2019-nCoV double-target antibody detection microsphere complex combination, preparation method, kit and use method of kit

Abstract

The invention relates to the technical field of virus detection, and particularly discloses a novel coronavirus 2019-nCoV double-target antibody detection microsphere complex combination, a preparation method, a kit and a using method of the kit. A microsphere complex combination coupled with an antigen is used; the coupling antigen comprises an S protein of the novel coronavirus 2019-nCoV and anN protein of the novel coronavirus 2019-nCoV, the amino acid sequence of the S protein is as shown in SEQ NO: 1, and the amino acid sequence of the N protein is as shown in SEQ NO: 2. The prepared microsphere complex combination can perform double-target detection on an S antibody and an N antibody, and fully reflects the effect that two main antigens of the novel coronavirus (2019-nCoV) stimulatean organism to generate a specific antibody.

Description

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AI Technical Summary

Benefits of technology

This patented technology allows researchers to study how different viruses cause diseases like COVID-19. It uses specialized particles called microparticles made from glass flakes containing rare earth elements (RE). These tiny objects have unique properties such as being able to target both virus types simultaneously without causing harmful side reactions when they infect humans. They also allow for precise analysis of their presence through flow cysmography measurements. Overall, this technology provides an effective way to identify unknown agents caused by these bacteria.

Problems solved by technology

This patented technical problem addressed in this patents relating to genetic testing identifies new viruses called Coronvirus or NovelCorona Virus (NCV) based on their similarity between certain sequences found near opposite endings of two different strain groups. These differences help identify potential sources of these diseases through various techniques such as reverse transcriptase polymerization amplification assays, sequencing methods, Western blotting, mass spectrometry, etc., making it possible to develop effective treatments targeting specific disease states associated therewith.

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