston comprises a sliding groove, a piston piece, a handle and a hollow cylindrical outer shell, wherein the sliding groove is formed in the lateral surface of the outer shell, the piston piece is arranged in the outer shell, the handle is arranged outside the outer shell, the piston piece and the handle are connected, and the handle drives the piston piece to rotate through the sliding groove. The disposable thrombus filter connector prevents formed thrombus from falling into blood and causing serious complications, is convenient and practical, avoids the waste of extracted blood of a patient in operation (usually 5-10 ml of the blood of the patient is abandoned due to the worries of micro thrombus), then pulse type tube flushing is carried out to guarantee the smoothness of a retain tube, and the maintenance time is longer.

The invention discloses an artificial cornea which is composed of an optical portion and a supporting portion. The optical portion and the supporting portion are integrally formed through three-dimensional printing, the optical portion is arranged in the center of the artificial cornea, the supporting portion is arranged at the periphery of the optical portion and of a net-shaped multi-hole structure, and accordingly the biological synthesis between the artificial cornea and a receptor tissue is improved. An artificial cornea in the prior art uses a lens column-supporting two-piece mode, an optical portion and a supporting portion of the artificial cornea in the prior art are separated, and aqueous fluid leakage and serous complication like endoophthalmitis are prone to happening after operation to cause transplantation failure. The integrated artificial cornea is manufactured through a three-dimensional printing technique. By means of an integrated structure, the whole artificial cornea is firm and stable in structure, not prone to deforming and capable of solving the problems caused by the two-piece artificial cornea. Individual data models can be manufactured according to parameters of an eyeball in different age groups or CT and UBM three-dimensional scanning parameters of a patient, so that individual artificial cornea can be manufactured.

The invention discloses a method for achieving surgical safety check and operation surgical risk evaluation information management on a PDA, which comprises the following steps: a, establishing a PDA special data file of important information in a surgical safety checklist and a surgical risk evaluation table; b, storing the data file into the PDA to obtain PDA storage application information; c, selecting the surgical safety checklist recommended by the WHO or the surgical safety checklist in an evaluation guide for hospital managements required by the Ministry of Health on a PDA screen, and making a choice on items of the selected surgical safety checklist one by one; d, selecting the surgical risk evaluation table on the PDA screen, and making a choice on the items of the selected surgical risk evaluation table one by one; and e, generating a surgical safety checklist with each sub item conclusion and a surgical risk evaluation table with an evaluation mark result by the PDA. The method has the advantages of effectively reducing physician-patient disputes, greatly reducing the operative mortality, and greatly reducing serious surgical complications.

Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHR) are significant global public health problems and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates, which are under clinical evaluation, induce primarily an antibody response to the virus and minimal cross-reactive T cell responses. Currently, there are no available tools to assess protective T cell responses during infection or post vaccination. The present invention incorporates immunoproteomics to uncover novel HLA-A2 specific epitopes derived from Dengue Virus (DV)-infected cells. These epitopes are conserved with epitope-specific CTLs cross-reacting against all four DV serotypes. These epitopes have potential as new informational and diagnostic tools to characterize T cell immunity in Dengue virus (DV) infection, and serves as a universal vaccine candidate complementary to current vaccines.

New interventional methods and devices for reducing gastric volume, and thereby treating obesity, are disclosed. The procedures are generally performed laparoscopically and may generally be described as laparoscopic plication gastroplasty (LPG) in which, after obtaining abdominal access, spaced apart sites on a gastric wall are engaged and approximated to create one or more tissue folds that are then secured by placing one or more tissue fasteners to produce one or more plications projecting into the gastrointestinal space. These procedures are preferably carried out entirely extragastrically (i.e. without penetrating through the gastrointestinal wall), thereby minimizing the risks of serious complications. Minimally invasive devices for engaging, approximating and fastening soft tissues are disclosed that enable these new interventional methods to be carried out safely, efficiently and quickly.

The invention discloses an artificial vertebral plate used after spine laminectomy. The artificial vertebral plate consists of a vertebral plate, a first screw and a second screw, wherein a first long round hole and a second round hole are formed in two ends of the vertebral plate, the first screw is arranged in the first long round hole, and the second screw is arranged in the second long round hole. The vertebral plate is firstly placed above the spine to be positioned, two threaded holes are drilled in sections where the vertebral plate is to be reconstructed through vertebral pedicle screws on two sides, the vertebral plate is mounted, the first screw and the second screw are tightened, mounting is finished, the vertebral plate is located above the spine, so that closed muscle and other soft tissue can be stopped during cut closure, spinal cords are protected from compression, and severe complications such as neural symptoms, paralysis and the like after the laminectomy can be avoided. The artificial vertebral plate is simple in structure, convenient to use, firm in fixation, convenient to dismount and capable of stopping closed muscle and other soft tissue during cut closure, the spinal cords are protected from compression and adhesion, the severe complications such as neural symptoms, paralysis and the like after the laminectomy can be avoided, and the artificial vertebral plate can be implanted in a patient to be used for a long term.

