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Measuring cell used for biomolecule detection

A technology of biomolecules and measuring pools, which is applied in the measurement of force measurement, measurement devices, and the measurement of the property force of piezoelectric resistance materials, etc., which can solve the problems of easy corrosion of chips and difficult replacement, reduce production costs and improve service life , cost reduction effect

Pending Publication Date: 2020-02-25
JIANGSU UNIV OF SCI & TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The invention provides a measuring cell for biomolecular detection to solve the technical problems that chips are easy to corrode and difficult to replace in the prior art

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  • Measuring cell used for biomolecule detection
  • Measuring cell used for biomolecule detection

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Embodiment Construction

[0017] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments It is a part of embodiments of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative efforts fall within the protection scope of the present invention.

[0018] Such as Figure 1-2 As shown, the embodiment of the present invention provides a measurement cell for biomolecular detection, including: a thermal insulation shell 1, a metal inner cavity 2, a sample liquid conduit 3, a transparent body 4, a cooling plate 5, a sealing ring 6, a quartz wafer 7, a top Electrode 8, bottom electrode 9, electrode terminal ...

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Abstract

The invention discloses a measuring cell used for biomolecule detection, which comprises a shell, an upper electrode, a lower electrode and a quartz wafer; the upper electrode is arranged at the top inside the shell; the lower electrode is arranged at the bottom inside the shell; and, the quartz wafer is arranged between the upper electrode and the lower electrode, and is not contacted with the upper electrode and the lower electrode. By adoption of the measuring cell provided by the invention, the electrode of the heteropolar chip is separated from the quartz wafer, so that the electrode is integrated into the measuring cell; thus, the chip is made of the quartz wafer; the cost of the raw material is low; the difficulty of the manufacturing technology low; and compared with the heteropolar chip, the manufacturing cost is greatly reduced.

Description

technical field [0001] The invention relates to the technical field of biomolecular detection, in particular to a measuring cell for non-polar QCM / LSPR dual technology biomolecular detection. Background technique [0002] In the existing QCM / LSPR (quartz crystal microbalance / localized surface plasmon resonance) dual-technology biomolecular detection measuring cell, the polar chip is obtained by integrating the quartz wafer and the electrode, and the required manufacturing process is difficult. Large, high cost, and the electrode is easily corroded by the sample liquid during measurement, and a new chip needs to be replaced. [0003] In the dual-technology biomolecular measurement cell of QCM / LSPR, QCM records the frequency change of the chip and the change speed of the fundamental frequency from oscillation to complete rest by intermittently opening / disconnecting the circuit; The spectral absorption exhibited, the localized surface plasmon resonance spectrum is obtained and...

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Application Information

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IPC IPC(8): G01N21/552G01L1/18
CPCG01N21/554G01L1/183
Inventor 朱琎周莉章佳军尹艳平王造极杨漪烨王宇王宝辉
Owner JIANGSU UNIV OF SCI & TECH