The invention relates to a liquid die forging and rolling compound formation method for a GH4033 high-temperature alloy irregular-section large ring piece. The method comprises the following steps of: 1) smelting; 2) performing liquid die forging, namely fixing a liquid die forging mold on an indirect extrusion casting machine, pouring a quantitative amount of alloy solution into the liquid die forging mold at the pouring temperature of between 1350 and 1450 DEG C, pressurizing at the speed of 40 to 50 mm/s, filling for 1 to 6 seconds at the specific pressure of 300 to 400 MPa, keeping the pressure for 50 to 90 seconds, and thus obtaining a similarly final section ring blank; 3) homogenizing; 4) performing afterheat isothermal rolling, namely cooling the homogenized similarly final section ring blank to the temperature of between 1100 and 1140 DEG C, and performing afterheat isothermal rolling on a radial shaft compound ring rolling machine; 5) performing thermal treatment, namely performing solid solution instant thermal treatment, keeping the ring blank at the temperature of between 900 and 1000 DEG C for 1 to 2 hours, performing air cooling, then heating to the temperature of 1080 DEG C, keeping the temperature for 8 hours, performing air cooling to the temperature of 750 DEG C, keeping the temperature for 16 hours, and performing air cooling; and 6) finishing.