The invention discloses a nerve protection guide plate for mandible osteotomy. The guide plate is integrally attached to the bone face of the mandible, an arc guide area is arranged on the edge of the guide plate, and the arc and the length of the guide area are matched with the arc and the length of the inferior alveolar nerve canal. The nerve protection guide plate for mandible osteotomy enables osteotomy to be carried out more easily, and is convenient for an operator to operate; osteotomy under guidance of the guide plate allows a mandible diseased region to be cut off precisely along the boundary, residual is avoided, and the risk of postoperative recurrence is effective reduced; osteotomy under guidance of the guide plate can effectively preserve the inferior alveolar neurovascular bundle, the serious complications, such as postoperative affected side chin lip skin numbness, tooth remaining on the affected side lower jaw, nerve loss of alveolar bone and the like, ischemia, inactivation and even necrosis, due to cutting or accidentally injure are avoided, and the postoperative life quality of patients is improved.

The invention relates to a drainage tube capable of testing leakage of digestive juice. Acid test paper, litmus paper and bilirubin test paper are pasted on the inner wall of the rubber drainage tube along the direction of the drainage tube, and corresponding characters are used for respectively marking the outer walls of the rubber drainage tube which are respectively mapped by the acid test paper, the litmus paper and the bilirubin test paper. The drainage tube overcomes the defects that intestine leakage, pancreas leakage and stomach leakage can not be found promptly and a doctor suspects the occurrence of leakage of digestive juice according to clinical symptoms only, thereby avoiding misdiagnosis or missed diagnosis, preventing delayed state of an illness or severe complications, finding the situations of leakage of digestive juice such as intestine leakage, pancreas leakage and stomach leakage promptly, and facilitating prompt and effective diagnosis and treatment for clinical treatment.

The invention discloses a degradable woven occluder. The degradable woven occluder comprises a silk woven mesh, a far end and a near end, wherein the far end and the near end are arranged at both ends of the silk woven mesh; a connecting structure is arranged inside the silk woven mesh, the upper end of the connecting structure is connected with the far end, and the lower end of the connecting structure is connected with the near end or the silk woven mesh around the near end. The degradable woven occluder is completely degradable, thereby being high in long-term effects on patients and avoiding occluder complications induced by other long-term diseases; coupe pipes are hooks together in a separated mode, so that the degradable woven occluder can maintain an I-shaped form and can be good in adhesion to defects and further ensure stability and occlusion properties; an auxiliary wire can achieve protecting effects and can recover the degradable woven occluder when the degradable woven occluder falls off to avoid severe complications.

The invention relates to the field of medical cell therapy, in particular to a device and a method for rapidly and immediately separating epidermal cells, melanophore and fibroblast of human skin. The separating device comprises a micro magnetic heating stirrer, an operating panel, digestive enzyme and an isotonic electrolyte solution. According to the separating method, instruments required for cell separation of the human skin are remarkably reduced, the operation steps are simplified, time required for cell separation is remarkably shortened, application of serum is avoided, occurrence of serious complication such as allergy, pathogenic microorganism propagation and the like is remarkably reduced, and wide popularization of human skin cell transplantation application is facilitated. According to the device and the method, separated cells can be used for scar plastic surgery, treatment of abnormal pigment change such as vitiligo and scar hypopigmentation caused by various reasons and acute and chronic wound repair.

The invention belongs to the technical field of medical instruments of the orthopedics department, and discloses a multifunctional bed permeable to X-rays and capable of adjusting all joints. The bed is used for performing X-ray examination and treatment while allowing all the joints of a patient to be rotated. The bed is designed according to the range of motion of the joints of the human body, all parts of a bed board can rotate, the rotating angle is suitable for the joints of the human body, the limbs of the patient can be moved, rotated and fixed without moving the patient so that examination and treatment can be performed, fracture redislocation and corresponding serious complications such as blood vessel and nerve injury, spinal cord injury, important organ injury, lower extremity deep venous thrombosis shedding and pulmonary embolism caused when the patient is moved are prevented, the frequency of carrying the patient during hospitalization is reduced, pain of the patient is relieved, and human resources are saved. The bed is an innovation for fracture exanimation and treatment, overcomes use limitations of a traditional bed, solves problems existing for a long time, greatly shortens examination and operation time and recovery time for the patient and has great social benefits and economic benefits.

