A kind of traditional Chinese medicine composition for treating gout and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating gout and a preparation method thereof, belonging to the field of traditional Chinese medicines; the raw materials of the traditional Chinese medicine composition for gout are 40-80 parts by weight of Cyclocarya paliurus, 10-40 parts of corn silk, 5‑30 parts of kudzu root, 5‑30 parts of imperina root. The raw materials of the composition are mixed according to a certain ratio, decocted, concentrated, dried, crushed and sieved, and finally packaged. The anti-gout traditional Chinese medicine composition provided by the invention has a simple formula, a simple and convenient preparation process, and can better retain the active ingredients of the composition. The curative effect of this formula in treating gout is better than that of the single traditional Chinese medicine, any combination of two traditional Chinese medicines, and the combination of three traditional Chinese medicines. Symptoms, slow down the onset of complications in patients with chronic gout, and at the same time have the characteristics of convenience, safety and no side effects.

Description

technical field

[0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating gout and a preparation method thereof. Background technique

[0002] Gout is caused by the precipitation of sodium urate crystals due to high uric acid (serum uric acid concentration > 420umol / L), which deposits in the joints and cartilage tissue around the joints, causing neutrophils and joint synoviocytes to gather at the site of sodium urate crystals and release inflammatory cells Severe inflammatory response caused by cytokines (IL-1β, TNF-α) and chemokines. [Miguel A. Martillo, Lama Nazzal, Daria B. Cfittenden The crystallization of monosodium urate. Current Rheumatology Reports, 2014, 16(2): 400].

[0003] High uric acid is the biochemical basis of gout. Increased uric acid content due to excessive production of uric acid in the body or decreased excretion of uric acid. Among them, about 90% of hyperur...

Examples

Embodiment 1

[0027] A traditional Chinese medicine composition for treating gout comprises 40 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata and 5 parts of Imperata rhizome in parts by weight.

[0028] The specific implementation steps are as follows:

[0029] a) Weigh 40 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata root and 5 parts of Imperata rhizome and place them in an extraction tank, add distilled water 8 times the total mass of raw materials into the extraction tank, so that the distilled water is fully immersed in the raw material mixture.

[0030] b) Decocting at 80° C.-100° C. for 3 times, each time for 1-2 hours, filtering each filtrate while hot, and combining the filtrates of 3 times.

[0031] c) The combined filtrate is concentrated under reduced pressure at 60° C. to a thick extract with a relative density of 1.20-1.30.

[0032] d) Dry the thick extract in a vacuum oven at 60°C to obtain a dry powder.

[0...

Embodiment 2

[0035] A composition of traditional Chinese medicine for treating gout comprises 60 parts of Cyclocarya paliurus, 25 parts of corn silk, 15 parts of kudzu root and 15 parts of Imperata rhizome in parts by weight.

[0036] The specific implementation steps are as follows:

[0037] a) Weigh 60 parts of Cyclocarya paliurus, 25 parts of corn silk, 15 parts of Pueraria lobata and 15 parts of Imperatae imperatae into an extraction tank, add distilled water 9 times the total mass of raw materials into the extraction tank, so that the distilled water fully immerses the raw material mixture.

[0038] b) Decocting at 80° C.-100° C. for 3 times, each time for 1-2 hours, filtering each filtrate while hot, and combining the filtrates of 3 times.

[0039] c) The combined filtrate is concentrated under reduced pressure at 60° C. to a thick extract with a relative density of 1.20-1.30.

[0040] d) Dry the thick extract in a vacuum oven at 60°C to obtain a dry powder.

[0041] e) Pack the dr...

Embodiment 3

[0043] A traditional Chinese medicine composition for treating gout comprises 80 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata root and 5 parts of Imperata rhizome in parts by weight.

[0044] The specific implementation steps are as follows:

[0045] a) Weigh 80 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata and 5 parts of Imperata prana in an extraction tank, add distilled water 10 times the total mass of raw materials into the extraction tank, so that the distilled water fully immerses the raw material mixture.

