Sodium alginate chewable tablets and preparation method thereof
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A technology of sodium alginate and chewable tablets, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, food science, etc., can solve problems such as hidden safety hazards, inability to meet and apply to various groups of people, and avoid excessive aluminum elements. , the preparation method is simple, and the effect is easy to carry
Inactive Publication Date: 2020-07-10
北京健讯医药科技有限公司
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[0005] Therefore, although the existing drugs can treat gastroesophageal reflux and common gastric disease
Method used
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Embodiment 1
[0036] A sodium alginate chewable tablet, comprising the following components by weight (mg): sodium alginate 200, sodium bicarbonate 300, calcium carbonate 150, magnesium oxide 300, D-mannitol 50, polyethylene glycol 6000 200, Hydroxypropyl Methyl Cellulose E50 5, Mint Flavor 10, Acesulfame K 1, Aspartame 3, Xylitol DC Grade 5, Magnesium Stearate 20.
[0037] A preparation method of sodium alginate chewable tablet, comprising the following steps:
[0038] (1) Weighing of raw materials: weigh each component according to the formula quantity, and set aside;
[0039] (2) Granulation:
[0040] (21) Polyethylene glycol 6000, hydroxypropyl methylcellulose and purified water are mixed into 20% and 5% concentration solutions, and used as adhesive for subsequent use;
[0041] (22) Mix the formula amount of sodium alginate, sodium bicarbonate, calcium carbonate, D-mannitol, acesulfame K, and aspartame evenly, add binder, and granulate with 30 mesh;
[0042] (3) Drying: dry the prepa...
Embodiment 2
[0047] A sodium alginate chewable tablet, comprising the following parts by weight (mg): sodium alginate 300, sodium bicarbonate 50, calcium carbonate 300, magnesium oxide 30, D-mannitol 300, polyethylene glycol 6000 50, Hydroxypropyl Methyl Cellulose E50 20, Mint Flavor 1, Acesulfame K 3, Aspartame 1, Xylitol DC Grade 100, Magnesium Stearate 5.
[0048] Its preparation method is with embodiment 1.
Embodiment 3
[0050] A sodium alginate chewable tablet, comprising the following components by weight (mg): sodium alginate 225, sodium bicarbonate 120, calcium carbonate 250, magnesium oxide 170, D-mannitol 220, polyethylene glycol 6000 100, Hydroxypropyl Methyl Cellulose E50 12, Peppermint Flavor 3, Acesulfame K 3, Aspartame 1, Xylitol DC Grade 50, Magnesium Stearate 10.
[0051] Its preparation method is with embodiment 1.
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Abstract
The invention discloses sodium alginate chewable tablets. The sodium alginate chewable tablets comprise the following components in parts by weight: 200-300 parts of sodium alginate, 50-300 parts of sodium bicarbonate, 150-300 parts of calcium carbonate, 30-300 parts of magnesium oxide, 50-300 parts of D-mannitol, 50-200 parts of polyethylene glycol 6000, 5-20 parts of hydroxypropyl methyl cellulose E50, 1-10 parts of peppermint essence, 1-3 parts of acesulfame potassium, 1-3 parts of aspartame, 5-100 parts of DC-grade xylitol, and 5-20 parts of magnesium stearate. The preparation method of the sodium alginate chewable tablets provided by the present application is simple, and the prepared chewable tablets can not only regulate gastroesophageal reflux and protect gastric mucosa, but also can supplement mineral elements calcium and magnesium at the same time, can also supplement zinc, and are suitable for a plurality of people; the sodium alginate chewable tablets are more convenient totake orally, and easy to carry; and the sodium alginate chewable tablets avoid the standard exceeding of aluminum elements and overdose of sodium elements, and can be used safely for a long time.
Description
technical field [0001] The invention relates to the technical fields of food and medicine, in particular to a sodium alginate chewable tablet and a preparation method thereof. Background technique [0002] Gastroesophageal reflux refers to a disease of clinical gastroesophageal reflux and esophageal mucosal damage caused by excessive contact (or exposure) of the gastroesophageal lumen to gastric juice. Abnormal reflux causes stomach contents to back up into the esophagus. The occurrence of gastroesophageal reflux and its complications is multifactorial, clinical manifestations are heartburn and acid reflux, dysphagia, dysphagia, nausea and so on. There will be major impacts on people's quality of life, such as depression, disturbed sleep, and impaired physical and social performance. Moreover, gastroesophageal reflux can also cause other diseases such as gastric ulcers. [0003] Traditional drugs for gastroesophageal reflux are mainly sodium bicarbonate, calcium carbonate...
Claims
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