Active oligopeptide GRGDS and application thereof in preparation of drug for preventing and treating ischemic cerebrovascular diseases

A cerebrovascular disease and ischemic technology, which is applied in the field of active short peptides, namely GRGDS, for the preparation of anti-ischemic cerebrovascular disease products, and achieves the effect of good application prospects.
CN112138140AInactive Publication Date: 2020-12-29上海萃微生物医药科技有限公司
0 Cites 1 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
上海萃微生物医药科技有限公司
Publication Date
2020-12-29
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to the technical field of medicine, food, reagents and the like, in particular to application of oligopeptide GRGDS in preparation of a drug for preventing and treating ischemiccerebrovascular diseases. Pharmacological tests of a rat local cerebral ischemia model show that the oligopeptide can significantly reduce the cerebral infarction volume of a cerebral ischemia rat, significantly improve the nerve injury of the rat after ischemia and reduce the apoptosis of nerve cells. The oligopeptide has a strong brain protection effect, is easy to penetrate through a blood brain barrier due to small molecular weight, and has remarkable advantages. Therefore, the oligopeptide GRGDS has good application prospects in preparation of the drug for preventing and treating ischemiccerebrovascular diseases.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to the technical fields of medicine, food, reagents, etc., in particular to the new use of an active short peptide, and more specifically to the use of an active short peptide, namely GRGDS, for the preparation of anti-ischemic cerebrovascular disease products new uses. Background technique

[0002] Ischemic cerebrovascular disease (ischemic stroke) is one of the diseases with the highest morbidity, mortality and disability rate in the world, which greatly threatens the health and quality of life of human beings, especially the elderly, and has become a global Huge burden on society's health resources. Clinically, the mortality and disability rate of ischemic stroke has taken the first place among neurological diseases. At present, there are few effective drugs used in the treatment of ischemic cerebrovascular disease at home and abroad. Therefore, it is of great significance to carry out in-depth research on drug preve...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More