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Preparation process of hypoglycemic pharmaceutical composition

A preparation process and composition technology are applied in the field of preparation technology of hypoglycemic pharmaceutical compositions, which can solve the problems of hypoglycemia symptoms, affect the health of patients, expensive raw materials, etc. Effect, effect of improving hypoglycemic effect

Inactive Publication Date: 2021-03-23
王雪克
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At the same time, the existing hypoglycemic drugs are quickly released after the patient takes them, lowering the blood sugar level in the patient's body or slowly released, and can control blood sugar fluctuations for a long time. The symptoms of hypoglycemia caused by the drugs taken affect the patient's health. At the same time, the existing hypoglycemic drugs have problems such as complicated preparation process, expensive raw materials, and poor pathological and toxicological test results, which are not suitable for most people.

Method used

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  • Preparation process of hypoglycemic pharmaceutical composition
  • Preparation process of hypoglycemic pharmaceutical composition
  • Preparation process of hypoglycemic pharmaceutical composition

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Experimental program
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Effect test

Embodiment approach

[0048] As an embodiment of the present invention, after the granulation of the slow-release particles 3 is completed, the surface is sprayed with an appropriate amount of shellac and propolis mixed in equal proportions, that is, the promoting solution; The number of times is two or more; the number of structural layers in the finished soft capsule is three or more, and the number of suspensions 2 filled in the gaps between adjacent structures in each structural layer is different; The amount of suspension 2 filled in the gap between adjacent structural layers in the center is less than the amount of suspension 2 filled in the gap between adjacent structural layers of the soft capsule shell 1;

[0049] During work, by spraying the accelerating solution on the surface of the sustained-release granule 3, the surface of the sustained-release granule 3 is relatively closed, so as to avoid the dissolution of the sustained-release granule 3 in the soft capsule into the suspension 2 du...

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Abstract

The invention belongs to the technical field of pharmaceutical compositions, and particularly relates to a preparation process of a hypoglycemic pharmaceutical composition. The process comprises the following raw materials of 20 to 23 parts of cordyceps sinensis, 22 to 24 parts of cortex cinnamomi, 18 to 20 parts of folium cortex eucommiae, 15 to 19 parts of fructus corni, 13 to 17 parts of radixastragali, 16 to 18 parts of rhizoma coptidis, 15 to 20 parts of rhizoma dioscoreae, 14 to 16 parts of rhizoma anemarrhenae, 14 to 16 parts of folium mori, 13 to 15 parts of coprinus comatus, 10 to 13parts of momordica charantia and 5-8 parts of fructus crataegi. The pharmaceutical composition disclosed by the invention has a remarkable effect of controlling the blood glucose level in a patient,is simple in preparation process and low in production cost, and does not easily cause hypoglycemia symptoms after being taken.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical compositions, in particular to a preparation process of a hypoglycemic pharmaceutical composition. Background technique [0002] Diabetes is a common disease caused by the interaction of genetic and environmental factors. Clinically, hyperglycemia is the main sign, and common symptoms include polydipsia, polyuria, polyphagia, and weight loss. Diabetes can cause damage to multiple systems in the body. It causes absolute or relative insufficient secretion of insulin and decreased sensitivity of target tissue cells to insulin, causing a series of metabolic disorder syndromes such as protein, fat, water and electrolyte, among which hyperglycemia is the main symbol. Type I diabetes mostly occurs in adolescents, who rely on exogenous insulin supplementation to maintain life; type II diabetes is more common in middle-aged and elderly people, and the body is not sensitive enough to insulin, that i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K9/52A61K47/36A61K47/38A61P3/10
CPCA61K9/4808A61K9/4891A61K36/068A61K36/07A61K36/40A61K36/42A61K36/46A61K36/481A61K36/54A61K36/605A61K36/718A61K36/734A61K36/8945A61K36/8964A61K47/36A61K47/38A61K2236/19A61P3/10A61K2300/00
Inventor 王雪克王安
Owner 王雪克
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