A composite tendon repair material and its preparation method

Abstract

The invention relates to a composite tendon repair material, characterized in that the composite tendon repair material includes a base layer and at least one active unit; the base layer and the at least one active unit are fixed to each other; the base layer includes an extracellular matrix material ; Each active unit in the at least one active unit comprises a first active layer, a second active layer and a cover layer respectively; the first active layer comprises an extracellular matrix material and a first active component; the second active The layer comprises an extracellular matrix material and a second active ingredient; each active unit is prepared by mechanical compression. The repair material promotes the growth and repair of bone tissue wound and the growth and repair of tendon tissue wound at the tear of tendon and bone respectively, and finally promotes the healing of the junction of tendon and bone, effectively forming a transition from bone, calcified cartilage, fibrocartilage to Insertion-like structure of the tendon. This construct will enable the repair of giant rotator cuff tendon tears.

Description

A kind of composite tendon repair material and preparation method thereof technical field The present invention relates to medical implant medical device, be specifically related to a kind of tendon repair material with composite structure, the The material has a growth factor with a quantitative gradient change per unit length, which effectively realizes the establishment of tendon-bone insertion points, and the preservation of tendons. Effective repair. The present invention further includes a preparation method of the composite tendon repair sheet material. Background technique Rotator cuff is the sleeve formed by the tendon of supraspinatus, infraspinatus, subscapularis, teres minor in front of humeral head, on top, behind The sleeve-like muscle-like structure realizes the functions of controlling and rotating the arm. The rotator cuff tendon becomes inflamed and degraded when overloaded It causes pain, lipidation, and calcification, which reduces the mechanica...

AI Technical Summary

Problems solved by technology

However, pathological studies have shown that the tissue structure of the rotator cuff insertion cannot return to its normal shape after surgical reconstruction, and the main problem is that the fibrocartilage layer in the healed tendon-bone interface cannot be regenerated and is only replaced by scar tissue, resulting in the formation of an indirect insertion. The mechanical properties of the point are far lower than the normal direct stop, and it is easy to re-tear

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