The invention discloses an application of statin medicines in preparing medicines used for treating chronic subdural hematoma (CSDH). The application provided by the invention has the advantages that: 1, the safety is high; the medicine does not cause severe complications; CSDH reoccurrence is prevented for a long time after applciation; and an effect is reliable; 2, medication is convenient and is easy to be accepted by patients, wherein the medicine needs to be taken only once a day, and an amount is appropriate, such that patient daily lives are not affected; 3, the medicine is economical, wherein the medicine can be orally taken at home, such that hospitalization costs, surgical treatment costs, and care worker costs before and after surgery are avoided; and 4, defects such as anesthesia risk, pain risk, surgical bleeding, brain physiological cycle disruption, brain function damage, postoperative infection and recurrence, and the like of a traditional borehole drainage operation used for treating CSDH are avoided.

The invention discloses a folding suspension type brain cotton pad supporting frame for neurosurgery, and belongs to a medical auxiliary instrument. The supporting frame consists of a rotating shaft 1, a panel 2, protruding teeth 3, vertical grooves 4, circular holes 5, horizontal grooves 6, a supporting rod 7 and a clamping opening 8, wherein the brain cotton pad supporting frame is made of a stainless steel material, is flexible and convenient to use and is used for holding liquid such as blood, tissue fluid and washing liquid, so contamination of a desktop of an instrument by wetted brain cotton pads and even serious complications such as intracranial infection are avoided; the supporting frame meets the requirement on the neurosurgery, can be used for storing a large number of brain cotton pads, is easy to clean after being used, can be folded into a box to reduce the space occupation and is placed in a neurosurgery instrument set to be subjected to high-pressure steam sterilization for recycling.

The invention discloses a mandibular reconstruction scaffold. The mandibular reconstruction scaffold has an irregular structure and comprises a first cross section and a second cross section, whereinan oblique angle between the first cross section and the second cross section is 30 to 60 degrees; two sides of the first cross section are respectively provided with at least one first nail hole; each first nail hole penetrates through the first cross section and the second cross section and is used for fixing the mandibular reconstruction scaffold onto a first target; and at least one second nail hole is arranged on the first cross section and used for fixing the mandibular reconstruction scaffold onto a second target. The mandibular reconstruction scaffold provided by the invention can reconstruct a mandible in a manner of compound vascularized bone graft, and can effectively reduce occurrence of serious complications like infection, rejection and stress shielding caused by mandibular reconstruction with completely-heterogeneous materials.

The invention discloses a multifunctional stomach tube with an expansion balloon. The multifunctional stomach tube comprises a stomach tube body and the expansion balloon. The stomach tube body is a hollow hose. The far end of the stomach tube body is an open circular hole. The sidewall of the far end of the stomach tube body is provided with side holes. The expansion balloon is arranged on the section, adjacent to the upper portion of the far end, of the stomach tube body. The expansion balloon is integrally in a cylinder shape. The two ends of the expansion balloon are thick, and the middle of the expansion balloon is slightly thin and is in a kidney shape. The stomach tube body is further provided with an emptying balloon. The emptying balloon is communicated with the expansion balloon through an inflation tube. The near end of the stomach tube body is provided with a sealing cap. The stomach tube body is further internally provided with a traction guide wire. The near end of the traction guide wire is provided with a handle. The multifunctional stomach tube with the expansion balloon has the advantages that the safety of an esophageal operation and a cardiac operation is improved, severe complications after the esophageal operation and the cardiac operation can be reduced, the esophagus-stomach anastomotic fistula can be more effectively treated, and therefore postoperative pain of patients can be relieved.

The invention provides a vena cava filter which comprises a columnar net barrel. Shape memory wire threads are woven to form the columnar net barrel, a filter structure which is use for filtering thrombi is arranged in the net barrel and comprises a plurality of rod-shaped filter components, one end of each filter component is connected with the inner wall of the net barrel, and the other end of each filter component is connected with a connector. The filter components are perpendicular to the axis of the net barrel and are pressure springs. The vena cava filter has the advantages that the vena cava filter is of a net barrel structure, nickel-titanium alloy wires are woven to form the net barrel, accordingly, the vena cava filter is excellent in blood vessel adherence, and severe complications due to the fact that the vena cava filter moves and falls off to the hearts and the lungs of human bodies and is broken, vena cava is perforated and the like can be prevented; the vena cava filter can be recycled and can be conveniently implanted into the human bodies and taken out of the human bodies via the connectors; the vena cava filter which is of the net barrel structure can deform, is adaptive to the shapes of the blood vessels of the human bodies, and can be contracted when implanted into the human bodies and taken out of the human bodies, so that the vena cava filter with a small diameter can be arranged in a conveyor device.

