Animal model intestinal tract pathology sampling and cleaning probe

Abstract

The invention provides an animal model intestinal tract pathology sampling and cleaning probe, and belongs to the field of biomedical instruments. The animal model intestinal tract pathology samplingand cleaning probe comprises a hollow extension pipe, an adjustable probe and a discharge channel, wherein a plurality of first liquid inlet pipes are uniformly arranged on the side wall of the hollowextension pipe; the adjustable probe is arranged at one end of the extension pipe and comprises a plurality of blade assemblies which are sequentially overlaid, covered and encircled into a ring; thedischarge channel consists of the extension pipe and an adjustable probe and is used for discharging intestinal contents; each blade assembly is rotatably arranged on the corresponding first liquid inlet pipe; a second liquid inlet pipe is arranged on each blade assembly, and communicates with the corresponding first liquid inlet pipe; and along with synchronous rotation of the blade assemblies,the inner diameter of one end of the discharging channel is sequentially decreased or increased. According to the probe, after animal models such as mice are established, contents can be taken out andthe inner wall of the intestinal tract can be cleaned under the condition of not damaging the original pathological performance of the intestinal tract or killing the mice.

Description

technical field [0001] The invention belongs to the field of biomedical equipment, and in particular relates to a probe for collecting and cleaning intestinal pathology of an animal model. Background technique [0002] After the animal model is established, in order to analyze the changes in the intestinal contents or clean up the intestinal contents, it is usually necessary to remove the contents and clean the inner wall of the intestinal tract without destroying the original pathological manifestations of the intestinal tract. [0003] For example, after the establishment of the Parkinson's mouse model, it is usually accompanied by constipation and changes in the intestinal flora, so the sampling and analysis of intestinal contents can be used to determine the changes in the intestinal flora, so as to monitor the pathology of the Parkinson's model process etc. However, the conventional method needs to kill the mouse model, so it is impossible to obtain the dynamic data of...

AI Technical Summary

Problems solved by technology

[0006] The second is that the eversion method can ensure the integrity of the specimen, but it has high technical requirements for the operator, and it is easy to cause mechanical damage to the specimen

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