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Positioning calibration device and method for automatic nucleic acid extraction equipment

A technology for extracting equipment and calibrating devices, which is applied in image data processing, instruments, calculations, etc., can solve the problems of customers' economic losses and high labor costs, and achieve the effect of improving accuracy and reducing costs

Pending Publication Date: 2020-11-17
SHANGHAI RENDU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the one hand, the manual calibration error caused by different calibrators is also a factor of manipulator offset. On the other hand, it is expensive to go to the customer's site for calibration from time to time. On the other hand, the calibration time lag will cause certain economic losses to the customer.

Method used

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  • Positioning calibration device and method for automatic nucleic acid extraction equipment
  • Positioning calibration device and method for automatic nucleic acid extraction equipment
  • Positioning calibration device and method for automatic nucleic acid extraction equipment

Examples

Experimental program
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Embodiment 1

[0043] This embodiment aims at the problem that the existing nucleic acid extraction equipment adopts the method of manual calibration, and there is a problem that the deviation causes the manipulator to shift. It provides an automatic calibration of the position of the manipulator, and real-time calibration of the position accuracy, so as to improve the accuracy of the manipulator. Accurate positioning calibration device for automated nucleic acid extraction equipment.

[0044] Such as figure 1 , 2 As shown, the positioning calibration device for automatic nucleic acid extraction equipment includes: a platform 6 , a bracket 5 , a robotic arm 3 , a robotic arm 4 , an image collector 1 and a controller 7 . Wherein, the platform 6 is divided into a plurality of module areas 8 with different functions and structures, and different containers or suction heads are placed in different module areas 8 . The bracket 5 is vertically fixed on one side of the platform 6 for supporting t...

Embodiment 2

[0052] This embodiment provides a method for positioning and calibrating a manipulator, which is used in the positioning and calibrating device of the automated nucleic acid extraction equipment in Embodiment 1. Please see image 3 , the manipulator positioning calibration method, including:

[0053] S1: collect the position of the tip or the container in the positioning area, select the target tip or the target container from it, and use the position of the target tip or the target container as the preset positioning point;

[0054] S2: Move the manipulator above the preset positioning point, and collect an image of the positioning area below as a standard image;

[0055] S3: During the positioning and calibration of the manipulator, move the manipulator above the preset positioning point, and collect an image of the positioning area below as a real-time image;

[0056] S4: judging whether the real-time image overlaps with the standard image, if they overlap, use the preset...

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Abstract

The invention discloses a positioning calibration device and method for automatic nucleic acid extraction equipment, and aims to solve the problem of manipulator deviation caused by deviation of existing nucleic acid extraction equipment due to adoption of a manual calibration method. A controller is electrically connected with a mechanical arm and a manipulator, and movement of the mechanical armand the manipulator is controlled; meanwhile, the controller is electrically connected with an image collector and used for receiving the image information output by the image collector, comparing the image information with a pre-stored image of a corresponding module area, sending a corresponding instruction to the mechanical arm or the mechanical arm according to a comparison result, automatically calibrating the walking position of the mechanical arm and calibrating the walking precision in real time, therefore, the manipulator moving accuracy is improved, and the cost is reduced.

Description

technical field [0001] The invention belongs to the field of extraction and purification equipment for nucleic acid detection of human samples, and in particular relates to a positioning and calibration device and method for automatic nucleic acid extraction equipment. Background technique [0002] The nucleic acid detection of human samples is firstly to extract and purify the collected human samples. Now the extraction and purification process is basically completed by automatic instruments, replacing manual work, which not only improves the accuracy of detection, but also realizes batch detection and work efficiency. [0003] When the automated instrument extracts and purifies samples, the manipulator moves along with the manipulator in various areas to sample and add samples continuously. The displacement control and accuracy of the manipulator may be stuck due to reasons such as the mechanical structure, drive motor, and guide rails. Out of step, long-term movement tens...

Claims

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Application Information

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IPC IPC(8): G06T7/00G06T7/70
CPCG06T7/0004G06T7/0002G06T7/70
Inventor 居金良朱汉敏赵玉军金浩党强
Owner SHANGHAI RENDU BIOTECH
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