Combined drug for treating chronic, intractable or primary insomnia and application thereof

Abstract

The invention provides a combined drug for treating chronic, intractable or primary insomnia. The combined drug comprises an anticholinergic drug and a sedative drug which are combined for use. According to the invention, the anticholinergic drug and the sedative drug are used according to a specific ratio, so the treatment effect can be effectively enhanced, and the morbidity of chronic, intractable or primary insomnia patients is delayed. The combined drug provided by the invention is small in side effects or free of side effects and high in safety. Meanwhile, the combined drug provided by the invention can effectively treat the chronic, intractable or primary insomnia; the effect of the combine drug is superior to the effect of dexmedetomidine for independent use; thus, the combined drug is indicated to have a synergistic effect in combined use in a specific ratio and have good clinical application prospect.

Description

Technical field [0001] The present invention belongs to the technical field of biomedicine, and specifically relates to combined drugs, including anticholinergic drugs and sedative drugs, for the treatment of chronic, intractable or primary insomnia. Background technique [0002] Insomnia is a sleep disorder characterized by frequent and continuous difficulty falling asleep and / or difficulty maintaining sleep, leading to unsatisfactory sleep. Insomnia can exist as an independent disease, or it can be comorbid with mental disorders, physical diseases or substance abuse, and can be accompanied by multiple functional impairments during awakening. [0003] Chronic insomnia refers to sleep disorder that lasts more than three days a week and lasts for at least three months. Small particle size negative ions have higher activity and can easily penetrate the human body and exert their healing and health care effects. [0004] Chronic insomnia is divided into primary insomnia and secondary i...

AI Technical Summary

Problems solved by technology

[0009] 3. Insomnia affects work, study and life

[0012] 6. Frequent insomnia causes premature aging and shortens life span

[0013] 7. Lack of sleep in children will affect the growth and development of the body

[0014] Drug therapy is the most sought-after treatment for many intractable insomnia patients, such as oral sleeping pills. However, the addiction and dependence of these sleeping pills cannot completely help patients treat insomnia. Exacerbation of insomnia in patients

Acupuncture and moxibustion may relieve symptoms in the early stage of insomnia, but for patients with intractable insomnia and severe insomnia, the aggravation of the disease will not lead to a curative effect

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