Establishment of a highly sensitive detection method for dengue virus based on nano-magnetic beads immunochromatography

A technology of nano-magnetic beads and dengue virus, which is applied in measurement devices, analytical materials, biological material analysis, etc., can solve the problems of cumbersome virus separation operation, unfavorable large-scale detection, unsuitable early diagnosis, etc. The effect of simplicity and improved sensitivity
CN112444628BActive Publication Date: 2022-08-02CHINESE ACAD OF INSPECTION & QUARANTINE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHINESE ACAD OF INSPECTION & QUARANTINE
Publication Date
2022-08-02

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Abstract

The invention discloses the establishment of a high-sensitivity detection method for dengue virus based on nano-magnetic bead immunochromatography technology, the preparation of dengue virus nano-magnetic bead-antibody probes; the assembly of nano-magnetic bead test strips; the use of nano-magnetic bead test strips to detect For the detection of dengue virus, a new method for the detection of dengue virus based on the immunochromatographic technology of nano-magnetic beads is established by using the magnetic enrichment and separation function of nano-magnetic beads and the characteristic that the color signal can be observed by the naked eye, which can effectively improve the detection sensitivity. The method is simple and easy to operate, and can be used for large-scale rapid diagnosis.
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Description

technical field

[0001] The invention relates to the technical field of nano-magnetic beads immunochromatography. Specifically, a highly sensitive detection method for dengue virus was established based on nano-magnetic beads immunochromatography technology. Background technique

[0002] Dengue fever (Dengue Fever) is an acute infectious disease caused by Dengue Virus (DENV) of the genus Flavivirus. Dengue virus is transmitted by vector insects such as Aedes aegypti and Aedes albopictus and causes dengue fever. It is prevalent in tropical and subtropical regions of the world. Mild symptoms include persistent fever, headache, joint pain, muscle pain, etc., and severe disease has a high mortality rate. High dengue hemorrhagic fever and dengue shock syndrome. The rather fast-spreading viral disease has seen a 30-fold increase in global incidence over the past 50 years due to factors such as global warming and blind urban sprawl. According to statistics, 390 million people wor...

Claims

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