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A traditional Chinese medicine composition for treating dysmenorrhea due to luteal insufficiency and its preparation method and application

A technology of insufficiency and composition, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems that have not been used to treat dysmenorrhea due to luteal insufficiency, and improve uterine ischemia and hypoxia status, reduced PAF level, good safety effect

Active Publication Date: 2021-11-23
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The traditional Chinese medicine composition disclosed in the applicant's previous patent 2014107986331 is mainly used to treat infertility and menstrual disorders of luteal phase insufficiency, but not for the treatment of luteal phase insufficiency dysmenorrhea

Method used

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  • A traditional Chinese medicine composition for treating dysmenorrhea due to luteal insufficiency and its preparation method and application
  • A traditional Chinese medicine composition for treating dysmenorrhea due to luteal insufficiency and its preparation method and application
  • A traditional Chinese medicine composition for treating dysmenorrhea due to luteal insufficiency and its preparation method and application

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Experimental program
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Effect test

Embodiment 1

[0032] 1. A traditional Chinese medicine composition for treating dysmenorrhea due to corpus luteum insufficiency, which is made from the following raw materials in parts by weight:

[0033] 10 grams of rhizoma cyperi, 10 grams of mugwort leaves, 10 grams of fennel, 20 grams of kudzu root, 5 grams of cinnamon,

[0034] 10 grams of antler slices, 15 grams of yam, 15 grams of dodder, 10 grams of paeonol, 10 grams of salvia,

[0035] 10 grams of trigonum, 10 grams of curcuma.

[0036] 2. A method for preparing a Chinese medicinal composition for treating dysmenorrhea due to corpus luteum insufficiency, comprising the following steps:

[0037] Take 10 grams of Cyperus cyperi, 10 grams of mugwort leaves, 10 grams of fennel, 20 grams of kudzu root, 5 grams of cinnamon, 10 grams of antler slices, 15 grams of yam, 15 grams of dodder, 10 grams of paeonol, 10 grams of salvia miltiorrhiza, and 10 grams of triangular 10 grams of Curcuma, soaked in water for 1 hour, put it in a multi-funct...

Embodiment 2

[0039] 1. A traditional Chinese medicine composition for treating dysmenorrhea due to corpus luteum insufficiency, which is made from the following raw materials in parts by weight:

[0040] 30 grams of Cyperus cyperi, 30 grams of Artemisia argyi, 30 grams of cumin, 60 grams of kudzu root, 15 grams of cinnamon, 30 grams of antler slices, 45 grams of Chinese yam, 45 grams of dodder, 30 grams of paeonol, 30 grams of salvia miltiorrhiza, 30 grams of trigonum, Curcuma 30 grams.

[0041] 2. A method for preparing a Chinese medicinal composition for treating dysmenorrhea due to corpus luteum insufficiency, comprising the following steps:

[0042] Take 30 grams of Cyperus cyperi, 30 grams of mugwort leaves, 30 grams of cumin, 60 grams of kudzu root, 15 grams of cinnamon, 30 grams of antler slices, 45 grams of yam, 45 grams of dodder, 30 grams of paeonol, 30 grams of salvia miltiorrhiza, and 30 grams of triangular 1. 30 grams of curcuma, soak in water for 1 hour, put it in a multi-fu...

Embodiment 3

[0044] 1. A traditional Chinese medicine composition for treating dysmenorrhea due to corpus luteum insufficiency, which is made from the following raw materials in parts by weight:

[0045] 60 grams of cyperus, 60 grams of mugwort leaves, 60 grams of fennel, 120 grams of kudzu root, 30 grams of cinnamon, 60 grams of antler slices, 90 grams of yam, 90 grams of dodder, 60 grams of paeonol, 60 grams of salvia, 60 grams of triangular, Curcuma 60 grams.

[0046] 2. A method for preparing a Chinese medicinal composition for treating dysmenorrhea due to corpus luteum insufficiency, comprising the following steps:

[0047] Take 60 grams of Cyperus cyperi, 60 grams of mugwort leaves, 60 grams of cumin, 120 grams of kudzu root, 30 grams of cinnamon, 60 grams of antler slices, 90 grams of yam, 90 grams of dodder, 60 grams of paeonol, 60 grams of salvia miltiorrhiza, and 60 grams of triangular 60 grams of Zedoary Curcuma, soak for 2 hours in water with 10 times the total amount of medic...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating dysmenorrhea due to corpus luteum insufficiency and its preparation method and application. ~120 parts, 5~30 parts of cinnamon, 10~60 parts of antler slices, 15~90 parts of Chinese yam, 15~90 parts of Cuscuta seed, 10~60 parts of paeonol, 10~60 parts of salvia miltiorrhiza, 10~60 parts of trigonum and curcuma 10 to 60 parts. The present invention screens and obtains prescriptions through a large number of experiments. The experimental results show that the traditional Chinese medicine composition can reduce the degree of dysmenorrhea, reduce VAS scores, improve dysmenorrhea symptoms, TCM symptoms, and BBT curves; and can reduce PGF secreted by endometrium. 2α , ET secreted by vascular endothelial cells, serum PAF, increase serum LXA4 content; can regulate the level of sex hormones in the mid-luteal phase, improve ovarian and uterine artery blood flow, endometrial receptivity, and finally improve luteal function and relieve uterine ischemia and hypoxia , relieve pain, have a good effect on treating dysmenorrhea, and have no toxic and side effects, and the medicine is safe and reliable.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating dysmenorrhea due to corpus luteum insufficiency, a preparation method and application thereof. Background technique [0002] Dysmenorrhea is a common and frequently-occurring disease in gynecology. It refers to lower abdominal pain, swelling, and even pain in the lumbosacral area before and after menstruation or during menstruation. Jue cold and other symptoms. The global incidence of dysmenorrhea is about 17% to 80%, and it is increasing year by year. It is closely related to absenteeism, absenteeism and other daily activities, which adversely affects work and life. Modern medicine has expounded a lot on the pathogenesis of dysmenorrhea, but the understanding has not been unified and perfected, and the treatment method is relatively simple. The treatment of modern medicine for dysmenorrhea: one is to reduce the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P15/00A61P29/00A61K35/32
CPCA61K35/32A61K36/235A61K36/282A61K36/39A61K36/43A61K36/488A61K36/537A61K36/54A61K36/65A61K36/71A61K36/8905A61K36/8945A61K36/902A61K36/9066A61K2236/331A61K2236/39A61P15/00A61P29/00A61K2300/00
Inventor 周惠芳谈津婷刘贝胡明慧周维叶夏亲华洪艳丽刘音吟刘志辉王琼
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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