[0046] b) Decocting at 80° C.-100° C. for 3 times, each time for 1-2 hours, filtering each filtrate while hot, and combining the filtrates of 3 times.

[0047] c) The combined filtrate is concentrated under reduced pressure at 60° C. to a thick extract with a relative density of 1.20-1.30.

[0048] d) Dry the thick extract in a vacuum oven at 60°C to obtain a dry powder.

[0049] e) Pack the dry p...

technical field

[0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating gout and a preparation method thereof. Background technique

[0002] Gout is caused by the precipitation of sodium urate crystals due to high uric acid (serum uric acid concentration > 420umol / L), which deposits in the joints and cartilage tissue around the joints, causing neutrophils and joint synoviocytes to gather at the site of sodium urate crystals and release inflammatory cells Severe inflammatory response caused by cytokines (IL-1β, TNF-α) and chemokines. [Miguel A. Martillo, Lama Nazzal, Daria B. Cfittenden The crystallization of monosodium urate. Current Rheumatology Reports, 2014, 16(2): 400].

[0003] High uric acid is the biochemical basis of gout. Increased uric acid content due to excessive production of uric acid in the body or decreased excretion of uric acid. Among them, about 90% of hyperur...

Examples

Embodiment 1

[0027] A traditional Chinese medicine composition for treating gout comprises 40 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata and 5 parts of Imperata rhizome in parts by weight.

[0028] The specific implementation steps are as follows:

[0029] a) Weigh 40 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata root and 5 parts of Imperata rhizome and place them in an extraction tank, add distilled water 8 times the total mass of raw materials into the extraction tank, so that the distilled water is fully immersed in the raw material mixture.

[0030] b) Decocting at 80° C.-100° C. for 3 times, each time for 1-2 hours, filtering each filtrate while hot, and combining the filtrates of 3 times.

[0031] c) The combined filtrate is concentrated under reduced pressure at 60° C. to a thick extract with a relative density of 1.20-1.30.

[0032] d) Dry the thick extract in a vacuum oven at 60°C to obtain a dry powder.

[0...

Embodiment 2

[0035] A composition of traditional Chinese medicine for treating gout comprises 60 parts of Cyclocarya paliurus, 25 parts of corn silk, 15 parts of kudzu root and 15 parts of Imperata rhizome in parts by weight.

[0036] The specific implementation steps are as follows:

[0037] a) Weigh 60 parts of Cyclocarya paliurus, 25 parts of corn silk, 15 parts of Pueraria lobata and 15 parts of Imperatae imperatae into an extraction tank, add distilled water 9 times the total mass of raw materials into the extraction tank, so that the distilled water fully immerses the raw material mixture.

[0038] b) Decocting at 80° C.-100° C. for 3 times, each time for 1-2 hours, filtering each filtrate while hot, and combining the filtrates of 3 times.

[0039] c) The combined filtrate is concentrated under reduced pressure at 60° C. to a thick extract with a relative density of 1.20-1.30.

[0040] d) Dry the thick extract in a vacuum oven at 60°C to obtain a dry powder.

[0041] e) Pack the dr...

Embodiment 3

[0043] A traditional Chinese medicine composition for treating gout comprises 80 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata root and 5 parts of Imperata rhizome in parts by weight.

[0044] The specific implementation steps are as follows:

[0045] a) Weigh 80 parts of Cyclocarya paliurus, 10 parts of corn silk, 5 parts of Pueraria lobata and 5 parts of Imperata prana in an extraction tank, add distilled water 10 times the total mass of raw materials into the extraction tank, so that the distilled water fully immerses the raw material mixture.

[0046] b) Decocting at 80° C.-100° C. for 3 times, each time for 1-2 hours, filtering each filtrate while hot, and combining the filtrates of 3 times.

[0047] c) The combined filtrate is concentrated under reduced pressure at 60° C. to a thick extract with a relative density of 1.20-1.30.

[0048] d) Dry the thick extract in a vacuum oven at 60°C to obtain a dry powder.

[0049] e) Pack the dry p...

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