A halbach magnet for non-invasive nuclear magnetic resonance detection of human finger blood glucose
A nuclear magnetic resonance and finger technology, applied in the fields of electromagnetics, medical diagnosis and screening, to achieve the effect of optimizing accuracy error, highly stable performance, and high central magnetic field strength
Active Publication Date: 2022-06-17
SOUTHEAST UNIV
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However, among the permanent magnet structures used, there is no high-performance NMR magnet structure suitable for finger samples
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[0058] The present invention will be described in further detail below with reference to the accompanying drawings and specific preferred embodiments.
[0059] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "left side", "right side", "upper", "lower part", etc. are based on the orientation or positional relationship shown in the drawings, only For the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a particular orientation, be constructed and operate in a particular orientation, "first", "second", etc. importance, and therefore should not be construed as a limitation to the present invention. The specific dimensions used in this embodiment are only for illustrating the technical solution, and do not limit the protection scope of the present invention.
[0060] like figure...
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The invention discloses a Halbach magnet for non-invasive nuclear magnetic resonance detection of human finger blood sugar, which comprises a main magnet, a three-layer shimming ring, a shimming sheet, a double-layer heat insulation device and a temperature control assembly. The main magnet is a trapezoidal magnetic steel and a rectangular magnetic steel placed at intervals in a hexagonal shape. The three-layer shim ring is symmetrically distributed along the central horizontal plane on the inner side of the main magnet. There are three upper and lower layers, and there is an axial shim gap in the middle. The optimal structural parameters are obtained by pattern search algorithm optimization and finite element simulation analysis. . The shim sheet is glued on the moving positioning structure of the shim sheet, which can precisely adjust the spatial position of the shim sheet. The optimal position of the shim sheet is obtained through polynomial fitting, simulation parameter optimization, and algorithm optimization to ensure high uniformity of the magnetic field. sex and stability. The design of the magnet of the present invention is highly suitable for finger samples, and produces a relatively high magnetic field strength (1T), with excellent uniformity, and satisfies the implementation conditions of analysis methods such as relaxation analysis and magnetic resonance imaging for finger detection.
Description
technical field [0001] The invention relates to the fields of electromagnetism, medical diagnosis, screening and the like, in particular to a Halbach magnet used for non-invasive nuclear magnetic resonance detection of human finger blood sugar. Background technique [0002] With the change of living habits, the incidence of diabetes is increasing year by year. According to the latest statistics from the International Diabetes Federation, as of 2013, there were 238.2 million people with diabetes in the world, and the number of people with diabetes is expected to increase to 592 million by 2035. In China, the incidence of diabetes reached 9.7%. Therefore, the prevention and treatment of diabetes has important social value. Blood glucose concentration is the main basis for judging diabetes. At present, the commonly used methods for blood glucose detection in clinical practice are blood biochemical analysis after needle blood draw or finger puncture. The biochemical analyzer...
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IPC IPC(8): G01R33/38A61B5/055A61B5/145
CPCG01R33/3802A61B5/055A61B5/14532
Inventor 易红陆荣生王俊楠吴正秀张金翔
Owner SOUTHEAST UNIV