Combined drug for treating chronic, intractable or primary insomnia and application thereof

A stubborn and primary technology, applied in the field of biomedicine, can solve the problems of treating insomnia, shortening lifespan, and not being able to cure until it is cured, and achieves the effect of good application prospects.

Inactive Publication Date: 2020-05-12
李启芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] 3. Insomnia affects work, study and life
[0012] 6. Frequent insomnia causes premature aging and shortens life span
[0013] 7. Lack of sleep in children will affect the growth and development of the body
[0014] Drug therapy is the most sought-after treatment for many intractable insomnia patients, such as oral sleeping pills. However, the

Method used

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  • Combined drug for treating chronic, intractable or primary insomnia and application thereof

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Embodiment Construction

[0034] The "range" disclosed herein is in the form of lower and upper limits. There can be one or more lower limits, and one or more upper limits, respectively. The given range is defined by selecting a lower limit and an upper limit. The selected lower and upper limits define the boundaries of the particular range. All ranges that can be defined in this way are inclusive and combinable, that is, any lower limit can be combined with any upper limit to form a range. For example, the range of 60-120 and 80-110 is listed for specific parameters, and it is understood that the range of 60-110 and 80-120 is also expected. In addition, if the minimum range values ​​1 and 2 are listed, and if the maximum range values ​​3, 4, and 5 are listed, the following ranges can all be expected: 1-3, 1-4, 1-5, 2- 3. 2-4 and 2-5.

[0035] In the present invention, if there is no special description, all the embodiments and preferred embodiments mentioned herein can be combined with each other to ...

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Abstract

The invention provides a combined drug for treating chronic, intractable or primary insomnia. The combined drug comprises an anticholinergic drug and a sedative drug which are combined for use. According to the invention, the anticholinergic drug and the sedative drug are used according to a specific ratio, so the treatment effect can be effectively enhanced, and the morbidity of chronic, intractable or primary insomnia patients is delayed. The combined drug provided by the invention is small in side effects or free of side effects and high in safety. Meanwhile, the combined drug provided by the invention can effectively treat the chronic, intractable or primary insomnia; the effect of the combine drug is superior to the effect of dexmedetomidine for independent use; thus, the combined drug is indicated to have a synergistic effect in combined use in a specific ratio and have good clinical application prospect.

Description

Technical field [0001] The present invention belongs to the technical field of biomedicine, and specifically relates to combined drugs, including anticholinergic drugs and sedative drugs, for the treatment of chronic, intractable or primary insomnia. Background technique [0002] Insomnia is a sleep disorder characterized by frequent and continuous difficulty falling asleep and / or difficulty maintaining sleep, leading to unsatisfactory sleep. Insomnia can exist as an independent disease, or it can be comorbid with mental disorders, physical diseases or substance abuse, and can be accompanied by multiple functional impairments during awakening. [0003] Chronic insomnia refers to sleep disorder that lasts more than three days a week and lasts for at least three months. Small particle size negative ions have higher activity and can easily penetrate the human body and exert their healing and health care effects. [0004] Chronic insomnia is divided into primary insomnia and secondary i...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K31/46A61K31/5513A61K31/5517A61K31/05A61K31/4174A61P25/20
CPCA61K9/0019A61K31/05A61K31/4174A61K31/46A61K31/5513A61K31/5517A61K45/06A61P25/20A61K2300/00
Inventor 李启芳
Owner 李启芳
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