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Application of composition containing hyaluronic acid and polyol in improving water-soluble vitamin skin permeability

A technology of water-soluble vitamins and hyaluronic acid, applied in the field of beauty and skin care, can solve problems such as increasing the risk of infection and puncturing the skin, and achieve the effects of clear pharmacological and pharmacological properties, product safety, and free radical scavenging.

Active Publication Date: 2020-08-21
BLOOMAGE BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

First, these methods require professional equipment, and second, some need to puncture the skin, which increases the risk of infection

Method used

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  • Application of composition containing hyaluronic acid and polyol in improving water-soluble vitamin skin permeability
  • Application of composition containing hyaluronic acid and polyol in improving water-soluble vitamin skin permeability
  • Application of composition containing hyaluronic acid and polyol in improving water-soluble vitamin skin permeability

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] A compound solution for anti-aging skin, the content of each component is as follows (wt%): oligomeric sodium hyaluronate (90,000 Da) 0.1%; low molecular weight sodium hyaluronate (900,000 Da) 0.1%; high molecular weight hyaluronic acid Sodium acid (2.6 million Da) 0.3%; polyol antioxidant glycerin 0.1%, mannitol 0.1%, sorbitol 0.1%; glycine 0.0005%, proline 0.0005%; vitamin B 2 0.0005%; the balance of purified water.

Embodiment 2

[0056] A compound solution for anti-aging skin, the content of each component is as follows (wt%): oligomeric sodium hyaluronate (03,000 Da) 1%; low molecular weight sodium hyaluronate (50,000 Da) 1%; high molecular weight hyaluronic acid sodium phosphate (1.1 million Da) 2%; polyol antioxidant glycerin 3%; water-soluble amino acids 5%: of which, glycine 0.75%, proline 0.1%, hydroxyproline 0.4%, lysine hydrochloride 0.43 %, Isoleucine 0.35%, Leucine 0.09%, Serine 0.1%, Alanine 0.2%, Aspartic Acid 0.25%, Tyrosine 0.025%, Glutamic Acid 0.075%, Phenylalanine 0.53% , Arginine Hydrochloride 0.5%, Valine 0.36%, Threonine 0.25%, Histidine Hydrochloride 0.25%, Tryptophan 0.09%, Methionine 0.22%, Cystine 0.01%, Cysteine 0.02%; water-soluble vitamins total 0.5%: Among them, vitamin B 1 0.05%, vitamin B 2 0.05%, Niacinamide 0.05%, Vitamin B 6 0.05%, vitamin B 12 0.05%, folic acid 0.05%, vitamin C 0.2%; purified water balance.

Embodiment 3

[0058] A compound solution for anti-aging skin, the content of each component is as follows (wt%): oligomeric sodium hyaluronate (70,000 Da) 0.3%; low molecular weight sodium hyaluronate (500,000 Da) 0.3%; high molecular weight hyaluronic acid Sodium acid (2 million Da) 0.3%; polyol antioxidant mannitol 0.5%; glycine 0.0005%, proline 0.0005%; vitamin B 2 0.0005%; the balance of purified water.

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Abstract

The invention discloses an application of a composition containing hyaluronic acid and a polyol in improving the skin permeability of water-soluble vitamins. The composition comprises oligomeric hyaluronic acid or a salt thereof, low molecular weight hyaluronic acid or a salt thereof, high molecular weight hyaluronic acid or a salt thereof and a polyol antioxidant. The components are common raw materials in medicine, pharmacological and pharmacokinetic properties are clear, and the product is safe. According to the invention, hyaluronic acid or the salt thereof is compounded and combined withthe polyol antioxidant, the effects of moisturizing, scavenging free radicals and resisting aging are achieved, and the transdermal absorption of water-soluble vitamins can be improved, so that the water-soluble vitamins can be absorbed into epidermis and corium layers without professional equipment or a skin piercing method, and are accumulated in the epidermis and corium layers to continuously provide nutrition for the skin, thereby fully exerting the skin care and beautifying effects.

Description

technical field [0001] The present invention relates to a composition containing hyaluronic acid and polyhydric alcohols, and also relates to the application of the composition in improving the skin permeability of water-soluble vitamins / water-soluble amino acids and the composition containing hyaluronic acid, polyhydric alcohols, water-soluble vitamins / The anti-aging skin product of water-soluble amino acid belongs to the technical field of beauty and skin care. Background technique [0002] With the development of the economy and the progress of the society, people pay more and more attention to the external image. Due to the strong psychological effect of the superficial exposure of the skin, delaying skin aging has gradually become one of the hot spots that people pay attention to. Among them, the most commonly used, most widely accepted, and safest anti-aging means of skin is to apply skin care products. The active ingredients in skin care products include water-solub...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/34A61K8/44A61K8/49A61K8/67A61Q19/08
CPCA61K8/735A61K8/345A61K8/44A61K8/4913A61K8/492A61K8/4946A61K8/447A61K8/673A61K8/675A61K8/676A61Q19/08A61K2800/5922
Inventor 杨莹莹张燕刘建建郭学平
Owner BLOOMAGE BIOTECHNOLOGY CORP LTD
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