Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A composite tendon repair material and its preparation method

A repair material and a part of the technology, applied in the direction of muscles, ligaments, prostheses, etc., can solve the problems of non-recovery of the tissue structure of the rotator cuff insertion point, low mechanical properties of the indirect insertion point, and inability to regenerate the fibrocartilage layer, so as to achieve active induction of tissue. Regenerate, achieve reconstruction, avoid cutting effects

Active Publication Date: 2022-05-31
BEIJING BIOSIS HEALING BIOLOGICAL TECH
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, pathological studies have shown that the tissue structure of the rotator cuff insertion cannot return to its normal shape after surgical reconstruction, and the main problem is that the fibrocartilage layer in the healed tendon-bone interface cannot be regenerated and is only replaced by scar tissue, resulting in the formation of an indirect insertion. The mechanical properties of the point are far lower than the normal direct stop, and it is easy to re-tear

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A composite tendon repair material and its preparation method
  • A composite tendon repair material and its preparation method
  • A composite tendon repair material and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0038] After completing the above-mentioned five steps, obtain a sheet-like extracellular matrix material.

[0039] Get the extracellular matrix material obtained in part, and further complete the following steps to obtain the base layer 11. Includes: (6) Fixed

[0042] Each active unit has the same structure, and is described below by taking the first unit 12 as an example. As shown in Figure 2 and Figure 3,

[0045] The above-mentioned slurry is then put into a plastic freeze-drying mold for freeze-drying. Pre-freeze the paste to ‑45°C,

[0046] The freeze-drying mold may have a sloped bottom. Shape the freeze-drying mold so that the first active layer 121 and the second active layer

[0047] After obtaining the cover layer 123 of the active unit, the first active layer 121 and the second active layer 122, the three are overlapped.

[0048] As shown in FIG. 4, the active units 12, 13 and 14 are obtained by extruding the laminated structure. live after extrusion

[0049] In a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention relates to a composite tendon repair material, characterized in that the composite tendon repair material includes a base layer and at least one active unit; the base layer and the at least one active unit are fixed to each other; the base layer includes an extracellular matrix material ; Each active unit in the at least one active unit comprises a first active layer, a second active layer and a cover layer respectively; the first active layer comprises an extracellular matrix material and a first active component; the second active The layer comprises an extracellular matrix material and a second active ingredient; each active unit is prepared by mechanical compression. The repair material promotes the growth and repair of bone tissue wound and the growth and repair of tendon tissue wound at the tear of tendon and bone respectively, and finally promotes the healing of the junction of tendon and bone, effectively forming a transition from bone, calcified cartilage, fibrocartilage to Insertion-like structure of the tendon. This construct will enable the repair of giant rotator cuff tendon tears.

Description

A kind of composite tendon repair material and preparation method thereof technical field The present invention relates to medical implant medical device, be specifically related to a kind of tendon repair material with composite structure, the The material has a growth factor with a quantitative gradient change per unit length, which effectively realizes the establishment of tendon-bone insertion points, and the preservation of tendons. Effective repair. The present invention further includes a preparation method of the composite tendon repair sheet material. Background technique Rotator cuff is the sleeve formed by the tendon of supraspinatus, infraspinatus, subscapularis, teres minor in front of humeral head, on top, behind The sleeve-like muscle-like structure realizes the functions of controlling and rotating the arm. The rotator cuff tendon becomes inflamed and degraded when overloaded It causes pain, lipidation, and calcification, which reduces the mechanica...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/36A61L27/20A61L27/22A61L27/24A61L27/54A61F2/08
CPCA61L27/3633A61L27/3662A61L27/3687A61L27/3691A61L27/222A61L27/24A61L27/20A61L27/227A61L27/54A61F2/0811A61L2300/252A61L2300/414A61L2430/10A61F2002/0847
Inventor 赵威张晋辉赵博李学军夏磊磊王洪权门福民
Owner BEIJING BIOSIS HEALING BIOLOGICAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com