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Skin care composition with synergistic anti-aging effect and its preparation method and application

A skin care composition and extract technology, applied in the field of cosmetics, can solve the problems of skin irritation, reduce the depth of deep wrinkles, no obvious positive effect, etc., and achieve the effect of increasing skin elasticity

Active Publication Date: 2021-05-07
广州美神生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when it is used at a suitable or recommended content (5.0%), it often produces greater irritation to the skin, and the skin may appear discomfort symptoms such as tingling, burning, redness and swelling, and it has been proved to be effective in reducing deep wrinkles when acting alone. No significant positive effect of depth
[0005] The bark extract of the flower palm, which is rich in Pterocarpus stilbene, has excellent anti-oxidation, whitening, anti-inflammatory and anti-ultraviolet effects. It is often used as a whitening active ingredient, and it has not been used in anti-aging and wrinkle removal. use

Method used

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  • Skin care composition with synergistic anti-aging effect and its preparation method and application
  • Skin care composition with synergistic anti-aging effect and its preparation method and application
  • Skin care composition with synergistic anti-aging effect and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1, skin care composition

[0044] Preparation of Tomato / Yeast Ferment Filtrate

[0045] S1. Take fresh tomatoes, crush the tissue, filter out the juice, concentrate to dryness under reduced pressure, add 70% acetone solution, extract for 3 hours, filter, and concentrate under reduced pressure to obtain tomato extract;

[0046]S2, add the tomato extract of its volume 16% to the yeast fermentation medium, sterilize; Insert Candida utilis after seed culture by 5% inoculation amount, be 28 ℃ at fermentation temperature, rotating speed is 160r Cultivate for 4 days under the condition of aeration rate of 1-4VVM, filter, take the fermentation broth, centrifuge at 4000r / min, remove the supernatant, and grind the centrifuge for 0.5h;

[0047] S3. Add 3 times the weight of deionized water to the ground centrifuge, mix evenly, extract for 3 hours, and filter to obtain the tomato / yeast fermentation product filtrate.

[0048] The skin care composition described in Examp...

Embodiment 2

[0049] Embodiment 2, skin care composition

[0050] Preparation of Tomato / Yeast Ferment Filtrate

[0051] S1. Take fresh tomato, crush the tissue, filter out the juice, concentrate to dryness under reduced pressure, add 50% acetone solution, extract for 2 hours, filter, and concentrate under reduced pressure to obtain tomato extract;

[0052] S2, add the tomato extract of its volume 20% to the yeast fermentation medium, sterilize; Insert Candida utilis after seed culture by 5% inoculum size, be 28 ℃ at fermentation temperature, rotating speed is 180r Cultivate for 5 days under the condition of aeration of 1-4VVM, filter, take the fermentation broth, centrifuge at 4000r / min, remove the supernatant, and grind the centrifuge for 0.5h;

[0053] S3. Add 5 times the weight of deionized water to the ground centrifuge, mix evenly, extract for 2 hours, and filter to obtain the tomato / yeast fermentation product filtrate.

[0054] The skin care composition described in Example 2 is com...

Embodiment 3

[0055] Embodiment 3, skin care composition

[0056] Preparation of Tomato / Yeast Ferment Filtrate

[0057] S1. Take fresh tomatoes, crush the tissues, filter out the juice, concentrate to dryness under reduced pressure, add 60% acetone solution, extract for 3 hours, filter, and concentrate under reduced pressure to obtain tomato extract;

[0058] S2, add the tomato extract of its volume 12% to yeast fermentation culture medium, sterilize; Insert Candida utilis after seed culture by 5% inoculum size, be 28 ℃ at fermentation temperature, rotating speed is 150r Cultivate for 3 days under the condition of aeration of 1-4VVM, filter, take the fermentation broth, centrifuge at 4000r / min, remove the supernatant, and grind the centrifuge for 0.5h;

[0059] S3. Add 5 times the weight of deionized water to the ground centrifuge, mix evenly, extract for 3 hours, and filter to obtain the tomato / yeast fermentation product filtrate.

[0060] The skin care composition described in Example 3...

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PUM

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Abstract

The invention belongs to the technical field of cosmetics, and specifically relates to a skin care composition with a synergistic anti-aging effect, which comprises: about 3-5 parts by weight of γ-aminobutyric acid; and about 1 to 20 parts by weight of the tomato / yeast fermentation product filtrate. The skin care composition provided by the present invention is composed of γ-aminobutyric acid, flower palm bark extract and tomato / yeast fermentation product filtrate. The anti-aging effect of each component is tested individually and in combination, and the combined use of the three It has a stronger effect on reducing the number, depth, length, area of ​​wrinkles and improving skin elasticity, which proves that the three have achieved a significant synergistic effect on anti-aging; secondly, by testing γ‑aminobutyric acid, γ‑amino Skin irritation of butyric acid + flower palm bark extract + tomato / yeast ferment filtrate group, the test showed that the latter showed hyposensitivity properties, showing that the combination of the three overcomes 5% GABA There is a bigger irritating problem when used alone.

Description

technical field [0001] The invention belongs to the technical field of cosmetics. More specifically, it relates to a skin care composition with synergistic anti-aging effect and its preparation method and application. Background technique [0002] External factors such as ultraviolet rays and expression extrusion can easily stimulate the excessive secretion of neutrophil elastase in the dermis of the skin, which will cause excessive decomposition of collagen and elastin in the skin and cause deep wrinkles. At present, retinol, Bosein, etc. are mainly used on the market to achieve the effect of anti-wrinkle, but most of them are only effective for shallow skin wrinkles, but have little effect on improving deep wrinkles. For example, the Purple Iron Essence of L’Oreal Group uses Bose as the main anti-wrinkle and anti-aging ingredient, combined with high-concentration hyaluronic acid, to achieve the effect of promoting collagen production and accelerating skin regeneration. Ho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/44A61K8/9789A61K8/9728A61Q19/08
CPCA61K8/44A61K2800/5922A61K2800/85A61Q19/08A61K8/9728A61K8/9789
Inventor 何军梁其文
Owner 广州美神生物科技有限公司