The invention discloses an endoscope surgery monitoring device, which mainly comprises an endoscope, cleaning solution for cleaning a surgical part, a pipe for injecting the cleaning solution, and a collecting container for collecting mixed liquid flowing out during the surgery, wherein the pipe is provided with a flow meter for detecting the flow of the cleaning solution, and the collecting container is internally provided with a blood concentration detector and is arranged on a weighting instrument. According to the invention, trough monitoring the bleeding amount and cleaning solution absorption amount of a patient during the surgery in real time, serious complication of water intoxication, caused by the endoscope surgery, can be effectively prevented, and the safety of the surgery is improved.

The invention innovatively adopts a flexible airbag anal and rectal dilation catheter. The risk of damage to the intestinal canal during the using process of the flexible airbag anal and rectal dilation catheter is reduced, and serious complications are avoided. Because the current hard anal dilator strongly passes through the anastomotic stenosis position, causing pain and extreme discomfort; a patient is extremely uncooperative, crying and uneasy, and affecting the dilation effect; a flexible airbag anal and rectal dilator is smooth and comfortable and greatly reduces the pain and the discomfort of the patient, the patient is highly cooperative, and the anal dilation effect is good. If the hard anal dilator is adopted, the strong dilation has the risk of anastomotic rupture when the wound is not healed in the early postoperative period, the dilation can be performed generally 2-3 weeks after the surgery, the anastomotic local scar is formed at the moment, and the dilation is difficult. The flexible airbag anal and rectal dilator is soft, the dilation strength can be controlled and adjusted, the dilation can be performed in the early postoperative period to avoid scar formation, and the dilation effect is better.

Influenza virus infection and the resulting complications are a significant global public health problem and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Improving humoral immunity to influenza is the target of current conventional influenza vaccines, however, these are generally not cross-protective. On the contrary, cell-mediated immunity generated by primary influenza infection provides substantial protection against serologically distinct viruses due to recognition of cross-reactive T cell epitopes, often from internal viral proteins conserved between viral subtypes. Efforts are underway to develop a universal flu vaccine that would stimulate both the humoral and cellular immune responses leading to long-lived memory. Such a universal vaccine should target conserved influenza virus antibody and T cell epitopes that do not vary from strain to strain. The present invention incorporates immunoproteomics to uncover novel MHC class I specific epitopes derived from influenza-infected cells. These epitopes are conserved with epitope-specific CTLs cross-reacting against various different influenza strains. These epitopes have potential as new informational and diagnostic tools to characterize T cell immunity in influenza infection, and serves as a universal vaccine candidate complementary to current vaccines.

The invention provides a vaccinium bracteatum thunb extract and an application thereof. Diabetic retinopathy is one of the serious complications of diabetes, which is an ocular fundus lesion with specific change as well as the most important expression of microangiopathy caused by diabetes. The vaccinium bracteatum thunb extract provided by the invention is prepared by the following steps: heating and extracting vaccinium bracteatum thunb with ethanol of certain concentration; concentrating the extract and adsorbing with a macroporous adsorption resin column; washing with water for removing impurities; eluting with a high-concentration ethanol solution; and concentrating the eluent and drying to obtain the vaccinium bracteatum thunb extract. The pharmacodynamics study indicates that the vaccinium bracteatum thunb extract provided by the invention can be used for preparing a medicine or food for preventing and treating diabetic retinopathy and realizes a remarkable prevention or treatment effect. The invention provides a new way of searching for a new medicine for treating diabetic complications.

The invention provides a water jet arthroscope. The water jet arthroscope comprises a pump body assembly, a water jet assembly, an endoscope module and a cryoablation assembly. The water jet assemblyis connected to the pump body assembly, the endoscope module is connected to the water jet assembly, and the cryoablation assembly includes a cryo-switch ball valve, a cryoablation catheter and a cryo-balloon. The cryo-switch ball valve is disposed on the water jet assembly, one end of the cryoablation catheter is connected to the outlet of the cryo-switch ball valve, the other end of the cryoablation catheter penetrates through the endoscope module, and the cryo-balloon is arranged at the other end of the cryoablation catheter. The water jet arthroscope is convenient to operate by a doctor, causes less bleeding, makes a patient recovery quickly after an operation, shortens the operation time, has high treatment effectiveness, reduces severe complications such as thrombosis, and lowers thepain level of a patient; besides, the doctor and an observer can view the patient's knee image in real time through an external workstation and can examine the patient's knee joint in detail, so thatthe safety of the operation is increased.