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Traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, traditional Chinese medicine preparation and application

A technology of osteoporosis and composition, which is applied in the direction of drug combination, medical preparations containing active ingredients, bone diseases, etc., and can solve problems such as ineffective treatment of osteoporosis

Pending Publication Date: 2020-11-27
INNER MONGOLIA MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment effect on osteoporosis caused by breast cancer treatment is not obvious

Method used

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  • Traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, traditional Chinese medicine preparation and application
  • Traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, traditional Chinese medicine preparation and application
  • Traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, traditional Chinese medicine preparation and application

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Effect test

Embodiment 1

[0025] A traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, said composition comprising the following components: Rehmannia glutinosa 28g, Cornus officinalis 8g, Chinese yam 16g, wolfberry 8g, tortoise shell glue 16g, antler glue 8g, Dipsacus 13g , Drynaria 5g, Dodder 16g, Achyranthes bidentata 5g, Angelica 13g, Radix Paeoniae Alba 8g, Woody 5g.

Embodiment 2

[0027] A traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, said composition comprising the following components: Rehmannia glutinosa 20g, Cornus officinalis 16g, Chinese yam 8g, wolfberry 16g, tortoise shell glue 8g, antler glue 16g, Dipsacus 5g , Drynaria 13g, Dodder 8g, Achyranthes bidentata 13g, Angelica 5g, Radix Paeoniae Alba 16g, Woody 1g.

Embodiment 3

[0029] A traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, said composition comprising the following components: Rehmannia glutinosa 27g, Cornus officinalis 9g, Chinese yam 15g, wolfberry 9g, tortoise shell glue 15g, antler glue 9g, Dipsacus 12g , drynaria 6g, dodder 15g, achyranthes bidentata 6g, angelica 12g, white peony 9g, woody 5g.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, and relates to the technical field of traditional Chinese medicines. Thetraditional Chinese medicine composition comprises 20-28 parts of prepared rehmannia roots, 8-16 parts of cornus officinalis, 8-16 parts of Chinese yam, 8-16 parts of Chinese wolfberry fruits, 8-16 parts of tortoise-plastron glue, 8-16 parts of deer-horn glue, 5-13 parts of teasel roots, 5-13 parts of rhizoma drynariae, 8-16 parts of semen cuscutae, 5-13 parts of achyranthes bidentata, 5-13 partsof angelica sinensis, 8-16 parts of white peony roots and 1-5 parts of radix aucklandiae. The composition can obviously improve the levels of estradiol (E2) and bone transition markers BALP and P1NPin serum in the treatment process of breast cancer mice, bone mineral density is improved, the effect is superior to that of alendronate sodium and zuogui pills, and the composition has a remarkable effect on treating osteoporosis caused by breast cancer treatment.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating osteoporosis caused by breast cancer treatment, a traditional Chinese medicine preparation and application. Background technique [0002] Osteoporosis is a systemic skeletal disease characterized by low bone mass, damaged bone microarchitecture, decreased bone strength, and susceptibility to fractures. Studies have shown that endocrine therapy can effectively improve the survival rate of breast cancer patients, but it will lead to a decrease in bone density and increase the occurrence of osteoporosis and pathological fractures. Studies by Wu Peili and others have shown that osteoporosis in patients with breast cancer after treatment The disease rate reaches 40.8%. Bisphosphonates are commonly used clinical anti-osteoporosis drugs, which are relatively expensive, and long-term use can lead to adverse rea...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P19/10A61P35/00A61K35/586A61K35/32
CPCA61K35/32A61K35/586A61K36/126A61K36/185A61K36/21A61K36/232A61K36/285A61K36/39A61K36/40A61K36/43A61K36/65A61K36/71A61K36/804A61K36/815A61K36/8945A61P19/10A61P35/00A61K2300/00
Inventor 刘春慧董秋梅
Owner INNER MONGOLIA MEDICAL UNIV
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