Storage agent, calibrator for detecting LH and detection kit

Abstract

The invention discloses a storage agent, a calibrator for detecting LH and a detection kit. The storage agent is used for stably storing antigens, and comprises 10-50 mmol / L of a buffer solution witha pH value of 5.5-8, 0.5-3 g / L of 8-aniline-1-naphthalene sulfonic acid and / or a salt thereof, 5-70 g / L of a protective agent, and 0.05-1 mL / L of a surfactant. The storage agent provided by the invention can stably store a plurality of antigens, shows excellent signal retention rate in an accelerated stability test, solves the problem that LH cannot be stored in a solution form for a long time, and avoids the problem of tedious detection steps caused by providing a calibration product in a freeze-drying form.

Description

technical field

[0001] The invention relates to a storage agent for stably preserving antigens in biochemical detection, in particular to a calibrator and a kit for stable storage in the detection of luteinizing hormone. Background technique

[0002] Luteinizing hormone (LH) is a glycoprotein hormone synthesized and secreted by the anterior pituitary gland and consists of two subunits, α and β. LH synthesis is regulated by sex hormone-releasing hormone (GnRH) in the hypothalamus, with feedback from steroid sex hormones. LH stimulates female ovulation and ovaries to secrete estrogen and progesterone; controls male testicular Leydig cells to secrete testosterone. In women, LH content is low during the follicular phase; it peaks in the middle of menstruation, triggering ovulation, and drops to a minimum after ovulation. LH is highest in postmenopausal women, even higher than the midmenstrual LH peak; LH levels are also high in gonadically ablated men. LH is important for the...

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