Synthesis method of active bromine-containing bagasse xylan ester-g-AM

Abstract

The invention discloses a synthesis method of active bromine-containing bagasse xylan ester-g-AM. The method comprises the following steps: taking bagasse xylan as a main raw material, taking ammoniumpersulfate / sodium hydrogen sulfite as a redox system initiator and taking acrylamide as a grafting monomer; synthesizing a bagasse xylan grafted acrylamide copolymer, namely bagasse xylan-g-AM, in awater solvent through a free radical reaction; furthermore, taking 3-bromopyruvic acid as an esterifying agent, taking 4-dimethylaminopyridine and tetrabutyl titanate as a composite catalyst, and synthesizing a final product active bromine-containing derivative bagasse xylan bromopyruvate-g-AM through catalytic esterification. The solubility of the obtained product in water is improved by 10%, thethermal stability is improved, the biological activity is also improved, and the application of bagasse xylan in the fields of medicines, polymer functional materials and the like is broadened.

Description

technical field [0001] The invention relates to the field of biomass functional materials, in particular to a synthesis method of active bromine-containing bagasse xylan ester-g-AM. Background technique [0002] The strong drug resistance of tumor cells has always been a difficult problem in the field of clinical medicine, so finding anticancer drugs with high efficiency and low toxicity is an important direction of current cancer research. Due to its unique structure, xylan has a variety of biological functions, such as basic non-toxicity, good biodegradability, good biocompatibility, regeneration, low oxygen osmotic pressure and other functions, especially its certain Inhibit the proliferation ability of cancer cells. However, the hydroxyl groups on the C2 and C3 positions of bagasse xylan are easy to form a strong hydrogen bond network, which makes it less active and limits its functional application. Therefore, it is important to enhance the activity of bagasse xylan by...

AI Technical Summary

Problems solved by technology

However, the hydroxyl groups on the C2 and C3 positions of bagasse xylan are easy to form a strong hydrogen bond network, which makes it less active and limits its functional application. Therefore, it is important to enhance the activity of bagasse xylan by chemical modification. value

In addition, the water solubility of bagasse xylan derivatives modified by esterification and grafting still needs to be improved.

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