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Thanakha composition and preparation method and application thereof

A technology of composition and mixture, which is applied in the direction of pharmaceutical formulations, cosmetic preparations, toiletry preparations, etc., can solve the problem of single Tanaca products, achieve high-efficiency free radical scavenging activity, reduce the production of melanin, and promote development Effect

Active Publication Date: 2020-03-06
广州市络捷生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of this, the present invention provides a Tanaca composition and its preparation method and application, which are used to solve the relatively single problem of Tanaca products

Method used

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  • Thanakha composition and preparation method and application thereof
  • Thanakha composition and preparation method and application thereof
  • Thanakha composition and preparation method and application thereof

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preparation example Construction

[0049] The present invention also provides a preparation method of Tanaca composition, comprising the following steps:

[0050] a) mixing Tanaka, licorice and white fungus in a mass ratio of (10-90):(5-50):(5-50) to obtain a mixture;

[0051] b) extracting the mixture below 100°C to obtain a Tanaca composition.

[0052] In the present invention, Tanaca, licorice and white fungus are extracted at a temperature below 100°C, the active ingredients in the plants are retained, and the decomposition loss of the heat-sensitive active ingredients can be effectively reduced.

[0053] In the present invention, Tanaca, licorice and white fungus can be pulverized separately before mixing in step a), or pulverized after mixing in step a). At least 90% of the mixture in step a) can pass through a 800-mesh sieve.

[0054] Further, the extraction is microfluidic extraction.

[0055]Extract the broken Tanaca plant cells by micro-jet, and fully break the cells to extract the active ingredien...

Embodiment 1

[0093] Grind 7kg of Tanaka, 2kg of licorice root and 1kg of tremella slices, and pass through a sieve of 800 mesh to obtain a mixture with an average mesh of 800 mesh. Add 200kg of 60% 1,3-butanediol solution to the mixture, stir it evenly, put it into the micro-fluidic extractor, and extract it for 1 hour under the conditions of refrigerant temperature 20°C and feed rate 20L / min to obtain Tana card composition crude extract.

[0094] Pump the crude extract of the Tanaka composition into a centrifuge, perform a solid-liquid separation operation at a centrifugal speed of 10,000 rpm, and collect the separated liquid. Then the separated liquid is pumped into the membrane treatment system, and the impurity is removed using a 0.2 μm membrane, and finally concentrated to 1:5 (the mass of the medicinal material: the mass of the concentrated liquid), and the Tanaca composition is obtained.

Embodiment 2

[0096] Grind 8 kg of Tanaka, 1 kg of licorice root and 1 kg of tremella slices, and pass through a 400-mesh sieve to obtain a mixture with an average mesh number of 400 mesh. Add 400kg of 55% glycerol solution to the mixture, stir it evenly, put it into the micro-fluidic extractor, and extract it for 1.5h under the conditions of refrigerant temperature 10°C and feed rate 15L / min to obtain the Tanaca composition crude extract.

[0097] Pump the crude extract of the Tanaka composition into a centrifuge, perform a solid-liquid separation operation at a centrifugal speed of 15000 rpm, and collect the separated liquid. Then the separated liquid is pumped into the membrane treatment system, and the 0.1 μm membrane is used for impurity removal, and finally concentrated to 1:6 (the mass of the medicinal material: the mass of the concentrated liquid), and the Tanaca composition is obtained.

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Abstract

The invention belongs to the technical field of plant extraction, and particularly relates to a Thanakha composition and a preparation method and application thereof. The Thanakha composition comprises Thanakha, liquorice roots and tremella fuciformis. Experimental results show that the Thanakha, the liquorice roots and the tremella fuciformis in the Thanakha composition can achieve a synergisticeffect. In a tyrosinase in-vitro inhibition test, the composition can effectively inhibit the activity of tyrosinase and reduce the generation of melanin, so that the effects of beautifying and whitening are achieved; in a DPPH antioxidant test and ABTS free radical scavenging capacity determination, the composition shows efficient free radical scavenging activity, so that an anti-aging effect isachieved; in a UVB absorption capacity test, the composition shows an efficient sunscreen effect. The Thanakha composition with whitening, anti-aging and sun-screening effects is obtained by combiningthe Thanakha with the liquorice roots and the tremella fuciformis, the application of the Thanakha in cosmetics is promoted, and the development of Thanakha products is promoted.

Description

technical field [0001] The invention belongs to the technical field of plant extraction, and in particular relates to a Tanaca composition and its preparation method and application. Background technique [0002] Thanakhha is an alias of Hesperethusa crenulata (Roxb.) Roem, which belongs to the genus Rutaceae. In Myanmar, it mainly grows in dry and barren slope forests at an altitude of about 1,000 meters in the central and northern parts of Myanmar. Its bark contains Compounds such as polyphenols, flavanones, alkaloids, coumarins, lignans, sterols and triterpenoids have anti-inflammatory, bactericidal, anti-mosquito, and anti-ultraviolet damage effects. The leaf medicine is used to treat epilepsy, The root is used as a laxative, and the fruit is edible. In some areas of Myanmar and its neighboring countries, the bark is ground into powder and mixed with water to form a paste, which is applied externally on the skin as a sunscreen and beauty care product. [0003] In the t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9728A61Q19/02A61Q19/08A61Q17/04
CPCA61K8/9789A61K8/9728A61Q19/02A61Q19/08A61Q17/04A61K2800/5922Y02A50/30
Inventor 邹茜娜周锦珂彭颖华黄裕
Owner 广州市络捷生物科技有限公司
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