Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Purpose of L-arabinose on aspect of inhibiting gas generation of sorbitol in intestinal tracts

A technology of arabinose and its application, applied in the field of L-arabinose inhibiting sorbitol intestinal gas production, which can solve problems such as application limitation and intestinal explosion

Inactive Publication Date: 2021-01-12
唐传生物科技(厦门)有限公司
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, sorbitol and mannitol are fermented and decomposed by microorganisms in the intestinal tract, which will produce flammable and explosive gases, mainly including hydrogen. The use of the sugar alcohols sorbitol and mannitol in bowel preparation is limited due to the very high risk of electrical sparks during resection of bowel polyps or resection of tumors leading to bowel explosions

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] In this example, the effect of L-arabinose on inhibiting the hydrogen production of sorbitol in the intestinal tract was investigated by hydrogen breath test.

[0102] The principle of the hydrogen breath test (HBT):

[0103] After sorbitol passes through the intestine, it is fermented by the microorganisms in the intestine to produce H 2 , H 2 It can diffuse into the blood through the intestinal mucosa, reach the alveoli through blood circulation, and be exhaled out of the body through gas exchange. Therefore, L-arabinose can inhibit the fermentation of sorbitol in the intestinal tract to produce H by measuring the hydrogen gas exhaled. 2 role.

[0104] 1. Experimental method

[0105] Six healthy beagle dogs, half male and half male, weighing 20-21kg, were fasted for 12 hours before the experiment, and were forbidden to drink water for 2 hours before the experiment.

[0106] Two-period self-controlled experimental design was used for the experiment, and healthy bea...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a purpose of L-arabinose on an aspect of inhibiting gas generation of sorbitol in intestinal tracts. Particularly, the invention relates to a purpose of arabinose. The arabinose is used for preparing a composition, and the composition is used for purposes selected from following one or multiple groups: (a) degradation of sugar alcohol is inhibited; (b) the composition is used for an intestinal tract preparation of the sugar alcohol; and (c) the composition is used for electrocoagulation and / or electrocision treatment of intestinal tract diseases.

Description

technical field [0001] The invention relates to the field of medicines, in particular to the use of L-arabinose in inhibiting intestinal gas production of sorbitol. Background technique [0002] Bowel preparation methods are different, and the effects are also different. It is very important to choose a bowel preparation method that has good bowel cleansing effect, less side effects, and a wide range of applications. [0003] Sorbitol and mannitol are used as intestinal preparation drugs. Oral sorbitol and mannitol can be used for colonoscopy and treatment under colonoscopy. Sorbitol and mannitol mainly form a hypertonic environment in the intestinal tract, increase the water in the intestinal tract, soften the stool, promote intestinal peristalsis, and achieve the purpose of cleaning the intestinal tract. [0004] Although there are other medicines for intestinal preparation in the prior art, such as compound polyethylene glycol electrolyte powder, magnesium sulfate, sodiu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/7004A61P1/00A61P41/00
CPCA61K31/7004A61P1/00A61P41/00
Inventor 陈旭王羽娟林卫军石国良洪诗群萧舜之郭志坚
Owner 唐传生物科技(厦门)有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com