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Single-light-source multi-sample fluorescence detection optical system and working method thereof

A fluorescence detection and optical system technology, applied in the field of fluorescence detection optical system, to achieve the effect of stable detection signal

Active Publication Date: 2021-03-30
SUZHOU MOLARRAY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the difficulty lies in: the design of the plastic light guide rod, that is, the size of the plastic light guide rod needs to meet certain conditions in order to have a better working state

Method used

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  • Single-light-source multi-sample fluorescence detection optical system and working method thereof
  • Single-light-source multi-sample fluorescence detection optical system and working method thereof
  • Single-light-source multi-sample fluorescence detection optical system and working method thereof

Examples

Experimental program
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Embodiment 1

[0072] Embodiment one, such as figure 1 As shown, a fluorescence detection optical system with a single light source and multiple samples includes: a light source emitting component 100, a light source receiving component 200, and a light guide-reaction component 300;

[0073] Wherein, the light source emitting assembly 100 includes: LED lamp 101 (using LED as the light source, the service life can reach 20,000 hours, of course, it is also feasible to use other monochromatic light sources, such as: halogen tungsten lamp), the first convex lens 102 (spherical mirror), the second Two convex lenses 103 (spherical mirror), excitation filter 104, light guide strip assembly 105; the LED lamp faces downward, the convex surface of the first convex lens 102 faces downward, and the second convex lens 103 is arranged on the first Below the convex lens 102 and the convex surface of the second convex lens 103 faces downward;

[0074] The upper surface of the second convex lens is circular...

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Abstract

The invention discloses a single-light-source multi-sample fluorescence detection optical system and a working method thereof, and belongs to the field of molecular diagnosis detection instruments. The design key points of the system are that system comprises a light source emitting assembly, a light source receiving assembly and a light guide reaction assembly. The light source emitting assemblycomprises a light source, a lens assembly, an excitation light filter and a light guide strip assembly. The light guide strip assembly comprises N light guide strips which are vertically arranged; thelight guide reaction assembly comprises a light guide plate and a reaction tank assembly, the light source receiving assembly comprises a CCD camera, a camera lens and a receiving optical filter. A camera lens is arranged at the lower end part of the CCD camera, and a receiving optical filter is arranged at the lower end part of the camera lens; the CCD camera is arranged above the light guide plate, and a lens of the CCD camera faces the light guide plate. The invention aims to provide the single-light-source multi-sample fluorescence detection optical system and the working method thereof,and 128 samples can be detected at one time.

Description

technical field [0001] The present invention relates to the fields of a medical inspection instrument and a molecular diagnosis instrument, and more specifically relates to a fluorescence detection optical system with a single light source and multiple samples and a working method thereof. Background technique [0002] Multi-sample fluorescence detection optical system is a development direction of molecular diagnostic detection equipment. [0003] Regarding the multi-sample fluorescence detection optical system, the existing technologies are as follows: [0004] Shanghai Lanyi Technology Co., Ltd. discloses a multi-sample microbial detection device in CN104964927A, which simultaneously completes the multi-parameter detection of colorimetry, turbidimetry and fluorescence of a matrix sample hole by scanning, and can simultaneously detect 16 samples to be tested . The detection method of the detection device of the invention is simple and efficient, and has good application ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64G01J3/44G01J3/28G01J3/10
CPCG01N21/645G01N21/64G01J3/10G01J3/4406G01J3/2823G01N2021/6482G01N2021/6463G01N2021/6417
Inventor 李晓刚王威梅宗羲李慧王野聂晶
Owner SUZHOU MOLARRAY CO LTD